Patents by Inventor Aurelien DAYNES

Aurelien DAYNES has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250076290
    Abstract: Method for assaying a target analyte in a biological sample in liquid medium, comprising: contacting the sample with first magnetic particles bearing a first receptor specific to a first analyte site of attachment to form first complexes; applying a first magnetic field to locally combine the formed complexes formed and optionally to agglomerate interfering complexes to form interfering aggregates; negating the applied magnetic field; adding second magnetic particles to a liquid medium that bear a second receptor specific to a second analyte site of attachment; measuring a first quantity of interfering aggregates; applying a second magnetic field to form second complexes; measuring a second quantity of the collective amount of interfering aggregates and second complexes to determine an amount of formed second complexes as a function of the first quantity, and deducing the amount of analyte present in the sample and, optionally, the amount of interfering analyte.
    Type: Application
    Filed: December 13, 2022
    Publication date: March 6, 2025
    Applicant: HORIBA ABX SAS
    Inventors: Aurélien DAYNES, Nevzat TEMUROK
  • Publication number: 20240182990
    Abstract: The present invention concerns a method for the molecular detection of an infectious agent based on isothermal amplification by recombinase polymerase amplification (RPA) combined with a Magnetic Field-Enhanced Agglutination (MFEA) readout.
    Type: Application
    Filed: March 9, 2021
    Publication date: June 6, 2024
    Inventors: Chantal FOURNIER-WIRTH, Fanny LEON, Jean-François CANTALOUBE, Jean-Pierre MOLÈS, Elena PINCHON, Aurélien DAYNÈS, Charly MAYRAN
  • Publication number: 20210131944
    Abstract: The invention relates to a method for counting particles, particularly blood cells, in a sample, using a lensless optical imaging device. The sample is arranged between a light source and an image sensor. The sample is illuminated by a light source and an image is acquired by the image sensor, said image sensor being exposed to a light wave called an exposition wave. A digital propagation operator is applied to the acquired image so as to obtain a complex amplitude of the exposition wave according to a surface facing the image sensor. An image, called a reconstructed image, is formed from the modulus and/or the phase of said complex amplitude, on which image the particles to be counted appear in the form of regions of interest. The method then comprises a step of selecting the regions of interest corresponding to the particles to be counted.
    Type: Application
    Filed: December 20, 2017
    Publication date: May 6, 2021
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES AlTERNATIVES, HORIBA ABX SAS
    Inventors: Pierre BLANDIN, Anais ALI-CHERIF, Estelle GREMION, Sebastien RAIMBAULT, Oliver CIONI, Aurelien DAYNES
  • Publication number: 20200326269
    Abstract: The invention is a method for estimating a representative volume of particles of interest (10 i) immersed in a sample, the sample extending in at least one plane, referred to as the sample plane (P 10), the sample comprising a sphering agent, capable of modifying the shape of the particles, the method comprising the following steps: a) illuminating the sample by means of a light source (11), the light source emitting an incident light wave (12) propagating towards the sample (10) along a propagation axis (Z); b) acquiring, by means of an image sensor (16), an image (I 0) of the sample (10), formed in a detection plane (P 0), the sample being arranged between the light source (11) and the image sensor (16), each image being representative of a light wave (14) referred to as an exposure light wave, to which the image sensor (16) is exposed under the effect of illumination; c) using the image of the sample (I 0), acquired during step b), and a holographic propagation operator, to calculate a complex expression (
    Type: Application
    Filed: October 30, 2018
    Publication date: October 15, 2020
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, HORIBA ABX SAS
    Inventors: Pierre BLANDIN, Anais ALI-CHERIF, Aurelien DAYNES, Estelle GREMION, Damien ISEBE
  • Publication number: 20160153972
    Abstract: The present invention relates to a flow assay method in a liquid medium for an object (or element) of interest via the formation of aggregates of particles that are surface-functionalized by at least one functionalizing molecule, or receptor, specific for said object of interest.
    Type: Application
    Filed: March 11, 2014
    Publication date: June 2, 2016
    Inventors: Aurelien DAYNES, Gilles CAUET, Jean-Philippe GINEYS, Philippe NERIN, Jerome BIBETTE