Patents by Inventor AVEO PHARMACEUTICALS, INC.

AVEO PHARMACEUTICALS, INC. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IDENTIFICATION OF MULTIGENE BIOMARKERS
    Publication number: 20130165343
    Abstract: Methods for identifying multigene biomarkers for predicting sensitivity or resistance to an anti-cancer drug of interest, or multigene cancer prognostic biomarkers are disclosed. The disclosed methods are based on the classification of the mammalian genome into 51 transcription clusters, i.e., non-overlapping, functionally relevant groups of genes whose intra-group transcript levels are highly correlated. Also disclosed are specific multigene biomarkers for predicting sensitivity or resistance to tivozanib, or rapamycin, and a specific multigene biomarker for determining breast cancer prognosis, all of which were identified using the methods disclosed herein.
    Type: Application
    Filed: February 25, 2013
    Publication date: June 27, 2013
    Applicant: AVEO Pharmaceuticals, Inc.
    Inventor: AVEO Pharmaceuticals, Inc.
  • IDENTIFICATION OF MULTIGENE BIOMARKERS
    Publication number: 20130165337
    Abstract: Methods for identifying multigene biomarkers for predicting sensitivity or resistance to an anti-cancer drug of interest, or multigene cancer prognostic biomarkers are disclosed. The disclosed methods are based on the classification of the mammalian genome into 51 transcription clusters, i.e., non-overlapping, functionally relevant groups of genes whose intra-group transcript levels are highly correlated. Also disclosed are specific multigene biomarkers for predicting sensitivity or resistance to tivozanib, or rapamycin, and a specific multigene biomarker for determining breast cancer prognosis, all of which were identified using the methods disclosed herein.
    Type: Application
    Filed: November 5, 2012
    Publication date: June 27, 2013
    Applicant: AVEO PHARMACEUTICALS, INC.
    Inventor: AVEO PHARMACEUTICALS, INC.