Patents by Inventor Aurelio Balsalobre

Aurelio Balsalobre has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • dft-A gene, diagnostic and therapeutic uses thereof
    Patent number: 6054571
    Abstract: The present invention relates to a novel gene regulated by FOS and RAS transforming pathways, which is identified as dft-A, and which comprises the sequence set forth in FIG. 3. There is also disclosed the novel dft-A protein and an antibody recognizing same. The present invention also relates to a diagnostic method of identifying dft-A mutations in cancer or other diseases in a biological sample of a patient, which comprises: a) subjecting DNA present in the patient's sample to gene sequencing; and b) comparing the sequenced DNA with the sequence of dft-A gene to identify dft-A mutations. The present invention also relates to a diagnostic method of identifying change in dft-A protein level in cancer or other diseases in a biological sample of a patient, which comprises: a)subjecting the patient's sample to the anti-dft-A antibody to form an antibody-dft-A protein complex; and b) detecting the antibody-dft-A protein complex to determine the dft-A protein level in the biological sample.
    Type: Grant
    Filed: May 11, 1998
    Date of Patent: April 25, 2000
    Assignee: Institut de Recherches Cliniques de Montreal
    Inventors: Paul Jolicoeur, Aurelio Balsalobre