Patents by Inventor Axel Scherer

Axel Scherer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Temperature control devices and methods
    Patent number: 9057568
    Abstract: Temperature control devices and methods are described. The described temperature control devices and methods comprise optical emission and detection assemblies and can be used in PCR and qPCR applications.
    Type: Grant
    Filed: December 15, 2009
    Date of Patent: June 16, 2015
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Imran R. Malik, Axel Scherer
  • Surface wave assisted structures and systems
    Patent number: 9041938
    Abstract: A surface wave assisted system having an aperture layer with a surface and an aperture, and a plurality of grooves around the aperture. The plurality of grooves is configured to generate an optical transfer function at the aperture by inducing a surface wave for interfering with transmission of light of a range of spatial frequency.
    Type: Grant
    Filed: January 5, 2012
    Date of Patent: May 26, 2015
    Assignee: California Institute of Technology
    Inventors: Guoan Zheng, Xiquan Cui, Xin Heng, Changhuei Yang, Axel Scherer
  • III-V photonic crystal microlaser bonded on silicon-on-insulator
    Patent number: 9042418
    Abstract: Novel methods and systems for miniaturized lasers are described. A photonic crystal is bonded to a silicon-on-insulator wafer. The photonic crystal includes air-holes and can include a waveguide which couples the laser output to a silicon waveguide.
    Type: Grant
    Filed: December 23, 2013
    Date of Patent: May 26, 2015
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Seheon Kim, William Dos Santos Fegadolli, Axel Scherer
  • Bio-diagnostic testing system and methods
    Patent number: 9037209
    Abstract: An implantable diagnostic device in accordance with the present disclosure includes a probe assembly that can be implemented in a variety of ways. A few example implementations include: a needle inside which is located a bio-sensor chip (the needle being insertable into a human being); a compact package containing the bio-sensor chip (the compact package configured for placement inside a catheter); or a silicon-based bio-sensor package configured for insertion into a vein.
    Type: Grant
    Filed: December 6, 2012
    Date of Patent: May 19, 2015
    Assignees: SANOFI, CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Axel Scherer, Remi Brouard, III, Emil P. Kartalov, Jingqing Huang
  • Methods of modulating microlasers at ultralow power levels, and systems thereof
    Patent number: 9031102
    Abstract: A microlaser system includes an optical source, a microlaser, an actuator switch, and a photovoltaic power source. The microlaser, which includes a control element, is optically pumped by at least a portion of light emitted by the optical source. The actuator switch is configured to be activated by a triggering event. Furthermore, the photovoltaic power source is coupled in a series connection with the actuator switch and the control element, the series connection configured to connect the photovoltaic power source to the control element of the microlaser when the actuator switch is activated by the triggering event.
    Type: Grant
    Filed: February 11, 2013
    Date of Patent: May 12, 2015
    Assignee: California Institute of Technology
    Inventors: Seheon Kim, Axel Scherer, Aditya Rajagopal, Chieh-Feng Chang
  • Chemical sensing and/or measuring devices and methods
    Patent number: 9018684
    Abstract: Methods for fabricating silicon nanowire chemical sensing devices, devices thus obtained, and methods for utilizing devices for sensing and measuring chemical concentration of selected species in a fluid are described. Devices may comprise a metal-oxide-semiconductor field-effect transistor (MOSFET) structure.
    Type: Grant
    Filed: November 22, 2010
    Date of Patent: April 28, 2015
    Assignee: California Institute of Technology
    Inventors: Andrew P. Homyk, Michael D. Henry, Axel Scherer, Sameer Walavalkar
  • Implantable vascular system biosensor with grown capillary beds and uses thereof
    Patent number: 9011330
    Abstract: An implantable biocompatible biosensor is described herein. The biosensor includes a chip layer including a plurality of holes fabricated vertically there through, a power source, one or more sensors on the chip layer and coupled to the power source and a hydrogel matrix including one or more angiogenesis stimulating factors in contact with the chip layer. The stimulating factors stimulate growth of organic material through the plurality of holes when the biosensor is implanted in a subject.
    Type: Grant
    Filed: July 9, 2013
    Date of Patent: April 21, 2015
    Assignee: California Institute of Technology
    Inventors: Akram Sarwat Sadek, Axel Scherer, Muhammad Mujeeb-U-Rahman
  • Methods for quantitative target detection and related devices and systems
    Patent number: 9005987
    Abstract: Described herein are methods for quantitative target detection in a sample through use of microbeads and related devices and systems.
    Type: Grant
    Filed: April 15, 2010
    Date of Patent: April 14, 2015
    Assignees: University of Southern California, California Institute of Technology
    Inventors: Emil P. Kartalov, Axel Scherer, Clive R. Taylor
  • Fabrication of three-dimensional high surface area electrodes
    Patent number: 9006014
    Abstract: A method for fabricating three dimensional high surface electrodes is described. The methods including the steps: designing the pillars; selecting a material for the formation of the pillars; patterning the material; transferring the pattern to form the pillars; insulating the pillars and providing a metal layer for increased conductivity. Alternative methods for fabrication of the electrodes and fabrication of the electrodes using CMOS are also described.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: April 14, 2015
    Assignee: California Institute of Technology
    Inventors: Muhammad Mujeeb-U-Rahman, Axel Scherer
  • Methods for fabricating high aspect ratio probes and deforming high aspect ratio nanopillars and micropillars
    Patent number: 9005548
    Abstract: Methods for fabricating of high aspect ratio probes and deforming micropillars and nanopillars are described. Use of polymers in deforming nanopillars and micropillars is also described.
    Type: Grant
    Filed: February 24, 2010
    Date of Patent: April 14, 2015
    Assignee: California Institute of Technology
    Inventors: Michael D. Henry, Andrew P. Homyk, Axel Scherer, Thomas A. Tombrello, Sameer Walavalkar
  • Microfluidic separation device and method of making same
    Patent number: 8986542
    Abstract: A device and method for making a microfluidic separation device. A microfluidic separation device could include a microfluidic column having an inlet, the microfluidic column being configured to hold a first fluid and the microfluidic column including a porous portion, and an outlet attached to the microfluidic column, the outlet being configured to output a second fluid. The method may include providing a microfluidic column having an inlet, configuring the microfluidic column to hold a first fluid, forming a porous portion in the microfluidic column, and attaching an outlet to the microfluidic column.
    Type: Grant
    Filed: February 8, 2008
    Date of Patent: March 24, 2015
    Assignee: California Institute of Technology
    Inventors: George Maltezos, Alvaro Gomez, Frank Gomez, Axel Scherer
  • Methods for measuring samples using consumer electronic devices and systems
    Patent number: 8980550
    Abstract: Methods for measuring and analyzing biological or chemical samples using consumer electronic devices and systems are described. Moreover, an accessory to enable using devices such as cell phones and smartphones with fluidic illumination chambers are described.
    Type: Grant
    Filed: January 19, 2011
    Date of Patent: March 17, 2015
    Assignee: California Institute of Technology
    Inventors: Imran R. Malik, Axel Scherer
  • Meandering channel fluid device and method
    Patent number: 8975065
    Abstract: Methods and devices of performing reactions for which presence of light is desirable are provided. Biological or chemical materials such as algae are put in a chamber shaped as a meandering fluid channel. The algae can be combined with biomass such as human or animal waste and then subject to light, such as natural light or light coming from a LED, to produce fuel. Production of fuel can be optimized by controlling the height-to-width ratio of the channels.
    Type: Grant
    Filed: July 23, 2007
    Date of Patent: March 10, 2015
    Assignee: California Institute of Technology
    Inventors: George Maltezos, Axel Scherer
  • Methods of fabrication of cartridges for biological analysis
    Patent number: 8968585
    Abstract: Methods to fabricate reaction cartridges for biological sample preparation and analysis are disclosed. A cartridge may have a reaction chamber and openings to allow fluids to enter the chamber. The cartridge may also have handles to facilitate its use. Such cartridges may be used for polymerase chain reaction.
    Type: Grant
    Filed: November 1, 2013
    Date of Patent: March 3, 2015
    Assignee: California Institute of Technology
    Inventors: Imran R. Malik, Axel Scherer, Erika F. Garcia, Xiomara L. Madero
  • SIGNAL ENCODING AND DECODING IN MULTIPLEXED BIOCHEMICAL ASSAYS
    Publication number: 20150057178
    Abstract: This disclosure provides methods, systems, compositions, and kits for the multiplexed detection of a plurality of analytes in a sample. In some examples, this disclosure provides methods, systems, compositions, and kits wherein multiple analytes may be detected in a single sample volume by acquiring a cumulative measurement or measurements of at least one quantifiable component of a signal. In some cases, additional components of a signal, or additional signals (or components thereof) are also quantified. Each signal or component of a signal may be used to construct a coding scheme which can then be used to determine the presence or absence of any analyte.
    Type: Application
    Filed: August 5, 2014
    Publication date: February 26, 2015
    Inventors: Emil Kartalov, Aditya Rajagopal, Axel Scherer
  • FULLY WIRELESS CONTINUOUSLY WEARABLE SENSOR FOR MEASUREMENT OF EYE FLUID
    Publication number: 20150057516
    Abstract: Novel methods and systems for monitoring the health of an eye are disclosed. For example, a resonant circuit may be fabricated on a contact lens and this circuit may be coupled to a second circuit having the same resonant current frequency. A change in a property of the eye fluid contacted by the sensor in the contact lens is communicated to an external device and a remedying action is suggested to the wearer.
    Type: Application
    Filed: August 21, 2014
    Publication date: February 26, 2015
    Inventors: Muhammad MUJEEB-U-RAHMAN, Axel SCHERER
  • METHODS FOR FABRICATING HIGH ASPECT RATIO PROBES AND DEFORMING HIGH ASPECT RATIO NANOPILLARS AND MICROPILLARS
    Publication number: 20150050746
    Abstract: Methods for fabricating of high aspect ratio probes and deforming micropillars and nanopillars are described. Use of polymers in deforming nanopillars and micropillars is also described.
    Type: Application
    Filed: October 29, 2014
    Publication date: February 19, 2015
    Inventors: Michael D. HENRY, Andrew P. HOMYK, Axel SCHERER, Thomas A. TOMBRELLO, Sameer WALAVALKAR
  • SAMPLE PREPARATION DEVICES AND SYSTEMS
    Publication number: 20150024481
    Abstract: Devices and system for preparing samples are described. Such devices can comprise fluidic chambers, reservoirs, and movable structures for controlling the movement of samples. The device can also comprise functional elements for performing specific operations.
    Type: Application
    Filed: September 11, 2014
    Publication date: January 22, 2015
    Inventors: Imran R. MALIK, Axel SCHERER
  • Photonic crystal cavities and related devices and methods
    Patent number: 8929415
    Abstract: Photonic crystal cavities and related devices and methods are described. The described cavities can be used as lasers, photovoltaic sources, and single photon sources. The cavities can be both optically and electrically pumped. A fabrication process of the cavities is also described.
    Type: Grant
    Filed: December 3, 2013
    Date of Patent: January 6, 2015
    Assignee: California Institute of Technology
    Inventors: Seheon Kim, Axel Scherer
  • NANO-PILLAR TRANSISTOR FABRICATION AND USE
    Publication number: 20140357974
    Abstract: A field effect nano-pillar transistor has a pillar shaped gate element incorporating a biomimitec portion that provides various advantages over prior art devices. The small size of the nano-pillar transistor allows for advantageous insertion into cellular membranes, and the biomimitec character of the gate element operates as an advantageous interface for sensing small amplitude voltages such as transmembrane cell potentials. The nano-pillar transistor can be used in various embodiments to stimulate cells, to measure cell response, or to perform a combination of both actions.
    Type: Application
    Filed: August 19, 2014
    Publication date: December 4, 2014
    Inventors: Aditya RAJAGOPAL, Axel SCHERER, Michael D. HENRY, Sameer WALAVALKAR, Thomas A. TOMBRELLO, Andrew P. HOMYK