Patents by Inventor Axel Thomas Lehrer

Axel Thomas Lehrer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant proteins from filoviruses and their use
    Publication number: 20120065371
    Abstract: Filovirus subunit protein immunogens are produced using a recombinant expression system and combined with one or more adjuvants in immunogenic formulations. The subunit proteins include GP95, GP-FL, VP40, VP24, and NP derived from Ebola Virus and Marburg Virus. Adjuvants include saponins, emulsions, alum, and dipeptidyl peptidase inhibitors. The disclosed immunogenic formulations are effective in inducing strong antibody responses directed against individual Filovirus proteins and intact Filovirus particles as well as stimulating cell-mediated immune responses to the Filoviruses.
    Type: Application
    Filed: April 4, 2011
    Publication date: March 15, 2012
    Applicant: PanThera Biopharma LLC
    Inventors: Axel Thomas Lehrer, David E. Clements, Tom Humphreys
  • Drosophila cell lines producing recombinant secretable filovirus surface glycoproteins lacking the membrane spanning domain
    Patent number: 7947286
    Abstract: Filovirus subunit protein immunogens are produced using a recombinant expression system and combined with one or more adjuvants in immunogenic formulations. The subunit proteins include GP95, GP-FL, VP40, VP24, and NP derived from Ebola Virus and Marburg Virus. Adjuvants include saponins, emulsions, alum, and dipeptidyl peptidase inhibitors. The disclosed immunogenic formulations are effective in inducing strong antibody responses directed against individual Filovirus proteins and intact Filovirus particles as well as stimulating cell-mediated immune responses to the Filoviruses.
    Type: Grant
    Filed: October 5, 2006
    Date of Patent: May 24, 2011
    Assignee: PanThera Biopharma LLC
    Inventors: Axel Thomas Lehrer, David Edward Clements, Tom Humphreys