Abstract: The present invention provides an oral dispersible film for donepezil hydrochloride. The film is a bilayer structure containing a drug layer containing 45-75% w/w donepezil hydrochloride and a backing layer without donepezil hydrochloride. The present oral film retains donepezil hydrochloride in a crystal form and minimizes impurity generation. The oral film contains a selected hydrophobic material to improve the drug stability and minimize the drug solubility.

Abstract: The present disclosure provides a method of facilitating streaming of events. Further, the method include receiving one or more sensor data. Further, the one or more sensors may be configured for generating the one or more sensor data by capturing one or more events. Further, the method include analyzing the one or more sensor data, generating one or more event representation data representing a virtual reconstruction of the one or more events based on the analyzing, processing the one or more event representation data, generating one or more streamable data for streaming the one or more events based on the processing, storing the one or more streamable data, and transmitting the one or more streamable data to one or more client devices.

Abstract: A method and system for automatically selecting a vehicle trajectory for an autonomous vehicle that is maximally compatible with all possible outcomes associated with the various multiple predictions for agents in the environment. The system includes an architecture with a model predictive unit, a speed planner, and a path planner.

Abstract: Aspects of the present disclosure relate to real-time masking of sensitive information in content shared during a screen share session of a video call. Aspects include determining a first computing device on the video call has accepted a request for the screen share session from a second computing device on the video call. Aspects include, in response to the determining, adjusting a frame rate of a video stream depicting content displayed on a display of the first computing device. Aspects include processing a video frame of a plurality of video frames included in the video stream to identify sensitive information depicted in the video frame. Aspects include modifying the video frame to mask the sensitive information. Aspects include transmitting the modified video frame to the second computing device for viewing on a display of the second computing device.

Abstract: Aspects of the present disclosure relate to real-time masking of sensitive information in content shared during a screen share session of a video call. Aspects include determining a first computing device on the video call has accepted a request for the screen share session from a second computing device on the video call. Aspects include, in response to the determining, adjusting a parameter of a video stream depicting content displayed on a display of the first computing device. Aspects include processing a video frame of a plurality of video frames included in the video stream to identify sensitive information depicted in the video frame. Aspects include modifying the video frame to mask the sensitive information. Aspects include transmitting the modified video frame to the second computing device for viewing on a display of the second computing device.

Abstract: According to one aspect, local path planning may be achieved using a sensor, a memory, a processor, a controller, and an actuator. The sensor may detect two or more objects within an operating environment. The memory may store one or more instructions. The processor may execute one or more of the instructions stored on the memory to perform one or more acts, actions, and/or steps. The processor may generate bounding box information for bounding boxes of the two or more objects. The processor may generate an envelop graph structure based on the bounding box information. The processor may generate a local path planning trajectory from a start region to a goal region within the envelop graph structure based on a cost function and the envelop graph structure. The controller may control the actuator to execute the local path planning trajectory for the autonomous vehicle.

Abstract: According to one aspect, local path planning may include classifying an object within an operating environment as an upper bound object, a lower bound object, or infeasible based on a distance between a bounding box associated with the object and an upper environment feature, a distance between the bounding box associated with the object and a lower environment feature, and a cost function, generating a boundary associated with the object and the upper environment feature or the lower environment feature based on the classification of the object and boundary points of the bounding box associated with the object, and generating a local path planning trajectory for a vehicle based on the classification of the object, the boundary associated with the object, and transforming a kinematic model from a space-time domain to a space-only domain.

Abstract: Aspects of the present disclosure relate to real-time masking of sensitive information in content shared during a screen share session of a video call. Aspects include determining a first computing device on the video call has accepted a request for the screen share session from a second computing device on the video call. Aspects include, in response to the determining, adjusting a parameter of a video stream depicting content displayed on a display of the first computing device. Aspects include processing a video frame of a plurality of video frames included in the video stream to identify sensitive information depicted in the video frame. Aspects include modifying the video frame to mask the sensitive information. Aspects include transmitting the modified video frame to the second computing device for viewing on a display of the second computing device.

Abstract: A method for generating an audio signal includes capturing, during a traversal event, at least one audio stream associated with one or more of a content, an ambient audio stream, and at least one user interface (UI) frame; obtaining a set of audio features, and obtaining one or more of UI elements; determining an audio gain based on a prioritization and a weighted average of the extracted set of audio features; determining a UI context based on a UI contextual score of the extracted one or more UI elements; obtaining an audio map comprising at least one biased audio file and at least one unbiased audio file; and obtaining the audio signal based on a priority order assigned to the at least one biased audio file and the at least one unbiased audio file associated with the audio map.

Abstract: A method for modifying audio content including: determining a crisp emotion value defining an audio object emotion, for each audio object among a plurality of audio objects associated with an audio content, the plurality of audio objects being at least some of a total number of audio objects associated with the audio content; determining a composition factor representing one or more emotions, among a plurality of emotions, in the crisp emotion value of each audio object; calculating a probability of a user associating with each of the one or more emotions represented in the composition factor; and calculating a priority value for each audio object based on the probability of the user associating with the each of the one or more emotions represented in the composition factor of each audio object and the composition factor of each audio object.

Abstract: The present invention provides an oral dispersible film for donepezil hydrochloride. The film is a bilayer structure containing a drug layer containing 45-75% w/w donepezil hydrochloride and a backing layer without donepezil hydrochloride. The present oral film retains donepezil hydrochloride in a crystal form and minimizes impurity generation. The oral film contains a selected hydrophobic material to improve the drug stability and minimize the drug solubility.

Abstract: A system for intelligent audio rendering using speaker nodes is provided. A source device determines a spatial location and speaker capability of one or more speaker nodes based on information embedded in a corresponding node of each of the one or more media devices, selects a first speaker most suitable for each audio channel based on the speaker capability and the spatial location of each of the one or more speakers, generates speaker profiles for the one or more speakers, maps an audio channel to each of the one or more speakers based on a speaker profile corresponding to each of the one or more speakers, estimates a media path between the source device and each of the one or more speakers, detects a change in the estimated media path, renders an audio on the one or more speakers based on the speaker profiles and the changes in the media paths corresponding to each of the one or more speakers in real-time.

Abstract: The present invention provides an oral patch for localized treatment of mouth ulcers containing combination of tetracaine and triamcinolone as active drugs. The patch is a bilayer structure containing a drug layer with amorphous tetracaine hydrochloride and amorphous triamcinolone acetonide and a water-soluble backing layer without a drug. The oral patch with combination of drugs has improved efficacy over each individual drug. The drug layer comprises 3-20% by weight of amorphous tetracaine hydrochloride, or a pharmaceutical acceptable salt thereof, 0.1-2.0% by weight of amorphous triamcinolone acetonide or a pharmaceutical acceptable salt thereof, 20-95% by weight of a first film-forming material, 1-12% by weight of an adhesive, 1-20% by weight of one or more cooling agent, and optionally 1-12% by weight of a plasticizer. The backing layer comprises 70-95% by weight of one or more film-forming agents, 2-10% by weight of a plasticizer and optionally 1-8% by weight of a flavoring agent.

Abstract: A drive system includes a prime mover that provides an input, and an output system that is driven by the input. A torque transfer system is coupled between the prime mover and the output system. The torque transfer system includes two gear planes. Each of the gear planes includes a pair of gear meshes, and each of the pair of gear meshes has a floating structure.

Abstract: The present invention provides an oral transmucosal film for delivering agomelatine through the buccal mucosa or sublingual mucosa. The film is a bilayer structure containing a mucoadhesive layer with amorphous agomelatine and a water-soluble backing layer without agomelatine. The film has improved bioavailability and improved palatability. The mucoadhesive layer comprises comprising 0.1%-40% by weight of amorphous agomelatine, or a pharmaceutical acceptable salt thereof, 50-98% by weight of a first film-forming material, 0.5-20% by weight of an oil phase excipient, and 0.5-17% by weight of a surfactant. The backing layer comprises 60-100% (w/w) of one or more film-forming agents.

Abstract: The present invention provides an oral transmucosal film for delivering tadalafil through the buccal mucosa or sublingual mucosa. The film is a single layer structure containing amorphous tadalafil, one or more solubilizers, one or more penetration enhancers, and one or more adhesives to deliver the drug through a transmucosal route. Comparing with an oral tadalafil tablet, the present oral transmucosal film provides improved absorption rate and Tmax. The oral transmucosal film comprises 5%-60% by weight of amorphous tadalafil, 25-96% by weight of a film-forming material, 1-20% by weight of a solubilizer, 0.5-10% by weight of a penetration enhancer, and 1-15% by weight of an adhesive.

Abstract: Systems and methods forecast inbound telecommunications, and more particularly, analyze real-time and historical call center data, and apply a forecasting model to the data in order to predict inbound call volume. These systems and methods employ tools that manipulate call center data and generate visual representations of metrics pertaining to forecasting call center data via a dashboard.

Abstract: Systems and methods are provided for pumps that deliver optimized torque characteristics and volumetric efficiency. A system includes a housing defining a surface and a rotor defining a face. A face clearance is defined between the face and the surface. The face clearance is variable in magnitude and determinative of target performance characteristics of the pump system. The housing is made of a material selected to have a thermal expansion characteristic and the rotor is made of a second material selected to have another thermal expansion characteristic. The thermal expansion characteristics deliver the target performance characteristics of the pump system.

Abstract: Motor driven systems with optimized performance and efficiency are provided. A drive system includes a motor and a gear system coupled with the motor by a shaft. The gear system includes a pair of input gears disposed on the shaft, and a pair of transfer shafts including transfer gears meshing with the input gears. The gear system is configured to cancel axial, radial and/or tangential forces for minimized net force at the shaft.

Abstract: Disclosed are systems and methods for forecasting inbound telecommunications, and more particularly, for analyzing real-time and historical call center data, and applying a forecasting model to said data in order to predict inbound call volume. Additionally, tools are disclosed for manipulating call center data and generating visual representations of metrics pertaining to forecasting call center data via a dashboard.