Patents by Inventor Austen Pimm

Austen Pimm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Imidazoquinoline compounds
    Patent number: 9045472
    Abstract: Disclosed herein are a compound of formula (I) and pharmaceutically acceptable salts thereof, processes for preparing the same, pharmaceutical compositions containing the same, and methods of using the same.
    Type: Grant
    Filed: December 16, 2011
    Date of Patent: June 2, 2015
    Assignees: ASTRAZENECA AB, SUMITOMO DAINIPPON PHARMA CO., LTD.
    Inventors: Thomas McInally, Austen Pimm
  • Salts 756
    Patent number: 8476288
    Abstract: The invention provides salts of 4-(dimethylamino)butyl 2-(4-((2-amino-4-methyl-6-(pentylamino)pyrimidin-5-yl)methyl)phenyl)acetate, pharmaceutical compositions containing them and their use in therapy.
    Type: Grant
    Filed: May 20, 2010
    Date of Patent: July 2, 2013
    Assignees: AstraZeneca AB, Dainippon Sumitomo Pharma Co., Ltd.
    Inventors: Nicholas James Bennett, Thomas McInally, Austen Pimm, Yoshiaki Isobe
  • NOVEL COMPOUNDS
    Publication number: 20120189646
    Abstract: Disclosed herein are a compound of formula (I) and pharmaceutically acceptable salts thereof, processes for preparing the same, pharmaceutical compositions containing the same, and methods of using the same.
    Type: Application
    Filed: December 16, 2011
    Publication date: July 26, 2012
    Inventors: Thomas MCINALLY, Austen PIMM
  • Chemical Compounds 637
    Publication number: 20120077801
    Abstract: The present invention provides a compound of a formula (I): wherein the variables are defined herein; to a process for preparing such a compound; and to the use of such a compound in the treatment of a PDE4 mediated disease state.
    Type: Application
    Filed: August 3, 2011
    Publication date: March 29, 2012
    Inventors: Roger Victor Bonnert, Rhona Jane Cox, Simon De Sousa, Mark Dickinson, Simon Fraser Hunt, Austen Pimm, Hitesh Jayantilal Sanganee, Frank Burkamp, Premji Meghani
  • SALTS 756
    Publication number: 20100298364
    Abstract: The invention provides salts of 4-(dimethylamino)butyl 2-(4-((2-amino-4-methyl-6-(pentylamino)pyrimidin-5-yl)methyl)phenyl)acetate, pharmaceutical compositions containing them and their use in therapy.
    Type: Application
    Filed: May 20, 2010
    Publication date: November 25, 2010
    Applicants: AstraZeneca AB, Dainippon Sumitomo Pharma Co., Ltd.
    Inventors: Nicholas James BENNETT, Thomas McInally, Austen Pimm, Stephen Thom, Yoshiaki Isobe
  • Chemical Compounds 637: Pyridopyrimidinediones as PDE4 Inhibitors
    Publication number: 20100204203
    Abstract: The present invention provides a compound of a formula (I), wherein the variables are defined herein; to a process for preparing such a compound; and to the use of such a compound in the treatment of a PDE4 mediated disease state.
    Type: Application
    Filed: January 10, 2008
    Publication date: August 12, 2010
    Inventors: Roger Victor Bonnert, Frank Burkamp, Rhona Jane Cox, Simon de Sousa, Mark Dickinson, Simon Fraser Hunt, Premji Meghani, Austen Pimm, Hitesh Jayantilal Sanganee
  • Adamantane derivatives
    Publication number: 20090176853
    Abstract: The invention provides adamantane derivatives of formula (I), a process for their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions, and their use in therapy. In formula (I) D represents CH2 or CH2CH2, E represents C(O)NH or NHC(O) and R3 represents a group of formula (I).
    Type: Application
    Filed: December 4, 2008
    Publication date: July 9, 2009
    Inventors: Lilian Alcaraz, Moya Caffrey, Mark Furber, Timothy Luker, Michael Mortimore, Austen Pimm, Philip Thorne, Paul Willis
  • Novel Tricyclic Spiropiperidine Compounds, Their Synthesis and Their Uses as Modulators of Chemokine Receptor Activity
    Publication number: 20090176815
    Abstract: Compounds of formula (I) wherein R1, R3, R4, R5, R6, R7, and R10 are as defined in the specification, are described. The present invention also relates to pharmaceutical composition comprising said compounds and to the use of said compounds in therapy. The present invention further relates to processes for the preparation of said compounds and to new intermediates useful in the preparation thereof. Beside, the invention relates to salts and polymorphic forms of the new compounds as well as the preparation thereof.
    Type: Application
    Filed: January 16, 2009
    Publication date: July 9, 2009
    Inventors: Tomas Eriksson, Martin Hemmerling, Bo-Goran Josefsson, Svetlana Ivanova, Marguerite Mensonides-Harsema, John Mo, John Pavey, Austen Pimm, James Reuberson, Hakan Schulz, Per Strandberg
  • Chemical Compounds 637
    Publication number: 20090124596
    Abstract: The present invention provides a compound of a formula (I): wherein the variables are defined herein; to a process for preparing such a compound; and to the use of such a compound in the treatment of a PDE4 mediated disease state.
    Type: Application
    Filed: January 10, 2008
    Publication date: May 14, 2009
    Inventors: Roger Victor Bonnert, Frank Burkamp, Rhona Jane Cox, Simon De Sousa, Mark Dickinson, Simon Fraser Hunt, Premji Meghani, Austen Pimm, Hitesh Jayantilal Sanganee
  • Compounds
    Patent number: 7498338
    Abstract: The invention provides compounds of formula (I) wherein m, R1, n, R2, q, X, Y, Z, t, R3, R4, R5, R6, R7 and R8 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
    Type: Grant
    Filed: November 15, 2004
    Date of Patent: March 3, 2009
    Assignee: AstraZeneca AB
    Inventors: Andrew Baxter, Nafizal Hossain, Svetlana Ivanova, Marguerite Mensonides-Harsema, Austen Pimm, James Reuberson
  • Novel Compounds 243
    Publication number: 20080167332
    Abstract: Compounds of formula (I) wherein R1, R3, R4, R5, R6, R7, and R10 are as defined in the specification, are described. The present invention also relates to pharmaceutical composition comprising said compounds and to the use of said compounds in therapy. The present invention further relates to processes for the preparation of said compounds and to new intermediates useful in the preparation thereof. Beside, the invention relates to salts and polymorphic forms of the new compounds as well as the preparation thereof.
    Type: Application
    Filed: July 18, 2007
    Publication date: July 10, 2008
    Inventors: Scott Gibson, Barry Elkins, Mike Rogers, Ian Hassall, Hong Gu, Zhenyu Wang, Vinod Kumar, Synthana Suresh Kumar, Santosh Kavitake, Sidda Lingesha, Eric Merifield, David Ennis, John Pavey, Austen Pimm, James Reuberson, Bo-Goran Josefsson, Martin Hemmerling, Svetlana Ivanova, Marguerite Mensonides-Harsema, Hakan Schulz, John Mo, Tomas Eriksson, Per Strandberg
  • Adamantane derivatives
    Publication number: 20080139636
    Abstract: The invention provides adamantane derivatives of formula (I), a process for their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions, and their use in therapy. In formula (I) D represents CH2 or CH2CH2, E represents C(O)NH or NHC(O) and R3 represents a group of formula (I).
    Type: Application
    Filed: June 20, 2007
    Publication date: June 12, 2008
    Inventors: Lilian Alcaraz, Moya Caffrey, Mark Furber, Timothy Luker, Michael Mortimore, Austen Pimm, Philip Thorne, Paul Willis
  • Novel compounds
    Publication number: 20070129393
    Abstract: The invention provides compounds of formula (I) wherein m, R1, n, R2, q, X, Y, Z, t, R3, R4, R5, R6, R7 and R8 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
    Type: Application
    Filed: November 15, 2004
    Publication date: June 7, 2007
    Inventors: Andrew Baxter, Nafizal Hossain, Svetlana Ivanova, Marguerite Mensonides-Harsema, Austen Pimm, James Reuberson
  • Adamantane derivatives, processes for their preparation and pharmaceutical composition containing them
    Patent number: 7227038
    Abstract: The invention provides compounds of formula in which m, n, R1, R2, R3, R4, and R5, have the meanings defined in the specification; processes for their preparation; pharmaceutical compositions containing them; a process for preparing the pharmaceutical compositions; and their use in therapy.
    Type: Grant
    Filed: February 19, 2004
    Date of Patent: June 5, 2007
    Assignee: AstraZeneca AB
    Inventors: Moya Caffrey, Rhonan Ford, Austen Pimm
  • Adamantane derivatives
    Publication number: 20070082957
    Abstract: The invention provides adamantane derivatives of formula (I), a process for the their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions, and their use in therapy. In formula (I) D represents CH2 or CH2CH2, E represents C(O)NH or NHC(O) and R3 represents a group of formula (I).
    Type: Application
    Filed: September 29, 2006
    Publication date: April 12, 2007
    Inventors: Lilian Alcaraz, Moya Caffrey, Mark Furber, Timothy Luker, Michael Mortimore, Austen Pimm, Philip Thorne, Paul Willis
  • Adamantane derivatives
    Patent number: 7132457
    Abstract: The invention provides adamantane derivatives of formula (I), a process for their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions, and their use in therapy. In formula (I) D represents CH2 or CH2CH2, E represents C(O)NH or NHC(O) and R3 represents a group of formula (I).
    Type: Grant
    Filed: March 31, 2004
    Date of Patent: November 7, 2006
    Assignee: AstraZeneca AB
    Inventors: Lilian Alcaraz, Mark Furber, Michael Mortimore, Austen Pimm, Philip Thorne, Paul Willis
  • Adamantane derivatives, processes for their preparation and pharmaceutical composition containing them
    Publication number: 20060160904
    Abstract: The invention provides compounds of formula (I) in which m, n, R?1, R?2, R?3, R?4 and R?5 have the meanings defined in the specification; processes for their preparation; pharmaceutical compositions containing them; a process for preparing the pharmaceutical compositions; and their use in therapy.
    Type: Application
    Filed: February 19, 2004
    Publication date: July 20, 2006
    Inventors: Moya Caffrey, Rhonan Ford, Austen Pimm
  • Use of phenylheteroakylamine derivatives
    Patent number: 6887871
    Abstract: There is disclosed the use of a compound of formula (I) wherein R1, R2, X, Y, V, W and Z are as defined in the specification, and pharmaceutically acceptable salts, enantiomers or racemates thereof, in the manufacture of a medicament, for the treatment or prophylaxis of diseases or conditions in which inhibition of nitric oxide synthase activity is beneficial. Certain novel compounds of formula (Ia) and pharmaceutically acceptable salts thereof, and enantiomers and racemates thereof are disclosed; together with processes for their preparation, compositions containing them and their use in therapy. The compounds of formulae (I) and (Ia) are inhibitors of the enzyme nitric oxide synthase and are thereby particularly useful in the treatment or prophylaxis of inflammatory disease.
    Type: Grant
    Filed: February 20, 2001
    Date of Patent: May 3, 2005
    Assignee: AstraZeneca AB
    Inventors: David Cheshire, Stephen Connolly, David Cox, Peter Hamley, Antonio Mete, Austen Pimm
  • Adamantane derivatives
    Patent number: 6881754
    Abstract: The invention provides adamantane derivatives of formula (I), a process for their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions, and their use in therapy. In formula (I) D represents CH2 or CH2CH2, E represents C(O)NH or NHC(O) and R3 represents a group of formula (I).
    Type: Grant
    Filed: December 12, 2000
    Date of Patent: April 19, 2005
    Assignee: AstraZeneca AB
    Inventors: Lilian Alcaraz, Moya Caffrey, Mark Furber, Timothy Luker, Michael Mortimore, Austen Pimm, Philip Thorne, Paul Willis
  • Adamantane derivatives
    Publication number: 20050049303
    Abstract: The invention provides adamantane derivatives of formula (I), a process for their preparation, pharmaceutical compositions containing them, a process for preparing the pharmaceutical compositions, and their use in therapy. In formula (I) D represents CH2 or CH2CH2, E represents C(O)NH or NHC(O) and R3 represents a group of formula (I).
    Type: Application
    Filed: March 31, 2004
    Publication date: March 3, 2005
    Inventors: Lilian Alcaraz, Mark Furber, Michael Mortimore, Austen Pimm, Philip Thorne, Paul Willis