Patents by Inventor Axel Paul
Axel Paul has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240131271Abstract: A drive train for a wind-up injection device is described. The drive train includes a torsional energy storage adapted to be loaded or unloaded by a rotatable element, a rotatable user handle, a rotationally driveable expelling mechanism adapted to expel the liquid drug, and a clutch element coupled with the torsional energy storage via the rotatable element and including a ratchet for maintaining the rotatable element at one of a number of discrete angular positions against the torque of the torsional energy storage. The clutch element is adapted to transmit the torque from the user handle to the torsional energy storage, or alternatively from the torsional energy storage to the expelling mechanism. The ratchet is switchable from one position to an adjacent position by a torque transmitted from the user handle to the torsional energy storage. The drive train is adapted to dampen torque peaks visco-elastically and/or visco-frictionally.Type: ApplicationFiled: December 8, 2023Publication date: April 25, 2024Inventors: Michael Jugl, Stefan Blancke, Axel Teucher, Ralph Donald Quentin Collings, James Robert Coop, James Anthony West, Stephen Francis Gilmore, Daniel David Higgins, Mark Digby Teucher, Anthony Paul Morris, Matthew Meredith Jones, William Geoffrey Arthur Marsh, Samuel Keir Steel
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Publication number: 20240065963Abstract: The instant disclosure generally relates to a multicomponent composition for coating mammalian or synthetic keratin material and textiles, the composition comprising a first and second components and a third component. The first and second components comprise first and second compounds respectively. Any one or more of the first, second and third components may also comprise pigment microparticles. The first, second and third compounds meld together on keratin material and textiles and especially on hair to form a coating that can be formulated to provide temporary coverage or provide permanent coverage. The multicomponent composition formed and set in situ as a solid linked coating ranges from ready removability to substantially permanent lastingness.Type: ApplicationFiled: July 26, 2023Publication date: February 29, 2024Inventors: Mathias Kurt HERRLEIN, Matija CRNE, Corinne MOHR, Graham Neil MCKELVEY, Simon Paul GODFREY, Axel MEYER, Petra BRAUN, Malte AFFLERBACH, Andrej GROSS, Michael A. BROOK, Yan WANG
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Patent number: 8466299Abstract: The process relates to a process for preparing delta-valerolactone (VLO) in the gas phase by catalytic dehydrogenation over at least two different catalysts.Type: GrantFiled: December 2, 2009Date of Patent: June 18, 2013Assignee: BASF SEInventors: Rolf Pinkos, Christophe Bauduin, Axel Paul, Gerhard Fritz, Hans Wagner
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Patent number: 8383866Abstract: The present invention relates to a process for preparing diols by hydrogenating a mixture comprising carboxylic acid, carboxylic anhydrides and/or carboxylic esters/lactones by means of a cobalt-comprising catalyst, wherein alkali metal and/or alkaline earth metal ions are added to the hydrogenation feed, excluding alkali metal and/or alkaline earth metal ions of mineral acids.Type: GrantFiled: November 23, 2010Date of Patent: February 26, 2013Assignee: BASF SEInventors: Rolf Pinkos, Axel Paul, Rolf-Hartmuth Fischer, Roman Dostalek
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Publication number: 20120071692Abstract: A process for preparing an aromatic amine by reacting a corresponding aromatic alcohol with an aminating agent selected from the group consisting of ammonia, primary amines and secondary amines, in the presence of hydrogen and a catalyst molding, at a temperature of from 60-300°. The catalyst molding comprises Zr, Pd and Pt and has an annular tablet form with an external diameter in the range from 2-6 mm, a height in the range from 1-4 mm and an internal diameter of from 1-5 mm or a topologically equivalent form with the same volume. Catalyst moldings comprising Zr, Pd and Pt are also provided. The catalyst molding has an annular tablet form with an external diameter in the range from 3-6 mm, a height in the range from 1-4 mm and an internal diameter of from 2-5 mm or a topologically equivalent form.Type: ApplicationFiled: September 16, 2011Publication date: March 22, 2012Applicant: BASF SEInventors: SEBASTIAN AHRENS, Christoph Mueller, Axel Paul, Martin Ernst, Nadja Pollmer, Johann-Peter Melder, Thomas Heidemann, Joachim-Thierry Anders, Bram Willem Hoffer
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Publication number: 20110237806Abstract: The process relates to a process for preparing delta-valerolactone (VLO) in the gas phase by catalytic dehydrogenation over at least two different catalysts.Type: ApplicationFiled: December 2, 2009Publication date: September 29, 2011Applicant: BASF SEInventors: Rolf Pinkos, Christophe Bauduin, Axel Paul, Gerhard Fritz, Hans Wagner
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Publication number: 20110124926Abstract: The present invention relates to a process for preparing diols by hydrogenating a mixture comprising carboxylic acid, carboxylic anhydrides and/or carboxylic esters/lactones by means of a cobalt-comprising catalyst, wherein alkali metal and/or alkaline earth metal ions are added to the hydrogenation feed, excluding alkali metal and/or alkaline earth metal ions of mineral acids.Type: ApplicationFiled: November 23, 2010Publication date: May 26, 2011Applicant: BASF SEInventors: Rolf PINKOS, Axel Paul, Rolf-Hartmuth Fischer, Roman Dostalek
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Publication number: 20110034706Abstract: A process for preparing N-vinylpyrrolidone by reacting 2-pyrrolidone with acetylene, wherein the 2-pyrrolidone used as a starting material (referred to hereinafter as starting 2-pyrrolidone) comprises less than 1 part by weight of ?-butyrolactone per 100 parts by weight of 2-pyrrolidone.Type: ApplicationFiled: November 26, 2008Publication date: February 10, 2011Applicant: BASF SEInventors: Wolfgang Staffel, Stefan Kaeshammer, Roland Kessinger, Regina Vogelsang, Axel Paul, Lembit Tuttelberg
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Patent number: 6120802Abstract: The present invention relates to a process for producing multilayer, solid drug forms for oral or rectal administration, which comprises coextrusion of at least two compositions which in each case comprise a thermoplastic, pharmacologically acceptable polymeric binder which is soluble or swellable in a physiological environment, and at least one of which contains a pharmaceutical active ingredient, and shaping the coextruded multilayer material to the required drug form.Type: GrantFiled: April 15, 1998Date of Patent: September 19, 2000Assignee: BASF AktiengesellschaftInventors: Jorg Breitenbach, Axel Paul Hartl, Jurgen Hofmann, Joerg Rosenberg, Michael Schiessl, Hans Dieter Zettler
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Patent number: 6037381Abstract: The invention relates to a process for preparing hydroxyl-containing polymers, in particular for preparing polytetrahydrofuran with terminal hydroxyl groups, from the corresponding acyloxy-containing polymers by transesterification with alcohols in the presence of a sodium-containing catalyst. In this process the polytetrahydrofuiran solution is passed in the presence of a catalytic amount of water directly through at least one ion exchanger following the transesterification in order to remove the sodium cations.The novel process makes it possible to remove the sodium cations from the sodium-containing catalyst in an economic manner and with little complexity. The residual sodium content can be reduced to values of less than 0.5 ppm.Type: GrantFiled: December 28, 1998Date of Patent: March 14, 2000Assignee: BASF AktiengesellschaftInventors: Wulfrich Friedemann Beer, Klaus Beiser, Jurgen Ciprian, Lothar Franz, Wolfgang Franzischka, Christof Palm, Frank-Friedrich Pape, Axel Paul, Ulrich-Dieter Pessel, Alexander Weck
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Patent number: 5767329Abstract: Impurities are separated from aqueous solutions of 1,6-hexanediol or 1,6-hexanediol precursors, such as adipic and 6-hydroxycaproic acid, by a process which comprises adding at least one carboxylic acid to a solution (a) of 1,6-hexanediol and subjecting this solution (a) or a solution (b) containing carboxylic acid(s) as precursor(s) of 1,6-hexanediol to a heat treatment at temperatures above room temperature in the absence of hydrogen.Type: GrantFiled: July 1, 1997Date of Patent: June 16, 1998Assignee: BASF AktiengesellschaftInventors: Roman Dostalek, Rolf Fischer, Wolfgang Harder, Axel Paul, Rolf Pinkos
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Patent number: 5756845Abstract: A process for the preparation of 3-aminomethyl-3,5,5-trimethylcyclohexylamine from 3-cyano-3,5,5-trimethylcyclohexanone which requires three spatially separated reaction spaces, in order to carry out the following three steps in sequence:a) reacting the 3-cyano-3,5,5-trimethylcyclohexanone with excess ammonia on acidic metal-oxide catalysts in a first reaction space at from 20.degree. to 150.degree. C. and from 50 to 300 bar,b) hydrogenating the resultant reaction products using hydrogen in a second reaction space in the presence of excess ammonia and preferably liquid ammonia on hydrogenation catalysts, optionally using basic components or on neutral or basic supports at from 50.degree. to 100.degree. C. and at from 50 to 300 bar, andc) hydrogenating the resultant reaction products in the presence of hydrogen and also ammonia in a third reaction space on hydrogenation catalysts, optionally using basic components or on neutral or basic supports at from 110.degree. to 160.degree. C. and at from 150 to 300 bar.Type: GrantFiled: February 28, 1996Date of Patent: May 26, 1998Assignee: BASF AktiengesellschaftInventors: Guido Voit, Tom Witzel, Boris Breitscheidel, Wolfgang Harder, Hermann Luyken, Axel Paul, Karl-Heinz Ross, Peter Wahl
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Patent number: 5455325Abstract: Optically active compounds of the formula I ##STR1## where R is C.sub.1 -C.sub.12 -alkyl or -perfluoroalkyl in which one or two non-adjacent CH.sub.2 or CF.sub.2 groups can also be replaced by --O-- and/or --CO-- and/or --CO--O-- and/or --CH.dbd.CH-- and/or --CH-halogen- and/or --CHCN-- and/or --O--CO--CH-halogen- and/or --O--CO--CHCN--, or is C.sub.1 -C.sub.12 -alkyl which can have a terminal chemically reactive group and in which a CH.sub.2 group can be replaced by --O--,A.sup.1 and A.sup.2 are each, independently of one another, 1,4-phenylene which is unsubstituted or substituted by one or two F and/or Cl and/or Br atoms and/or CH.sub.3 groups and/or CN groups and in which one or two CH groups can also be replaced by N, 1,4-cyclohexylene in which one or two non-adjacent CH.sub.2 groups can also be replaced by --O-- and/or --S--, 1,4-piperidinediyl, 1,4-bicyclo[2.2.2]octylene, 2,6-naphthalenediyl, decahydro-2,6-naphthalenediyl or 1,2,3,4-tetrahydro-2,6-naphthalenediyl,A.sup.Type: GrantFiled: April 22, 1994Date of Patent: October 3, 1995Assignee: BASF AktiengesellschaftInventors: Volker Bach, Wolfgang Brox, Karl-Heinz Etzbach, Axel Paul, Karl Siemensmeyer
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Patent number: 5350873Abstract: Optically active compounds of the formula I ##STR1## where R is C.sub.1 -C.sub.12 -alkyl or -perfluoroalkyl in which one or two non-adjacent CH.sub.2 or CF.sub.2 groups can also be replaced by --O-- and/or --CO-- and/or --CO--O-- and/or --CH.dbd.CH-- and/or --CH-halogen-- and/or --CHCN-- and/or --0--CO--CH-halogen-- and/or --O--CO--CHCN--, or is C.sub.1 -C.sub.12 -alkyl which can have a terminal chemically reactive group and in which a CH.sub.2 group can be replaced by --O--,A.sup.1 and A.sup.2 are each, independently of one another, 1,4-phenylene which is unsubstituted or substituted by one or two F and/or Cl and/or Br atoms and/or CH.sub.3 groups and/or CN groups and in which one or two CH groups can also be replaced by N, 1,4-cyclohexylene in which one or two non-adjacent CH.sub.2 groups can also be replaced by --O-- and/or --S--, 1,4-piperidinediyl, 1,4-bicyclo[2.2.2]octylene, 2,6-naphthalenediyl, decahydro-2,6-naphthalenediyl or 1,2,3,4-tetrahydro-2,6-naphthalenediyl,A.sup.Type: GrantFiled: August 13, 1992Date of Patent: September 27, 1994Assignee: BASF AktiengesellschaftInventors: Volker Bach, Wolfgang Brox, Karl-Heinz Etzbach, Axel Paul, Karl Siemensmeyer
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Patent number: 5212027Abstract: Novel laser-optical recording elements which can be repeatedly erased and recorded on contain recording layers (a) which exhibit enantiotropic, ferroelectric smectic liquid crystalline (S.sub.c*) behavior, so that they can be switched back and forth between two thermodynamically stable, optically distinguishable ferroelectric smectic liquid crystalline S.sub.c* order states on exposure to a laser beam of sufficient luminous power, by applying an external electric field. The recording layers (a) themselves consist mainly or exclusively of novel polymers P having chiral mesogenic side groups.Type: GrantFiled: December 30, 1991Date of Patent: May 18, 1993Assignee: BASF AktiengesellschaftInventors: Karl-Heinz Etzbach, Gerhard Wagenblast, Wolfgang Brox, Axel Paul, Volker Bach
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Patent number: 5208333Abstract: (2R)-1-(Aryloxy)-3-(butyryloxy)-2-propanols of the general formula (I), ##STR1## where Ar is a monocyclic or polycyclic aromatic or heteroaromatic radical, and a process for their preparation by the reaction of (2R)-glycidyl butyrate with an aromatic hydroxy compound Ar--OH in the presence of a quaternary ammonium halide.Type: GrantFiled: December 9, 1988Date of Patent: May 4, 1993Assignee: BASF AktiengesellschaftInventors: Axel Paul, Wolfgang Ladner, Hardo Siegel
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Patent number: 5187248Abstract: Novel laser-optical recording elements which can be repeatedly erased and recorded on contain recording layers (a) which exhibit enantiotropic, ferroelectric smectic liquid crystalline (S.sub.c*) behavior, so that they can be switched back and forth between two thermodynamically stable, optically distinguishable ferroelectric smectic liquid crystalline S.sub.C* order states on exposure to a laser beam of sufficient luminous power, by applying an external electric field. The recording layers (a) themselves consist mainly or exclusively of novel polymers P having chiral mesogenic side groups.Type: GrantFiled: December 30, 1991Date of Patent: February 16, 1993Assignee: BASF AktiengesellschaftInventors: Karl-Heinz Etzbach, Gerhard Wagenblast, Wolfgang Brox, Axel Paul, Volker Bach
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Patent number: 5187298Abstract: Novel laser-optical recording elements which can be repeatedly erased and recorded on contain recording layers (a) which exhibit enantiotropic, ferroelectric smectic liquid crystalline (S.sub.C*) behavior, so that they can be switched back and forth between two thermodynamically stable, optically distinguishable ferroelectric smectic liquid crystlaline S.sub.C* order states on exposure to a laser beam of sufficient luminous power, by applying an external electric field. The recording layers (a) themselves consist mainly or exclusively of novel polymers P having chiral mesogenic side groups.Type: GrantFiled: May 18, 1990Date of Patent: February 16, 1993Assignee: BASF AktiengesellschaftInventors: Kark-Heinz Etzbach, Gerhard Wagenblast, Wolfgang Brox, Axel Paul, Volker Bach
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Patent number: 5102799Abstract: Immobilized lipase is prepared by forming a mixture of hydrophilized polyolefin fibers, crude porcine pancreas lipase, one or more water soluble dihydric to hexahydric aliphatic alcohols of 2 to 6 carbons and an aqueous buffer solution of pH 5-9 at a temperature of 0.degree. to 40.degree. C., allowing the mixture to stand for 1 minute to 3 days, filtering the mixture and washing the resultant filter cake. The dihydric to hexahydric alcohol may be combined with one or more water soluble monohydric alcohols having 1 to 4 carbon atoms. The immobilized lipase is used for resolving racemates of esters of racemic alcohols in an aqueous medium.Type: GrantFiled: November 4, 1988Date of Patent: April 7, 1992Assignee: BASF AktiengesellschaftInventors: Dieter Urban, Wolfgang Ladner, Axel Paul
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Patent number: 5021345Abstract: Lipase is immobilized by mixing a substrate, a crude porcine pancreatic lipase, an aqueous buffer solution at pH 5-9 and one or more water-soluble polyhydric aliphatic alcohols having from 2 to 6 carbon atoms and from 2 to 6 hydroxyl groups at a temperature of from 0.degree. to 40.degree. C. to form a mixture, allowing the mixture to stand for from 1 minute to 3 days, filtering the mixture to produce a filter cake and washing the cake to obtain the immobilized lipase. The substrate is a pulverulent, insoluble, only slightly swellable copolymer of one or more N-vinyllactams of 4 to 6 carbon atoms with a cyclic amide which contains two or more ethylenically unsaturated, copolymerizable groups, one or more of which are bonded directly to amide nitrogen. The polyhydric aliphatic alcohol can be combined with one or more water-soluble monohydric alcohols having from 1 to 4 carbon atoms.Type: GrantFiled: November 4, 1988Date of Patent: June 4, 1991Assignee: BASF AktiengesellschaftInventors: Dieter Urban, Wolfgang Ladner, Axel Paul