Patents by Inventor Axel F. Brisken

Axel F. Brisken has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210146143
    Abstract: Receiver-stimulator with folded or rolled up assembly of piezoelectric components, causing the receiver-stimulator to operate with a high degree of isotropy are disclosed. The receiver-stimulator comprises piezoelectric components, rectifier circuitry, and at least two stimulation electrodes. Isotropy allows the receiver-stimulator to be implanted with less concern regarding the orientation relative the transmitted acoustic field from an acoustic energy source.
    Type: Application
    Filed: September 24, 2020
    Publication date: May 20, 2021
    Inventors: David F. Moore, Paul Mohr, N. Parker Willis, Axel F. Brisken
  • Patent number: 10806938
    Abstract: Receiver-stimulator with folded or rolled up assembly of piezoelectric components, causing the receiver-stimulator to operate with a high degree of isotropy are disclosed. The receiver-stimulator comprises piezoelectric components, rectifier circuitry, and at least two stimulation electrodes. Isotropy allows the receiver-stimulator to be implanted with less concern regarding the orientation relative the transmitted acoustic field from an acoustic energy source.
    Type: Grant
    Filed: July 31, 2018
    Date of Patent: October 20, 2020
    Assignee: EBR Systems, Inc.
    Inventors: David F. Moore, Paul Mohr, N. Parker Willis, Axel F. Brisken
  • Publication number: 20200230426
    Abstract: Method and systems for optimizing acoustic energy transmission in implantable devices are disclosed. Transducer elements transmit acoustic locator signals towards a receiver assembly, and the receiver responds with a location signal. The location signal can reveal information related to the location of the receiver and the efficiency of the transmitted acoustic beam received by the receiver. This information enables the transmitter to target the receiver and optimize the acoustic energy transfer between the transmitter and the receiver. The energy can be used for therapeutic purposes, for example, stimulating tissue or for diagnostic purposes.
    Type: Application
    Filed: October 15, 2019
    Publication date: July 23, 2020
    Inventors: N. Parker Willis, Axel F. Brisken, Mark W. Cowan, Michael Pare, Robert Fowler, James Brennan
  • Patent number: 10512785
    Abstract: A controller-transmitter transmits acoustic energy through the body to an implanted acoustic receiver-stimulator. The receiver-stimulator converts the acoustic energy into electrical energy and delivers the electrical energy to tissue using an electrode assembly. The receiver-stimulator limits the output voltage delivered to the tissue to a predetermined maximum output voltage. In the presence of interfering acoustic energy sources output voltages are thereby limited prior to being delivered to the tissue. Furthermore, the controller-transmitter estimates the output voltage that is delivered to the tissue by the implanted receiver-stimulator. The controller-transmitter measures a query spike voltage resulting from the electrical energy delivered to the tissue by the receiver-stimulator, and computes a ratio of the predetermined maximum output voltage and a maximum query spike voltage. The maximum query spike voltage is computed by detecting a query spike voltage plateau.
    Type: Grant
    Filed: January 17, 2019
    Date of Patent: December 24, 2019
    Assignee: EBR Systems, Inc.
    Inventors: David F. Moore, Paul Mohr, N. Parker Willis, Axel F. Brisken
  • Publication number: 20190351226
    Abstract: The present invention relies on a controller-transmitter device to deliver ultrasound energy into cardiac tissue in order to directly improve cardiac function and/or to energize one or more implanted receiver-stimulator devices that transduce the ultrasound energy to electrical energy to perform excitatory and/or non-excitatory treatments for heart failure. The acoustic energy can be applied as a single burst or as multiple bursts.
    Type: Application
    Filed: January 16, 2019
    Publication date: November 21, 2019
    Inventors: Debra S. Echt, Richard E. Riley, Mark W. Cowan, Axel F. Brisken
  • Publication number: 20190336776
    Abstract: Systems and methods are disclosed to stimulate tissue to treat medical conditions involving tissues such as the bone, spine, stomach, nerves, brain and the cochlea. The disclosed invention uses electrical stimulation of the tissue, where vibrational (or acoustic) energy from a source is received by an implanted device and converted to electrical energy and the converted electrical energy is used by implanted electrodes to stimulate the pre-determined tissue sites. The vibrational energy is generated by a controller-transmitter, which could be either implanted or located externally. The vibrational energy is received by a receiver-stimulator, which could be located at or close to the stimulation site.
    Type: Application
    Filed: October 29, 2018
    Publication date: November 7, 2019
    Applicant: EBR Systems, Inc.
    Inventors: Mark W. Cowan, Richard E. Riley, Axel F. Brisken, Debra S. Echt
  • Patent number: 10456588
    Abstract: Method and systems for optimizing acoustic energy transmission in implantable devices are disclosed. Transducer elements transmit acoustic locator signals towards a receiver assembly, and the receiver responds with a location signal. The location signal can reveal information related to the location of the receiver and the efficiency of the transmitted acoustic beam received by the receiver. This information enables the transmitter to target the receiver and optimize the acoustic energy transfer between the transmitter and the receiver. The energy can be used for therapeutic purposes, for example, stimulating tissue or for diagnostic purposes.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: October 29, 2019
    Assignee: EBR Systems, Inc.
    Inventors: N. Parker Willis, Axel F. Brisken, Mark W. Cowan, Michael Pare, Robert Fowler, James Brennan
  • Publication number: 20190151667
    Abstract: A controller-transmitter transmits acoustic energy through the body to an implanted acoustic receiver-stimulator. The receiver-stimulator converts the acoustic energy into electrical energy and delivers the electrical energy to tissue using an electrode assembly. The receiver-stimulator limits the output voltage delivered to the tissue to a predetermined maximum output voltage. In the presence of interfering acoustic energy sources output voltages are thereby limited prior to being delivered to the tissue. Furthermore, the controller-transmitter estimates the output voltage that is delivered to the tissue by the implanted receiver-stimulator. The controller-transmitter measures a query spike voltage resulting from the electrical energy delivered to the tissue by the receiver-stimulator, and computes a ratio of the predetermined maximum output voltage and a maximum query spike voltage. The maximum query spike voltage is computed by detecting a query spike voltage plateau.
    Type: Application
    Filed: January 17, 2019
    Publication date: May 23, 2019
    Inventors: David F. Moore, Paul Mohr, N. Parker Willis, Axel F. Brisken
  • Patent number: 10207115
    Abstract: The present invention relies on a controller-transmitter device to deliver ultrasound energy into cardiac tissue in order to directly improve cardiac function and/or to energize one or more implanted receiver-stimulator devices that transduce the ultrasound energy to electrical energy to perform excitatory and/or non-excitatory treatments for heart failure. The acoustic energy can be applied as a single burst or as multiple bursts.
    Type: Grant
    Filed: April 26, 2016
    Date of Patent: February 19, 2019
    Assignee: EBR Systems, Inc.
    Inventors: Debra S. Echt, Richard E. Riley, Mark W. Cowan, Axel F. Brisken
  • Publication number: 20180353763
    Abstract: Method and systems for optimizing acoustic energy transmission in implantable devices are disclosed. Transducer elements transmit acoustic locator signals towards a receiver assembly, and the receiver responds with a location signal. The location signal can reveal information related to the location of the receiver and the efficiency of the transmitted acoustic beam received by the receiver. This information enables the transmitter to target the receiver and optimize the acoustic energy transfer between the transmitter and the receiver. The energy can be used for therapeutic purposes, for example, stimulating tissue or for diagnostic purposes.
    Type: Application
    Filed: August 21, 2018
    Publication date: December 13, 2018
    Applicant: EBR Systems, Inc.
    Inventors: N. Parker Willis, Axel F. Brisken, Mark W. Cowan, Michael Pare, Robert Fowler, James Brennan
  • Publication number: 20180345026
    Abstract: Receiver-stimulator with folded or rolled up assembly of piezoelectric components, causing the receiver-stimulator to operate with a high degree of isotropy are disclosed. The receiver-stimulator comprises piezoelectric components, rectifier circuitry, and at least two stimulation electrodes. Isotropy allows the receiver-stimulator to be implanted with less concern regarding the orientation relative the transmitted acoustic field from an acoustic energy source.
    Type: Application
    Filed: July 31, 2018
    Publication date: December 6, 2018
    Applicant: EBR Systems, Inc.
    Inventors: David F. Moore, Paul Mohr, N. Parker Willis, Axel F. Brisken
  • Patent number: 10143850
    Abstract: Systems and methods are disclosed to stimulate tissue to treat medical conditions involving tissues such as the bone, spine, stomach, nerves, brain and the cochlea. The disclosed invention uses electrical stimulation of the tissue, where vibrational (or acoustic) energy from a source is received by an implanted device and converted to electrical energy and the converted electrical energy is used by implanted electrodes to stimulate the pre-determined tissue sites. The vibrational energy is generated by a controller-transmitter, which could be either implanted or located externally. The vibrational energy is received by a receiver-stimulator, which could be located at or close to the stimulation site.
    Type: Grant
    Filed: August 29, 2016
    Date of Patent: December 4, 2018
    Assignee: EBR Systems, Inc.
    Inventors: Mark W. Cowan, Richard E. Riley, Axel F. Brisken, Debra S. Echt
  • Patent number: 10080903
    Abstract: Method and systems for optimizing acoustic energy transmission in implantable devices are disclosed. Transducer elements transmit acoustic locator signals towards a receiver assembly, and the receiver responds with a location signal. The location signal can reveal information related to the location of the receiver and the efficiency of the transmitted acoustic beam received by the receiver. This information enables the transmitter to target the receiver and optimize the acoustic energy transfer between the transmitter and the receiver. The energy can be used for therapeutic purposes, for example, stimulating tissue or for diagnostic purposes.
    Type: Grant
    Filed: March 20, 2014
    Date of Patent: September 25, 2018
    Assignee: EBR SYSTEMS, INC.
    Inventors: N. Parker Willis, Axel F. Brisken, Mark W. Cowan, Michael Pare, Robert Fowler, James Brennan
  • Patent number: 10052493
    Abstract: Receiver-stimulator with folded or rolled up assembly of piezoelectric components, causing the receiver-stimulator to operate with a high degree of isotropy are disclosed. The receiver-stimulator comprises piezoelectric components, rectifier circuitry, and at least two stimulation electrodes. Isotropy allows the receiver-stimulator to be implanted with less concern regarding the orientation relative the transmitted acoustic field from an acoustic energy source.
    Type: Grant
    Filed: April 25, 2016
    Date of Patent: August 21, 2018
    Assignee: EBR Systems, Inc.
    Inventors: David F. Moore, Paul Mohr, N. Parker Willis, Axel F. Brisken
  • Publication number: 20160367823
    Abstract: Systems and methods are disclosed to stimulate tissue to treat medical conditions involving tissues such as the bone, spine, stomach, nerves, brain and the cochlea. The disclosed invention uses electrical stimulation of the tissue, where vibrational (or acoustic) energy from a source is received by an implanted device and converted to electrical energy and the converted electrical energy is used by implanted electrodes to stimulate the pre-determined tissue sites. The vibrational energy is generated by a controller-transmitter, which could be either implanted or located externally. The vibrational energy is received by a receiver-stimulator, which could be located at or close to the stimulation site.
    Type: Application
    Filed: August 29, 2016
    Publication date: December 22, 2016
    Inventors: Mark W. Cowan, Richard E. Riley, Axel F. Brisken, Debra S. Echt
  • Publication number: 20160310749
    Abstract: Receiver-stimulator with folded or rolled up assembly of piezoelectric components, causing the receiver-stimulator to operate with a high degree of isotropy are disclosed. The receiver-stimulator comprises piezoelectric components, rectifier circuitry, and at least two stimulation electrodes. Isotropy allows the receiver-stimulator to be implanted with less concern regarding the orientation relative the transmitted acoustic field from an acoustic energy source.
    Type: Application
    Filed: April 25, 2016
    Publication date: October 27, 2016
    Inventors: David F. Moore, Paul Mohr, N. Parker Willis, Axel F. Brisken
  • Patent number: 9452286
    Abstract: Systems and methods are disclosed to stimulate tissue to treat medical conditions involving tissues such as the bone, spine, stomach, nerves, brain and the cochlea. The disclosed invention uses electrical stimulation of the tissue, where vibrational (or acoustic) energy from a source is received by an implanted device and converted to electrical energy and the converted electrical energy is used by implanted electrodes to stimulate the pre-determined tissue sites. The vibrational energy is generated by a controller-transmitter, which could be either implanted or located externally. The vibrational energy is received by a receiver-stimulator, which could be located at or close to the stimulation site.
    Type: Grant
    Filed: June 20, 2013
    Date of Patent: September 27, 2016
    Assignee: EBR Systems, Inc.
    Inventors: Mark W. Cowan, Richard E. Riley, Axel F. Brisken, Debra S. Echt
  • Publication number: 20160235976
    Abstract: The present invention relies on a controller-transmitter device to deliver ultrasound energy into cardiac tissue in order to directly improve cardiac function and/or to energize one or more implanted receiver-stimulator devices that transduce the ultrasound energy to electrical energy to perform excitatory and/or non-excitatory treatments for heart failure. The acoustic energy can be applied as a single burst or as multiple bursts.
    Type: Application
    Filed: April 26, 2016
    Publication date: August 18, 2016
    Inventors: Debra S. Echt, Richard E. Riley, Mark W. Cowan, Axel F. Brisken
  • Patent number: 9343654
    Abstract: Receiver-stimulator with folded or rolled up assembly of piezoelectric components, causing the receiver-stimulator to operate with a high degree of isotropy are disclosed. The receiver-stimulator comprises piezoelectric components, rectifier circuitry, and at least two stimulation electrodes. Isotropy allows the receiver-stimulator to be implanted with less concern regarding the orientation relative the transmitted acoustic field from an acoustic energy source.
    Type: Grant
    Filed: October 15, 2015
    Date of Patent: May 17, 2016
    Assignee: EBR Systems, Inc.
    Inventors: David F. Moore, Paul Mohr, N. Parker Willis, Axel F. Brisken
  • Patent number: 9333364
    Abstract: The present invention relies on a controller-transmitter device to deliver ultrasound energy into cardiac tissue in order to directly improve cardiac function and/or to energize one or more implanted receiver-stimulator devices that transduce the ultrasound energy to electrical energy to perform excitatory and/or non-excitatory treatments for heart failure. The acoustic energy can be applied as a single burst or as multiple bursts.
    Type: Grant
    Filed: July 1, 2010
    Date of Patent: May 10, 2016
    Assignee: EBR Systems, Inc.
    Inventors: Debra S. Echt, Richard E. Riley, Mark W. Cowan, Axel F. Brisken