Abstract: A method of detecting iron-related entities in a region of interest, is disclosed. The method may comprise: receiving at least two Magnetic Resonance Imaging (MRI) signals from each of at least two different locations in the region of interest; calculating at least four MRI parameters from the MRI signals; and determining a presence of at least two different iron-related entities in the region of interest based on the at least four MRI parameters.

Abstract: A system and method of non-invasive diagnosis of a condition in a subject may include obtaining, from a medical scanning device, a three-dimensional (3D) scan of the subject, said scan comprising a plurality of quantitative or semi-quantitative voxel values; segmenting the scan, to obtain a segmented region of interest (ROI) of the subject; performing a singular value decomposition (SVD) of the ROI, to determine at least one axis of the ROI in the SVD space; and analyzing the voxel values along the at least one axis, to diagnose a condition of the subject. Analysis of the voxel values may include calculating a quantitative function of voxel values along the at least one axis; comparing the calculated quantitative function to a reference quantitative function; and diagnosing or predicting a condition of the subject, based on the comparison.

Abstract: In accordance with some embodiments of the invention there is provided a method for quantification of molecular composition of a scanned tissue based on an MRI signal including receiving qMRI (quantitative MRI) data from a tissue scan, the qMRI data comprising at least a first and a second parameter, wherein said first parameter is a non-water fraction of the scanned tissue, calculating a dependency of the second qMRI parameter on a non-water fraction of the scanned tissue, and quantifying a molecular composition of the scanned tissue based on the calculation. In accordance with some embodiments of the invention there is provided a computer program product comprising a non-transitory computer-readable storage medium having program code embodied therewith, the program code executable by at least one hardware processor to carry out the method.

Abstract: The present invention provides methods to detect degenerative processes and abnormalities in soft tissues at high spatial resolution, high signal-to-noise ratio and short scanning times, based on quantitative tissue properties. These methods might provide a useful tool to detect and assess abnormalities in soft tissues and to monitor disease progression.