Abstract: Various embodiments of the present technology generally relate to closed loop deep brain stimulation based on inferred sleep stage from physiological data using machine learning classifiers. Some embodiments, for example, may use subthalamic nucleus (STN) deep brain stimulation (DBS) to treat advanced Parkinsons Disease motor symptoms and improve sleep by identifying sleep stages commensurate with clinician-scored polysomnography (PSG). The DBS may be adapted to include novel artificial neural network (ANN) that triggers targeted stimulation in response to inferred sleep state from STN local field potentials (LFPs) recorded from implanted DBS electrodes. A feedforward neural network can be trained to prospectively identify sleep stage with PSG-level accuracy. In some embodiments, the machine learning model stored within the DB S may also adapt stimulation during specific sleep stages to treat targeted sleep deficits.

Abstract: An adapter to be used to position and restrain a patient's head movement during magnetic resonance imaging (MRI), computed tomography (CT) imaging, positron emission tomography (PET) imaging, X-ray imaging or other imaging or medical procedures. The adapter has a high degree of adjustability and modularity. The adapter can be fitted to a patient quickly and comfortably by offering translational, rotational and height adjustment during the fitting procedure, thereby reducing the overall time for the MRI. The adapter includes a base, one or more attachment members to selectively affix the base to an imaging table, a pair of upwardly extending spaced-apart supports attached to the base, a stabilizer frame rotatably attached to the pair of supports, and a locking mechanism to selectively prevent rotation of the frame attached to the pair of supports.

Abstract: An adapter to be used to position and restrain a patient's head movement during magnetic resonance imaging (MRI), computed tomography (CT) imaging, positron emission tomography (PET) imaging, X-ray imaging or other imaging or medical procedures. The adapter has a high degree of adjustability and modularity. The adapter can be fitted to a patient quickly and comfortably by offering translational, rotational and height adjustment during the fitting procedure, thereby reducing the overall time for the MRI. The adapter includes a base, one or more attachment members to selectively affix the base to an imaging table, a pair of upwardly extending spaced-apart supports attached to the base, a stabilizer frame rotatably attached to the pair of supports, and a locking mechanism to selectively prevent rotation of the frame attached to the pair of supports.