Abstract: An exemplary embodiment of the present disclosure provides systems and methods for non-invasively measuring blood pressure, the system and methods comprise a wearable device having a first surface, a first sensor positioned on the first surface of the wearable device, the first sensor configured to receive a first signal, wherein the first signal is indicative of a first blood-volume change in a first vessel of a subject, a second sensor positioned within the wearable device, the second sensor configured to receive a second signal, wherein the second signal is indicative of a cardiac mechanical motion of the subject, and a processor positioned within the wearable device, the processor configured to generate an output based at least on the first signal and the second signal, the output representing a blood pressure measurement of the subject.