Abstract: Multispectral digitized images are provided by utilizing 2 or more spectral bands, providing images and information regarding a pigmented or other differentiated tissue sample at differing depths. The images are transformed to enhance morphological patterns characteristic of melanoma, such as the statistical properties of the pigment network, image texture or homogeneity, and the lesion reflectance, in order to provide information about lesion morphology at different depths. The images can also be processed and transformed to extract features such as blood volume saturation, oxygen saturation, or other characteristics that can be identified based on differential reflectance or absorption of light.

Abstract: Multispectral digitized images are provided by utilizing 2 or more spectral bands, providing images and information regarding a pigmented or other differentiated tissue sample at differing depths. The images are transformed to enhance morphological patterns characteristic of melanoma, such as the statistical properties of the pigment network, image texture or homogeneity, and the lesion reflectance, in order to provide information about lesion morphology at different depths. The images can also be processed and transformed to extract features such as blood volume saturation, oxygen saturation, or other characteristics that can be identified based on differential reflectance or absorption of light.