Patents by Inventor Axel Vater

Axel Vater has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for Synthesizing Nucleic Acids, and Application Thereof
    Publication number: 20110027794
    Abstract: The invention relates to a method for synthesizing a nucleic acid containing modified nucleotides. The method encompasses the following steps: a matrix strand is provided; —a primer which at least partially hybridizes on the matrix strand is provided; —nucleoside triphosphates, at least some of which are modified nucleoside triphosphates, are provided; —a polymerase activity is supplied; and—the matrix strand, the primer, and the nucleoside triphosphates are incubated so as to synthesize a nucleic acid that is substantially complementary to the matrix strand. The polymerase activity can be a reverse transcriptase activity.
    Type: Application
    Filed: October 15, 2010
    Publication date: February 3, 2011
    Applicant: NOXXON PHARMA AG
    Inventors: Sven Klussmann, Florian Jarosch, Axel Vater
  • CGRP binding nucleic acids
    Patent number: 7879991
    Abstract: The invention relates to an antagonist for CGRP and amylin, whereby the antagonist is a nucleic acid and said nucleic acid binds to CGRP or amylin. Said nucleic acid preferably comprises an L-nucleotide.
    Type: Grant
    Filed: May 6, 2003
    Date of Patent: February 1, 2011
    Assignee: NOXXON Pharma AG
    Inventors: Axel Vater, Christian Maasch, Florian Jarosch, Mathias Bell, Steffen Helmling, Bernd Eschgfäller, Elisabeth Moyroud, Sandra Stark, Sven Klussmann, Thorsten Ruppert, Gregor Bahrenberg, Clemens Gillen, Klaus Schiene
  • Optical imaging of rheumatoid arthritis
    Patent number: 7879314
    Abstract: The present invention concerns the use of indocarbocyanine dyes, in particular indotricarbocyanine dyes for the diagnosis of inflammatory diseases, in particular rheumatoid arthritis, methods of diagnosing inflammatory diseases and an apparatus useful to carry out the method of diagnosing.
    Type: Grant
    Filed: June 28, 2006
    Date of Patent: February 1, 2011
    Assignee: Bayer Schering Pharma AG
    Inventors: Kai Licha, Michael Schirner, Axel Vater, Sonja Vollmer
  • NOVEL USE OF SPIEGELMERS
    Publication number: 20090192100
    Abstract: The present invention relates to the use of a L-nucleic acid as intracellularly active agent.
    Type: Application
    Filed: May 4, 2006
    Publication date: July 30, 2009
    Inventors: Axel Vater, Christian Maasch, Sven Klussmann, Werner Purschke, Dirk Eulberg, Florian Jarosch, Klaus Buchner
  • Vasopressin-Binding L-Nucleic Acid
    Publication number: 20090181909
    Abstract: The invention relates to a vasopressin-binding nucleic acid, characterized in that the nucleic acid has a Box 1 segment The and a Box 2 segment, Box 1 having the sequence GAGS, in which W=A or U, preferably W=U, and Box 2 having a sequence comprised of approximately 18 to 24 nucleotides, preferably 21 nucleotides, and a group (G)n being contained four times in the sequence, whereby n=2, 3 or 4.
    Type: Application
    Filed: November 29, 2005
    Publication date: July 16, 2009
    Applicant: Noxxon Pharma AG
    Inventors: Werner Purschke, Dirk Eulberg, Sven Klussmann, Ingo Rohl, Axel Vater
  • Method for the Synthesizing Nucleic Acids, and Application Thereof
    Publication number: 20080070238
    Abstract: The invention relates to a method for synthesizing a nucleic acid comprising modified nucleotides. Said method encompasses the following steps: a matrix strand is provided; —a primer which at least partially hybridizes on the matrix strand is provided; —nucleoside triphosphates, at least some of which are modified nucleoside triphosphates, are provided; —a polymerase activity is supplied; and —the matrix strand, the primer, and the nucleoside triphosphates are incubated so as to synthesize a nucleic acid that is substantially complementary to the matrix strand. The inventive method is characterized in that the polymerase activity represents a reverse transcriptase activity.
    Type: Application
    Filed: September 14, 2004
    Publication date: March 20, 2008
    Inventors: Sven Klussmann, Florian Jarosch, Axel Vater
  • Optical imaging of rheumatoid arthritis
    Publication number: 20070059244
    Abstract: The present invention concerns the use of indocarbocyanine dyes, in particular indotricarbocyanine dyes for the diagnosis of inflammatory diseases, in particular rheumatoid arthritis, methods of diagnosing inflammatory diseases and an apparatus useful to carry out the method of diagnosing.
    Type: Application
    Filed: June 28, 2006
    Publication date: March 15, 2007
    Inventors: Kai Licha, Michael Schirner, Axel Vater, Sonja Vollmer
  • Cgrp binding nucleic acids
    Publication number: 20060183700
    Abstract: The invention relates to an antagonist for CGRP and amylin, whereby the antagonist is a nucleic acid and said nucleic acid binds to CGRP or amylin. Said nucleic acid preferably comprises an L-nucleotide.
    Type: Application
    Filed: May 6, 2003
    Publication date: August 17, 2006
    Applicant: NOXXON Pharma AG
    Inventors: Axel Vater, Christian Maasch, Florian Jarosch, Mathias Bell, Steffen Helmling, Bernd Eschgfaller, Elisabeth Moyroud, Sandra Stark, Sven Klussmann, Thorsten Ruppert, Gregor Bahrenberg, Clemens Gillen, Klaus Schiene