Patents by Inventor Aurelien Lathuiliere

Aurelien Lathuiliere has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TREATMENT AND PREVENTION OF ALZHEIMER'S DISEASE
    Publication number: 20220332813
    Abstract: The present invention provides methods and compositions for reducing internalization and/or trafficking of tau in neuronal cells comprising contacting the cells with an effective amount of an LRP1 and/or SorLA antagonist. The invention further provides a method of treating or preventing Alzheimer's disease in a subject in need thereof, comprising administering to the subject an effective amount of an LRP1 and/or SorLA antagonist.
    Type: Application
    Filed: April 3, 2022
    Publication date: October 20, 2022
    Inventors: Dudley K. Strickland, Joanna Cooper, Selen M. Catania, Mary M. Migliorini, Brian Hampton, Bradley T. Hyman, Aurelien Lathuiliere
  • IMPLANTABLE CAPSULE
    Publication number: 20220287959
    Abstract: Implantable capsule comprising a cell receiving portion (2) comprising a porous membrane (5) surrounding a cell receiving chamber (13) for receiving immortalized cells in a liquid media therein for the secretion of therapeutic agents. The capsule further comprises a cell support matrix (7) inserted within the cell receiving chamber (13) configured for the arrangement of the immortalized cells within the cell receiving chamber.
    Type: Application
    Filed: August 12, 2020
    Publication date: September 15, 2022
    Inventors: AURÉLIEN LATHUILIÈRE, JULIEN GROGG, NICOLAS MACH
  • IMMORTALIZED MYOBLAST CELL LINES AND USES THEREOF
    Publication number: 20220265727
    Abstract: The present invention relates to immortalized human cells particularly useful for cell encapsulation therapy and methods of preparation and use thereof.
    Type: Application
    Filed: August 12, 2020
    Publication date: August 25, 2022
    Inventors: AURÉLIEN LATHUILIÈRE, NICOLAS MACH, PATRICK SALMON
  • Biomolecular cell encapsulation device and methods of implantation
    Patent number: 9950149
    Abstract: Provided herein is a cell encapsulation device comprising an internal chamber suitable for holding biological agents, wherein the internal chamber is disposed between a first semipermeable layer and a second semi-permeable layer, and the first and second semi-permeable layers are mounted on a supporting frame surrounding a perimeter of the internal chamber; wherein the supporting frame comprises a first frame element and a second frame element, and the first and second frame elements co-operate to position the first and second semipermeable layers at a predetermined separation distance between the layers.
    Type: Grant
    Filed: April 24, 2013
    Date of Patent: April 24, 2018
    Assignees: NESTEC S.A., ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
    Inventors: Aurelien Lathuiliere, Nicolas Bouche, Bernard Schneider
  • ENCAPSULATION DEVICE
    Publication number: 20160184569
    Abstract: Provided herein is a cell encapsulation device comprising an internal chamber suitable for holding biological agents, wherein the internal chamber is disposed between a first semipermeable layer and a second semi-permeable layer, and the first and second semi-permeable layers are mounted on a supporting frame surrounding a perimeter of the internal chamber; wherein the supporting frame comprises a first frame element and a second frame element, and the first and second frame elements co-operate to position the first and second semipermeable layers at a predetermined separation distance between the layers.
    Type: Application
    Filed: April 24, 2013
    Publication date: June 30, 2016
    Inventors: Aurelien Lathuiliere, Nicolas Bouche, Bernard Schneider