Patents by Inventor Axel Schroth

Axel Schroth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Purification of pegylated polypeptides
    Patent number: 8889837
    Abstract: The invention is a method for the purification of mono-PEGylated erythropoietin using two cation exchange chromatography steps wherein the same type of cation exchange material is used in both cation exchange chromatography steps and a method for producing a mono-PEGylated erythropoietin in substantially homogeneous form.
    Type: Grant
    Filed: January 24, 2011
    Date of Patent: November 18, 2014
    Assignee: Hoffman-La Roche Inc.
    Inventors: Josef Burg, Klaus Reichert, Axel Schroth, Hartmut Schurig, Axel Wessner
  • Chromatographic methods
    Patent number: 8795533
    Abstract: The current invention comprises a method for the regeneration of a cation exchange chromatography column.
    Type: Grant
    Filed: October 26, 2010
    Date of Patent: August 5, 2014
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Josef Burg, Klaus Reichert, Axel Schroth, Hartmut Schurig, Axel Wessner
  • Purification of pegylated polypeptides
    Patent number: 8138317
    Abstract: The invention is a method for the purification of mono-PEGylated erythropoietin using two cation exchange chromatography steps wherein the same type of cation exchange material is used in both cation exchange chromatography steps and a method for producing a mono-PEGylated erythropoietin in substantially homogeneous form.
    Type: Grant
    Filed: July 16, 2008
    Date of Patent: March 20, 2012
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Josef Burg, Klaus Reichert, Axel Schroth, Hartmut Schurig, Axel Wessner
  • Purification of pegylated polypeptides
    Publication number: 20110118448
    Abstract: The invention is a method for the purification of mono-PEGylated erythropoietin using two cation exchange chromatography steps wherein the same type of cation exchange material is used in both cation exchange chromatography steps and a method for producing a mono-PEGylated erythropoietin in substantially homogeneous form.
    Type: Application
    Filed: January 24, 2011
    Publication date: May 19, 2011
    Inventors: Josef Burg, Klaus Reichert, Axel Schroth, Hartmut Schurig, Axel Wessner
  • Chromatographic methods
    Publication number: 20110065903
    Abstract: The current invention comprises a method for the regeneration of a cation exchange chromatography column.
    Type: Application
    Filed: October 26, 2010
    Publication date: March 17, 2011
    Inventors: Josef Burg, Klaus Reichert, Axel Schroth, Hartmut Schurig, Axel Wessner
  • Chromatographic methods
    Patent number: 7846336
    Abstract: The current invention comprises a method for the regeneration of a cation exchange chromatography column.
    Type: Grant
    Filed: July 16, 2008
    Date of Patent: December 7, 2010
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Josef Burg, Klaus Reichert, Axel Schroth, Hartmut Schurig, Axel Wessner
  • Purification of pegylated polypeptides
    Publication number: 20090118476
    Abstract: The invention is a method for the purification of mono-PEGylated erythropoietin using two cation exchange chromatography steps wherein the same type of cation exchange material is used in both cation exchange chromatography steps and a method for producing a mono-PEGylated erythropoietin in substantially homogeneous form.
    Type: Application
    Filed: July 16, 2008
    Publication date: May 7, 2009
    Inventors: Josef Burg, Klaus Reichert, Axel Schroth, Hartmut Schurig, Axel Wessner
  • Chromatographic methods
    Publication number: 20090101585
    Abstract: The current invention comprises a method for the regeneration of a cation exchange chromatography column.
    Type: Application
    Filed: July 16, 2008
    Publication date: April 23, 2009
    Inventors: Josef Burg, Klaus Reichert, Axel Schroth, Hartmut Schurig, Axel Wessner
  • Method and device for the two-step production of acrylic acid
    Patent number: 7115775
    Abstract: ?,?-ethylenically unsaturated aldehydes and/or carboxylic acids are prepared by means of a two-stage catalytic gas-phase oxidation in which a gas mixture comprising at least an alkane or alkene having from three to six carbon atoms and oxygen is subjected to a catalytic oxidation reaction, in the first stage (1). oxygen is added to the gases produced in the first stage (1) and the resulting mixture is introduced into the second stage (2) in which it is subjected to a further catalytic oxidation reaction. In the process of the present invention, a signal which correlates with the oxygen content of the reaction gases before and/or after the addition of oxygen between the first and second stages (1, 2) is generated and the oxygen addition is regulated as a function of the signal.
    Type: Grant
    Filed: April 8, 2002
    Date of Patent: October 3, 2006
    Assignee: BASF Aktiengesellschaft
    Inventors: Thomas Buschulte, Volker Diehl, Bernd Hagen, Volker Huth, Wolfgang Kasten, Peter Schlemmer, Axel Schroth
  • Method and device for the two-step production of acrylic acid
    Publication number: 20060183940
    Abstract: ?,?-ethylenically unsaturated aldehydes and/or carboxylic acids are prepared by means of a two-stage catalytic gas-phase oxidation in which a gas mixture comprising at least an alkane or alkene having from three to six carbon atoms and oxygen is subjected to a catalytic oxidation reaction, in the first stage (1). Oxygen is added to the gases produced in the first stage (1) and the resulting mixture is introduced into the second stage (2) in which it is subjected to a further catalytic oxidation reaction. In the process of the present invention, a signal which correlates with the oxygen content of the reaction gases before and/or after the addition of oxygen between the first and second stages (1, 2) is generated and the oxygen addition is regulated as a function of the signal.
    Type: Application
    Filed: April 5, 2006
    Publication date: August 17, 2006
    Applicant: BASF Aktiengesellschaft
    Inventors: Thomas Buschulte, Volker Diehl, Bernd Hagen, Volker Huth, Wolfgang Kasten, Peter Schlemmer, Axel Schroth
  • Method and device for the two-step production of acrylic acid
    Publication number: 20040138499
    Abstract: &agr;,&bgr;-ethylenically unsaturated aldehydes and/or carboxylic acids are prepared by means of a two-stage catalytic gas-phase oxidation in which a gas mixture comprising at least an alkane or alkene having from three to six carbon atoms and oxygen is subjected to a catalytic oxidation reaction, in the first stage (1). oxygen is added to the gases produced in the first stage (1) and the resulting mixture is introduced into the second stage (2) in which it is subjected to a further catalytic oxidation reaction. In the process of the present invention, a signal which correlates with the oxygen content of the reaction gases before and/or after the addition of oxygen between the first and second stages (1, 2) is generated and the oxygen addition is regulated as a function of the signal.
    Type: Application
    Filed: October 9, 2003
    Publication date: July 15, 2004
    Inventors: Thomas Buschulte, Volker Diehl, Bernd Hagen, Volker Huth, Wolfgang Kasten, Peter Schlemmer, Axel Schroth