Abstract: Described is a needle assembly system comprising a needle assembly including a needle and a needle support, and a cover including a distal portion adapted to house at least a distal end of the needle and a proximal portion adapted to house the needle support. The proximal portion includes a first portion and a second portion. The first portion has a first inner diameter substantially equal to an outer diameter of the needle support and the second portion has a second inner diameter greater than the diameter of the needle support.

Abstract: Described is a needle assembly removal device comprising an inner portion, a channel formed in the inner portion, and an outer portion movably disposed on the inner portion. The channel has a proximal opening. Movement of the outer portion relative to the inner portion in a first direction causes the inner portion to change the proximal opening from a first width to a second width.

Abstract: The present invention relates to a drug delivery device for administering a dose of a medicament, comprising of a first housing component; a second housing component releasably interconnectable with the first housing component in a locked configuration, in which the second housing component covers a dispensing end of the device; and a safety lock member to mechanically engage with the first and with the second housing component in order to inhibit unintentional release of first and second housing component.

Abstract: The present invention relates to a service and maintenance station for a handheld drug delivery device of pen-injector type, comprising: a receptacle section to receive at least a portion of the drug delivery device, at least one service module adapted to maintain and/or to restore the operability of the drug delivery device, wherein the at least one service module comprises a cleaning and/or sterilizing module adapted to receive, to clean and/or to sterilize a distal end section of the drug delivery device to be connected with a piercing assembly.

Abstract: The present invention relates to a drug delivery for dispensing of a dose of a medicament comprising: a housing, adapted to receive a drive mechanism, a cartridge holder to receive a cartridge comprising a medicament, and a protective cap adapted to at least partially enclose a distal end section of the cartridge holder and being pivot mounted on the housing or on the cartridge holder.

Abstract: A cartridge holder suitable for an injection device is proposed. The injection device is adapted to administer a dose of a medicament to a patient. The cartridge holder is adapted to receive a medical cartridge containing the dose of the medicament. The cartridge holder comprises an annular collar with a first set (S1) of first detents arranged around a circumference of the annular collar. Each first detent projects from an inner surface of the annular collar in a radial inward direction. The first detent is adapted to engage a corresponding second detent of the medical cartridge to mount the medical cartridge to the cartridge holder. The first detent is resiliently arranged and/or supported so as to provide a unidirectional torque limiter that restricts a maximal torque between the cartridge holder and the medical cartridge in a first rotational direction (R1).

Abstract: The present invention relates A needle assembly for a drug delivery device comprising: a cup-shaped receptacle of non-circular cross section having a bottom section supporting a needle element being adapted to penetrate a pierceable seal of a cartridge to be disposed in a cartridge holder of the drug delivery device, wherein the receptacle comprises fastening means adapted to engage with fastening means of a support section of the cartridge holder for releasably fastening the needle assembly, wherein the fastening means are convertible into a release configuration by changing the radial distance of mutually corresponding fastening means through twisting the receptacle with respect to the support section.

Abstract: The present invention relates to a drug delivery device for injecting a dose of a medicament, comprising of a cartridge holder adapted to house a cartridge filled with the medicament and comprising a displaceable piston, a body adapted to house a drive mechanism comprising a piston rod to be operably engaged with the piston of the cartridge for expelling a dose of the medicament, wherein the cartridge holder and the body are interconnected with each other and wherein the cartridge holder and/or the body comprise at least one separate fractionizing piece irreversibly detachable from the cartridge holder and/or from the body to irreversibly abrogate the interconnection of cartridge holder and body.

Abstract: Disclosed herein are various examples of a drug delivery system having a non-detachable reservoir holder. The drug delivery system includes a dose setting mechanism and a reservoir holder attached to the dose setting mechanism, wherein the reservoir holder is configured to partially detach from the dose setting mechanism to allow for (i) insertion of a reservoir into the reservoir holder without being fully detached from the dose setting mechanism and (ii) removal of the reservoir from the reservoir holder without being fully detached from the dose setting mechanism.

Abstract: The present invention relates to a drug delivery device for injecting a dose of a medicament, comprising of a cartridge holder adapted to house a cartridge filled with the medicament and comprising a displaceable piston, and at least a body adapted to house a drive mechanism comprising a piston rod to be operably engaged with the piston of the cartridge for expelling a dose of the medicament, wherein the cartridge holder and the body are interconnected with each other and wherein the cartridge holder and/or the body comprise at least one fractionizing means adapted to irreversibly abrogate the interconnection of cartridge holder and body.

Abstract: The present invention relates to a drug delivery device for injecting a dose of a medicament, comprising: at least one housing component adapted to house a cartridge containing the medicament and a drive mechanism operably engaged with the cartridge for expelling a dose of the medicament, wherein the housing component comprises at least one disaggregating means for at least partially dividing the housing component into at least two pieces for gaining access to the cartridge disposed therein.

Abstract: The present invention relates to an assembly device for assembling and/or disassembling at least one needle unit and a drug delivery device, wherein the assembly device comprises: a deposition means adapted to bring or to keep the drug delivery device in an assembly position, a holder for at least one needle unit, and an assembly unit adapted to assemble and/or to disassemble the needle unit and the drug delivery device.

Abstract: The present invention relates to a needle assembly for a drug delivery device comprising of a cup-shaped receptacle having a bottom section supporting a needle element being adapted to penetrate a pierceable seal of a cartridge to be disposed in a cartridge holder of the drug delivery device, wherein the receptacle comprises fastening means for releasably fastening the needle assembly to the cartridge holder, and wherein the fastening means is convertible into a release configuration by way of an elastic deformation of the receptacle.

Abstract: The present invention relates to a drive mechanism for a drug delivery device, comprising a number of mechanically interacting functional components among which at least a piston rod is adapted to transfer thrust to a piston of a cartridge that contains a medicinal product to be dispensed, wherein at least one of the functional components at least in sections comprises a friction-reducing slide coating. In this way, a force level required for dispensing and/or setting of a dose can be effectively reduced.

Abstract: The present invention relates to a cartridge holder for a drug delivery device and to a corresponding drug delivery device, wherein the cartridge holder comprises: a proximal portion (36) for receiving a cartridge (12) filled with a medicinal fluid to be dispensed by the drug delivery device, a distal portion (34) comprising a mount for a piercing assembly (24, 25, 30), wherein the piercing assembly is adapted to provide a fluid-transferring connection with the inner volume of the cartridge (12) by way of a piercing element (30) pointing in distal direction with a pointed free end section; and retaining means (40; 42; 44) adapted to substantially prevent the cartridge (12) from displacing in proximal direction with respect to the proximal portion (36) and/or distal portion (34).

Abstract: The present invention relates to a cartridge holder assembly for a drug delivery device as well as to such drug delivery device and to a corresponding method of assembly, wherein the cartridge holder assembly comprises: a cartridge holder (14; 40) adapted to receive a cartridge (12) to be filled with a medicinal product to be dispensed by the drug delivery device, wherein the cartridge holder (14; 40) comprises at least one through opening at a distal end section to receive a piercing element (20) being adapted to penetrate a sealing septum (22) of the cartridge (12), a constriction member (26; 42) being adapted to axially abut against the septum (22) and comprising a through opening (34; 52) to receive the piercing element (20), wherein said through opening (34; 52) is adjustable in diameter.

Abstract: The present invention relates to an arrangement for use in a drug delivery device comprising a cartridge holder, the cartridge holder comprising an opening at its distal end, a needle holder and one or more intermediate elements, wherein when the needle holder is mounted to the cartridge holder and the one or more intermediate elements are arranged in the opening of the cartridge holder whereby the size of the free space within the opening is reduced. Furthermore, it relates to a drug delivery device which is comprising such an arrangement and to a method for stabilizing a septum located at the distal end of a medicament cartridge.

Abstract: The present invention relates to a drug delivery device for dispensing of a dose of a medicinal product, comprising, a housing, a drive mechanism comprising an axially displaceable piston rod to act on a piston of a cartridge containing the medicinal product to be dispensed, wherein the housing is adapted to support a piercing element which is adapted to penetrate a distal end face of the cartridge exclusively on demand. Furthermore, the drug delivery device comprises means for displacing the cartridge from a proximal stop position to a distal stop position in an axial direction and with respect to the housing, wherein in the distal stop position, the cartridge is connected to the piercing element and wherein in the proximal stop position, the cartridge is disconnected from the piercing element such that a fluid transfer between inside volume of the cartridge and the piercing element is interrupted.

Abstract: The present invention relates to a drive mechanism for a drug delivery device, comprising: a housing, an axially displaceable piston rod to act on a piston of a cartridge containing a medicinal product to be dispensed, a drive member threadedly engaged with the piston rod and being slidably disposed relative to the housing between a distal stop position and a proximal stop position, wherein for setting of a dose, the drive member is rotatable with respect to the housing (14), a dose dial member operably engaged with the drive member by means of a reduction gear, wherein the drive member at its proximal end section comprises a radially extending receptacle adapted to receive the reduction gear.

Abstract: A drive mechanism for a drug delivery device, preferably for a pen-type injector, the mechanism comprises a spindle (6) movable in a first direction during a delivery step, a splined portion (5, 11) operatively coupled to the spindle (6), and retraction means (12, 15, 16, 17, 20) acting on the splined portion (5, 11) at least at the end of the delivery step. Thereby, that after the delivery step the spindle (6) and/or the splined portion (5, 11) is moved in a second direction contrary to the first direction, such that the whole drive mechanism is relieved from stresses.