Patents by Inventor Avner Ramu

Avner Ramu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190350900
    Abstract: A new indication for the Warfarin family of drugs is described. In patients suffering from chronic periodontitis, continued systemic medication with Warfarin causes a significant reduction in their chronic periodontitis, including reduction in the frequency and severity of gingival inflammation occurrences, and significant decrease in the buildup of dental plaque and tartar. Delivery of Warfarin or its analogs directly to the oral fluid using toothpaste, mouthwash, chewing gum, dental floss, toothbrush, pill, and other forms are described to reduce chronic periodontitis, dental plaque, and dental tartar.
    Type: Application
    Filed: August 3, 2019
    Publication date: November 21, 2019
    Inventor: Avner Ramu
  • Patent number: 10405789
    Abstract: An apparatus for determining the volume of urine in a human bladder is described. The apparatus uses light to determine the length of a flexible tube attached vertically to the outside of the bladder, and converts the length into a fullness value that is transmitted to an external device that notifies a user about the state of the bladder.
    Type: Grant
    Filed: July 7, 2017
    Date of Patent: September 10, 2019
    Inventors: Avner Ramu, Nehemia Hampel
  • Patent number: 10383845
    Abstract: A new indication for the Warfarin family of drugs is described. In patients suffering from chronic periodontitis, continued systemic medication with Warfarin causes a significant reduction in their chronic periodontitis, including reduction in the frequency and severity of gingival inflammation occurrences, and significant decrease in the buildup of dental plaque and tartar. Delivery of Warfarin or its analogs directly to the oral fluid using toothpaste, mouthwash, chewing gum, dental floss, toothbrush, pill, and other forms are described to reduce chronic periodontitis, dental plaque, and dental tartar.
    Type: Grant
    Filed: May 4, 2018
    Date of Patent: August 20, 2019
    Inventor: Avner Ramu
  • Publication number: 20180318253
    Abstract: A new indication for the Warfarin family of drugs is described. In patients suffering from chronic periodontitis, continued systemic medication with Warfarin causes a significant reduction in their chronic periodontitis, including reduction in the frequency and severity of gingival inflammation occurrences, and significant decrease in the buildup of dental plaque and tartar. Delivery of Warfarin or its analogs directly to the oral fluid using toothpaste, mouthwash, chewing gum, dental floss, toothbrush, pill, and other forms are described to reduce chronic periodontitis, dental plaque, and dental tartar.
    Type: Application
    Filed: May 4, 2018
    Publication date: November 8, 2018
    Inventor: Avner Ramu
  • Publication number: 20180008185
    Abstract: An apparatus for determining the volume of urine in a human bladder is described. The apparatus uses light to determine the length of a flexible tube attached vertically to the outside of the bladder, and converts the length into a fullness value that is transmitted to an external device that notifies a user about the state of the bladder.
    Type: Application
    Filed: July 7, 2017
    Publication date: January 11, 2018
    Inventors: Avner Ramu, Nehemia Hampel
  • Publication number: 20010056085
    Abstract: The present invention relates to methods of treating, as well as preventing extravasation injury. In particular, the present invention pertains to photochemotherapeutic methods of prophylaxis and/or treatment of extravasation injury induced by vesicant antineoplastic drugs and other pharmaceutical formulations. In accordance with the present invention, extravasation injury is prevented or minimized by the coadministration of photoinactivation inducing compounds in a formulation comprising a vesicant antineoplastic or other pharmaceutical formulation, and subsequently exposing the injection or infusion site to photoexciting light.
    Type: Application
    Filed: March 9, 2001
    Publication date: December 27, 2001
    Inventor: Avner Ramu
  • Patent number: 5780446
    Abstract: The present invention relates to methods of treating, as well as preventing extravasation injury. In particular, the present invention pertains to photochemotherapeutic methods of prophylaxis and/or treatment of extravasation injury induced by vesicant antineoplastic drugs and other pharmaceutical formulations. In accordance with the present invention, extravasation injury is prevented or minimized by the coadministration of photoinactivation inducing compounds in a formulation comprising a vesicant antineoplastic or other pharmaceutical formulation, and subsequently exposing the injection or infusion site to photoexciting light.
    Type: Grant
    Filed: July 9, 1996
    Date of Patent: July 14, 1998
    Assignee: Baylor College of Medicine
    Inventor: Avner Ramu
  • Patent number: 5190946
    Abstract: Compounds of formula ##STR1## wherein R and R.sup.3, which may be the same or different, each is hydrogen, an alkyl group containing 1 to 5 carbon atoms, or an optionally substituted aryl or aralkyl group, substituents being selected from the group consisting of halogen, alkoxy and alkyl groups containing 1 to 5 carbon atoms, said alkyl groups in turn being optionally halo-substituted; R.sup.1 and R.sup.2, which may be the same or different, each is hydrogen, an alkyl group containing 1 to 5 carbon atoms, or an optionally substituted aryl or aralkyl group, substituents being as indicated above or R.sup.1 and R.sup.2 taken together are an alkylene group containing 2 or 3 carbon atoms; m and p, which may be the same or different each is a number from 0 to 3; n is the number 2 or 3; and X is a group of the formula R.sub.x.sup.4 --CO--, R.sub.x.sup.4 --COO--, R.sub.x.sup.4 --CONH--, R.sub.x.sup.4 --NHCO--, or R.sub.x.sup.4 --O-- and Y is a group of formula R.sub.y.sup.4 --CO--, R.sub.y.sup.4 --COO--, R.sub.y.sup.
    Type: Grant
    Filed: February 12, 1991
    Date of Patent: March 2, 1993
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Avner Ramu, Karel Valter
  • Patent number: 5160727
    Abstract: A method for sensitizing cancer cells which have become resistant to treatment with one or more anticancer agents which comprises treating said cells with a quinazolinedione compound.
    Type: Grant
    Filed: March 21, 1990
    Date of Patent: November 3, 1992
    Assignees: Warner-Lambert Company, Hadasit Medical Research Services and Development
    Inventors: Wayne Klohs, Avner Ramu