Abstract: A continuous (multi-)analyte sensor device is provided, comprising a (multi-)analyte sensor operably coupled to a signal transducer, the (multi-)analyte sensor comprising at least one membrane, the least one membrane comprising a least one first transducing element, and at least one of a mediator and/or a regenerative cofactor.

Abstract: Various embodiments disclosed relate to analyte sensor configurations. The present disclosure can include planar analyte sensors or coaxial analyte sensors. The planar analyte sensors can include one or more insulating and conductive layers and a substrate layered on each other. The coaxial analyte sensors can include one or more co-extruded wire electrodes with a substrate. The continuous analyte monitoring systems discussed herein can be configured to monitor one or more analytes to provide predictive and real-time health data and benefits.

Abstract: An augmented analyte monitoring system is described. The augmented analyte monitoring system includes a wearable analyte monitoring device that includes a transmitter and an analyte sensor to obtain analyte data of a user, and an analyte augmentation wearable that includes one or more sensors (e.g., physical and/or biochemical sensors) to obtain additional physiological data for augmenting the analyte data of the user. The analyte augmentation wearable is communicably coupled to the wearable analyte monitoring device. The augmented analyte monitoring system further includes a sensor hub implemented at a computing device to obtain a data packet containing both the analyte data and the additional physiological data from at least one of the wearable analyte monitoring device or the analyte augmentation wearable, and augment the analyte data by storing the analyte data in association with the additional physiological data.

Abstract: A composite material for detecting and measuring levels of analytes and target molecules in biological fluid and tissue is disclosed herein. This composite material is constructed from a porous mesh sheet that is coated with a signal emitting material and is impregnated with target detecting molecules mixed inside one or multiple polymer mixtures. The geometry and configuration of different constituents can provide high efficiency of signals, the ability to measure multiple signals, small dimensions, fast response to changes, long storage lifetimes, controlled diffusional and mechanical properties, as well as easy industrial manufacturability. The composite material can be used in many sensing applications including optical or electrochemical continuous biosensing such as continuous glucose and lactate monitors.

Abstract: Embodiments describe a light-based medical device that uses light to luminesce tissue, and collect the reflected light, to perform analysis on the reflection characteristics in real-time to detect the type of surrounding tissue as well deeper tissue in the trajectory of the luminescence. Such device can be incorporated inside needles, catheters, tubes or piercing or biopsy tools, surgical blades, surgical tweezers, and so on, to direct their insertions and operations in specific zones. Importantly, because of the easy-to-use design, embodiments can be used without the need of highly trained personnel or expensive hospital equipment. Therefore, embodiments can be utilized in emergency situations that require fast responses, performed in ERs, moving vehicles, ambulances, and battlefields.