Patents by Inventor Ayako Horigome

Ayako Horigome has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230066928
    Abstract: Novel Bifidobacterium bacteria having an opioid peptide decomposition action and a noncollagenous glycoprotein decomposition action are provided. The present invention relates to one or more kinds of Bifidobacterium bacteria selected from the group consisting of Bifidobacterium bifidum MCC1092 (NITE BP-02429), Bifidobacterium bifidum MCC1319 (NITE BP-02431), Bifidobacterium bifidum MCC1868 (NITE BP-02432), Bifidobacterium bifidum MCC1870 (NITE BP-02433), and Bifidobacterium longum subsp. longum MCC1110 (NITE BP-02430), as well as a composition for decomposing an opioid peptide and composition for decomposing a noncollagenous glycoprotein containing the Bifidobacterium bacteria as an active ingredient.
    Type: Application
    Filed: October 18, 2022
    Publication date: March 2, 2023
    Applicant: MORINAGA MILK INDUSTRY CO., LTD.
    Inventors: Takuma Sakurai, Nanami Hashikura, Kanetada Shimizu, Sachiko Takahashi, Ayako Horigome
  • Patent number: 11504407
    Abstract: Novel Bifidobacterium bacteria having an opioid peptide decomposition action and a noncollagenous glycoprotein decomposition action are provided. The present invention relates to one or more kinds of Bifidobacterium bacteria selected from the group consisting of Bifidobacterium bifidum MCC1092 (NITE BP-02429), Bifidobacterium bifidum MCC1319 (NITE BP-02431), Bifidobacterium bifidum MCC1868 (NITE BP-02432), Bifidobacterium bifidum MCC1870 (NITE BP-02433), and Bifidobacterium longum subsp. longum MCC1110 (NITE BP-02430), as well as a composition for decomposing an opioid peptide and composition for decomposing a noncollagenous glycoprotein containing the Bifidobacterium bacteria as an active ingredient.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: November 22, 2022
    Assignee: MORINAGA MILK INDUSTRY CO., LTD.
    Inventors: Takuma Sakurai, Nanami Hashikura, Kanetada Shimizu, Sachiko Takahashi, Ayako Horigome
  • Publication number: 20210100852
    Abstract: Novel Bifidobacterium bacteria having an opioid peptide decomposition action and a noncollagenous glycoprotein decomposition action are provided. The present invention relates to one or more kinds of Bifidobacterium bacteria selected from the group consisting of Bifidobacterium bifidum MCC1092 (NITE BP-02429), Bifidobacterium bifidum MCC1319 (NITE BP-02431), Bifidobacterium bifidum MCC1868 (NITE BP-02432), Bifidobacterium bifidum MCC1870 (NITE BP-02433), and Bifidobacterium longum subsp. longum MCC1110 (NITE BP-02430), as well as a composition for decomposing an opioid peptide and composition for decomposing a noncollagenous glycoprotein containing the Bifidobacterium bacteria as an active ingredient.
    Type: Application
    Filed: March 23, 2018
    Publication date: April 8, 2021
    Applicant: MORINAGA MILK INDUSTRY CO., LTD.
    Inventors: Takuma Sakurai, Nanami Hashikura, Kanetada Shimizu, Sachiko Takahashi, Ayako Horigome
  • Patent number: 9014990
    Abstract: By accurately estimating the survival cell count in a probiotic product, the time for developing the product can be shortened. In a device (1) for estimating survival cell count, a calculation unit (14) calculates an estimated result of the survival cell count nt (CFU/g) of a specific strain contained in a composition after storage, in accordance with the following equation (I). (I) Log10nt=Log10n0?t×EXP{(AT×T+BT)w+(CT×T+DT)}, provided that t stands for the storage period (days)× 1/30, nt stands for the survival cell count (CFU/g) of the strain contained in the composition after the storage period t (days), n0 stands for the viable cell count (CFU/g) of the strain contained in the composition at the initiation of storage, T stands for the storage temperature (° C.), w stands for the water activity value of the composition, AT and CT stand for experimentally determined coefficients specific to the strain, and BT and DT stand for experimentally determined constants specific to the strain.
    Type: Grant
    Filed: May 29, 2009
    Date of Patent: April 21, 2015
    Assignee: Morinaga Milk Industry Co., Ltd.
    Inventors: Fumiaki Abe, Ayako Uchijima, Masamichi Muto, Ayako Horigome
  • Patent number: 8700373
    Abstract: The present invention provides a method for estimating survival cell count, which is able to calculate an accurately estimated result of the survival cell count of a specific strain in a probiotic product with respect to its storage period, and to shorten the time for developing the product, and a method for setting a guaranteed cell count, which is able to readily calculate a guaranteed cell count of a specific strain in a probiotic product within its quality guarantee period. The method for estimating the survival cell count is characterized by estimating the survival cell count nt (CFU/g) of a specific strain contained in a composition after storage, in accordance with the following equation (I).
    Type: Grant
    Filed: May 29, 2009
    Date of Patent: April 15, 2014
    Assignee: Morinaga Milk Industry Co., Ltd.
    Inventors: Fumiaki Abe, Ayako Uchijima, Ayako Horigome
  • Patent number: 8420128
    Abstract: An agent for thermally stabilizing lactoferrin, which comprises a nucleic acid as an active ingredient, can be added to lactoferrin to impart thermal stability to lactoferrin. Thermally stabilized lactoferrin can be heat-sterilized at a pH value around a neutral pH value while keeping its activity.
    Type: Grant
    Filed: March 31, 2009
    Date of Patent: April 16, 2013
    Assignee: Morinaga Milk Industry Co., Ltd.
    Inventors: Ayako Horigome, Mai Murata, Koji Yamauchi, Mitsunori Takase, Yasuhiro Takeda, Junichi Hashimoto, Ikumi Kojima
  • Publication number: 20120177624
    Abstract: Disclosed is a disinfectant which is safe, has few adverse side-effects, can be ingested together with a food or beverage by adding the disinfectant to the food or beverage, shows a bactericidal effect in the oral cavity, and has no problem even when ingested on a daily basis over a long period. Also disclosed is a food additive comprising the disinfectant. Specifically, disclosed is an oral disinfectant for the disinfection of an oral bacterium, which comprises lactoperoxidase, glucose oxidase, glucose and a pH-adjusting component.
    Type: Application
    Filed: March 22, 2012
    Publication date: July 12, 2012
    Applicant: MORINAGA MILK INDUSTRY CO., LTD.
    Inventors: Kouichirou Shin, Ayako Horigome, Koji Yamauchi
  • Publication number: 20110112813
    Abstract: The present invention provides a method for estimating survival cell count, which is able to calculate an accurately estimated result of the survival cell count of a specific strain in a probiotic product with respect to its storage period, and to shorten the time for developing the product, and a method for setting a guaranteed cell count, which is able to readily calculate a guaranteed cell count of a specific strain in a probiotic product within its quality guarantee period. The method for estimating the survival cell count is characterized by estimating the survival cell count nt (CFU/g) of a specific strain contained in a composition after storage, in accordance with the following equation (I).
    Type: Application
    Filed: May 29, 2009
    Publication date: May 12, 2011
    Applicant: MORINAGA MILK INDUSTRY CO., LTD.
    Inventors: Fumiaki Abe, Ayako Uchijima, Ayako Horigome
  • Publication number: 20110071768
    Abstract: By accurately estimating the survival cell count in a probiotic product, the time for developing the product can be shortened. In a device (1) for estimating survival cell count, a calculation unit (14) calculates an estimated result of the survival cell count nt (CFU/g) of a specific strain contained in a composition after storage, in accordance with the following equation (I). (I) Log10 nt=Log10 n0?t×EXP{(AT×T+BT)w+(CT×T+DT)}, provided that t stands for the storage period (days)× 1/30, nt stands for the survival cell count (CFU/g) of the strain contained in the composition after the storage period t (days), n0 stands for the viable cell count (CFU/g) of the strain contained in the composition at the initiation of storage, T stands for the storage temperature (° C.), w stands for the water activity value of the composition, AT and CT stand for experimentally determined coefficients specific to the strain, and BT and DT stand for experimentally determined constants specific to the strain.
    Type: Application
    Filed: May 29, 2009
    Publication date: March 24, 2011
    Applicant: MORINAGA MILK INDUSTRY CO., LTD.
    Inventors: Fumiaki Abe, Ayako Uchijima, Masamichi Muto, Ayako Horigome
  • Publication number: 20100310673
    Abstract: An agent for thermally stabilizing lactoferrin, which comprises a nucleic acid as an active ingredient, can be added to lactoferrin to impart thermal stability to lactoferrin. Thermally stabilized lactoferrin can be heat-sterilized at a pH value around a neutral pH value while keeping its activity.
    Type: Application
    Filed: March 31, 2009
    Publication date: December 9, 2010
    Applicant: MORINAGA MILK INDUSTRY CO., LTD.
    Inventors: Ayako Horigome, Mai Murata, Koji Yamauchi, Mitsunori Takase, Yasuhiro Takeda, Junichi Hashimoto, Ikumi Kojima
  • Publication number: 20100028274
    Abstract: Disclosed is a disinfectant which is safe, has few adverse side-effects, can be ingested together with a food or beverage by adding the disinfectant to the food or beverage, shows a bactericidal effect in the oral cavity, and has no problem even when ingested on a daily basis over a long period. Also disclosed is a food additive comprising the disinfectant. Specifically, disclosed is an oral disinfectant for the disinfection of an oral bacterium, which comprises lactoperoxidase, glucose oxidase, glucose and a pH-adjusting component.
    Type: Application
    Filed: June 28, 2007
    Publication date: February 4, 2010
    Applicant: MORINAGA MILK INDUSTRY CO., LTD.
    Inventors: Kouichirou Shin, Ayako Horigome, Koji Yamauchi