Patents by Inventor Ayako Kamimura
Ayako Kamimura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230263761Abstract: An agent for elevating nitric oxide (NO) concentration comprising glutathione or a salt thereof as an active ingredient; an agent for elevating NO concentration comprising glutathione or a salt thereof as an active ingredient for preventing or ameliorating a vascular endothelial malfunction-related symptom, or dilating blood vessels or promoting blood flow by elevating NO concentration; and a method for elevating NO concentration by ingesting glutathione or a salt thereof.Type: ApplicationFiled: April 11, 2023Publication date: August 24, 2023Applicant: KYOWA HAKKO BIO CO., LTD.Inventors: Masahiko MORITA, Ayako KAMIMURA
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Patent number: 11654125Abstract: An agent for elevating nitric oxide (NO) concentration comprising glutathione or a salt thereof as an active ingredient; an agent for elevating NO concentration comprising glutathione or a salt thereof as an active ingredient for preventing or ameliorating a vascular endothelial malfunction-related symptom, or dilating blood vessels or promoting blood flow by elevating NO concentration; and a method for elevating NO concentration by ingesting glutathione or a salt thereof.Type: GrantFiled: January 21, 2014Date of Patent: May 23, 2023Assignee: KYOWA HAKKO BIO CO., LTD.Inventors: Masahiko Morita, Ayako Kamimura
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Publication number: 20200108034Abstract: The invention provides citrulline or a salt thereof and glutathione or a salt thereof for use in increasing a ratio of muscle mass to total body weight in a person in conjunction with a resistance workout program, as well as a method of increasing a ratio of muscle mass to total body weight in a person by administering citrulline or a salt thereof and glutathione or a salt thereof to the person in conjunction with a resistance workout program. The citrulline and glutathione or salts thereof are administered daily for a period greater than 7 days, whereas the resistance workout program is administered for at least the entire period during which the two compounds are administered. The muscle mass is measured by a body composition meter.Type: ApplicationFiled: May 31, 2018Publication date: April 9, 2020Applicant: KYOWA HAKKO BIO CO., LTD.Inventors: Masahiko MORITA, Ayako KAMIMURA, Darryn S. WILLOUGHBY
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Patent number: 10369185Abstract: A composition for enhancement of ability to concentrate and method of improving ability to concentrate using alanylglutamine or a salt of alanylglutamine as an active ingredient.Type: GrantFiled: May 22, 2015Date of Patent: August 6, 2019Assignee: Kyowa Hakko Bio Co., Ltd.Inventors: Yukihiro Hishida, Takeshi Ikeda, Ryusuke Nakagiri, Ayako Kamimura
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Publication number: 20170189467Abstract: A composition for enhancement of ability to concentrate and method of improving ability to concentrate using alanylglutamine or a salt of alanylglutamine as an active ingredient.Type: ApplicationFiled: May 22, 2015Publication date: July 6, 2017Inventors: Yukihiro Hishida, Takeshi Ikeda, Ryusuke Nakagiri, Ayako Kamimura
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Patent number: 9492494Abstract: An object of the present invention is to provide an oral composition useful for promoting collagen synthesis and the like. The present invention can provide an oral composition containing collagen or gelatin or a degradation product thereof, and hydroxyproline or a salt thereof. The weight ratio of alanine and hydroxyproline contained in the amino acids obtained by hydrolyzing the oral composition is preferably 1:1.5-150.Type: GrantFiled: May 30, 2008Date of Patent: November 15, 2016Assignee: Kyowa Hakko Bio Co., Ltd.Inventors: Ayako Kamimura, Yasushi Sakai, Takeshi Ikeda
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Patent number: 9480668Abstract: The present invention provides a blood flow promoting agent containing citrulline or a salt thereof and capsaicin or capsaicinoids as active ingredients, which is safe even by long-term administration, a food with health claims and a functional food affording such action, particularly, a blood flow promoting agent exhibiting an effective vasodilatory action of capsaicin at a low dose free of irritant property, which can be applied to improvement of athletic performance exhibited in relation to peripheral vasodilatation, suppression of fat accumulation, improvement of skin quality, as well as securing blood circulation in ischemic disease and the like, relaxation of blood vessel biased to coarctation due to advancing age, lifestyle-related diseases and the like, prophylaxis of arteriosclerosis, and prophylaxis of stiff neck, feeling of cold, erectile dysfunction, thrombosis and the like due to blood flow disorder.Type: GrantFiled: November 5, 2013Date of Patent: November 1, 2016Assignee: Kyowa Hakko Bio Co., Ltd.Inventors: Masahiko Morita, Ayako Kamimura, Yoshinori Kobayashi
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Patent number: 9433605Abstract: An object of the present invention is to provide an oral preparation for promoting synthesis of tissue collagen, an oral preparation for promoting healing of skin wounds or an oral preparation for preventing or improving skin wrinkles or sagging, which is safe and has an excellent effect. The present invention can provide an oral preparation for promoting synthesis of tissue collagen, an oral preparation for promoting healing of skin wounds or an oral preparation for preventing or improving skin wrinkles or sagging, which comprises hydroxyproline or a salt thereof as an active ingredient.Type: GrantFiled: April 4, 2013Date of Patent: September 6, 2016Assignee: KYOWA HAKKO BIO CO., LTD.Inventors: Toshikazu Kamiya, Ayako Kamimura, Yoko Kawada
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Patent number: 9375479Abstract: The invention provides an easy-to-drink beverage that contains citrulline, wherein the generation of bad odors due to storage or heating is suppressed. In particular, the invention provides a beverage that contains citrulline, citric acid, sodium citrate, water, and one or more supplements that are saccharides, souring agents, preservatives, colorants, flavoring agents, functional ingredients, or carbon dioxide.Type: GrantFiled: February 7, 2014Date of Patent: June 28, 2016Assignee: Kyowa Hakko Bio Co., Ltd.Inventors: Yasushi Sakai, Takeshi Ikeda, Ayako Kamimura
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Publication number: 20150352067Abstract: An agent for elevating nitric oxide (NO) concentration comprising glutathione or a salt thereof as an active ingredient; an agent for elevating NO concentration comprising glutathione or a salt thereof as an active ingredient for preventing or ameliorating a vascular endothelial malfunction-related symptom, or dilating blood vessels or promoting blood flow by elevating NO concentration; and a method for elevating NO concentration by ingesting glutathione or a salt thereof.Type: ApplicationFiled: January 21, 2014Publication date: December 10, 2015Inventors: Masahiko MORITA, Ayako KAMIMURA
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Publication number: 20150297546Abstract: The present invention provides a blood flow promoting agent containing citrulline or a salt thereof and capsaicin or capsaicinoids as active ingredients, which is safe even by long-term administration, a food with health claims and a functional food affording such action, particularly, a blood flow promoting agent exhibiting an effective vasodilatory action of capsaicin at a low dose free of irritant property, which can be applied to improvement of athletic performance exhibited in relation to peripheral vasodilatation, suppression of fat accumulation, improvement of skin quality, as well as securing blood circulation in ischemic disease and the like, relaxation of blood vessel biased to coarctation due to advancing age, lifestyle-related diseases and the like, prophylaxis of arteriosclerosis, and prophylaxis of stiff neck, feeling of cold, erectile dysfunction, thrombosis and the like due to blood flow disorder.Type: ApplicationFiled: November 5, 2013Publication date: October 22, 2015Inventors: Masahiko MORITA, Ayako KAMIMURA, Yoshinori KOBAYASHI
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Publication number: 20140179783Abstract: The invention provides an easy-to-drink beverage that contains citrulline, wherein the generation of bad odors due to storage or heating is suppressed. In particular, the invention provides a beverage that contains citrulline, citric acid, sodium citrate, water, and one or more supplements that are saccharides, souring agents, preservatives, colorants, flavoring agents, functional ingredients, or carbon dioxide.Type: ApplicationFiled: February 7, 2014Publication date: June 26, 2014Applicant: Kyowa Hakko Bio Co., Ltd.Inventors: Yasushi SAKAI, Takeshi IKEDA, Ayako KAMIMURA
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Patent number: 8679568Abstract: The invention provides an easy-to-drink beverage that contains citrulline, wherein the generation of bad odors due to storage or heating is suppressed. In particular, the invention provides a beverage that contains citrulline and citric acid, as well as sodium citrate or disodium hydrogen phosphate.Type: GrantFiled: November 17, 2008Date of Patent: March 25, 2014Assignee: Kyowa Hakko Bio Co., Ltd.Inventors: Yasushi Sakai, Takeshi Ikeda, Ayako Kamimura
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Patent number: 8575190Abstract: The present invention provides a method for preventing or ameliorating skin psoriasis by applying as an active ingredient, a compound represented by general formula (I) or a salt thereof: (wherein R1, R2, and R3 simultaneously or separately represent a lower alkyl, lower alkenyl, lower alkynyl, aralkyl, araryl, or phenyl group, or a hydrogen atom).Type: GrantFiled: November 12, 2008Date of Patent: November 5, 2013Assignee: Mitsubishi Gas Chemical Company, Inc.Inventors: Ayako Kamimura, Toshikazu Kamiya, Masahiko Nakano, Kazutoshi Kikkawa
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Publication number: 20100261749Abstract: It is an object of the present invention to provide a safe and highly effective preventing or ameliorating agent for skin psoriasis. The present invention provides a preventing or ameliorating agent for skin psoriasis, containing, as an active ingredient, a compound represented by general formula (I) or a salt thereof: (wherein R1, R2, and R3 simultaneously or separately represent a lower alkyl, lower alkenyl, lower alkynyl, aralkyl, araryl, or phenyl group, or a hydrogen atom).Type: ApplicationFiled: November 12, 2008Publication date: October 14, 2010Applicants: KYOWA HAKKO BIO CO., LTD., MITSUBISHI GAS CHEMICAL CO., LTD.Inventors: Ayako Kamimura, Toshikazu Kamiya, Masahiko Nakano, Kazutoshi Kikkawa
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Publication number: 20100255174Abstract: The invention provides an easy-to-drink beverage that contains citrulline, wherein the generation of bad odors due to storage or heating is suppressed. In particular, the invention provides a beverage that contains citrulline and citric acid, as well as sodium citrate or disodium hydrogen phosphate.Type: ApplicationFiled: November 17, 2008Publication date: October 7, 2010Applicant: KYOWA HAKKO BIO CO., LTD.Inventors: Yasushi Sakai, Takeshi Ikeda, Ayako Kamimura
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Publication number: 20100249028Abstract: An object of the present invention is to provide an oral composition useful for promoting collagen synthesis and the like. The present invention can provide an oral composition containing collagen or gelatin or a degradation product thereof, and hydroxyproline or a salt thereof. The weight ratio of alanine and hydroxyproline contained in the amino acids obtained by hydrolyzing the oral composition is preferably 1:1.5-150.Type: ApplicationFiled: May 30, 2008Publication date: September 30, 2010Applicant: KYOWA HAKKO BIO CO., LTD.Inventors: Ayako Kamimura, Yasushi Sakai, Takeshi Ikeda
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Publication number: 20090062371Abstract: An object of the present invention is to provide an oral preparation for promoting synthesis of tissue collagen, an oral preparation for promoting healing of skin wounds or an oral preparation for preventing or improving skin wrinkles or sagging, which is safe and has an excellent effect. The present invention can provide an oral preparation for promoting synthesis of tissue collagen, an oral preparation for promoting healing of skin wounds or an oral preparation for preventing or improving skin wrinkles or sagging, which comprises hydroxyproline or a salt thereof as an active ingredient.Type: ApplicationFiled: March 23, 2007Publication date: March 5, 2009Applicant: KYOWA HAKKO KOGYO CO., LTD.Inventors: Toshikazu Kamiya, Ayako Kamimura, Yoko Kawada
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Publication number: 20070293559Abstract: Orally administered agents, foods and drinks, feeds, food additives or feed additives for preventing or treating a dry state of the skin accompanied by atopic dermatitis, xeroderma, chapped hand, chapped skin and the like are provided. The present invention can provide orally administered agents, foods and drinks, feeds, food additives or feed additives for preventing or treating a dry state of the skin, which comprise hydroxyproline, an N-acyl derivative of hydroxyproline, especially an N-acetyl derivative, an N-propionyl derivative, an N-butyryl derivative, an N-isobutyryl derivative, or a salt thereof as an active ingredient.Type: ApplicationFiled: September 21, 2005Publication date: December 20, 2007Inventors: Erika Kagami, Koji Morishita, Toshikazu Kamiya, Ayako Kamimura
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Patent number: 7015209Abstract: A hair-growing agent comprising, as active ingredients, one or more members selected from the group consisting of lysophosphatidic acids, and phosphatidic acids wherein the fatty acid residue moiety consists only of straight-chain fatty acid residues having an even number of carbon atoms.Type: GrantFiled: July 21, 2004Date of Patent: March 21, 2006Assignee: Kyowa Hakko Kogyo Co., Ltd.Inventors: Tomoya Takahashi, Ayako Kamimura, Takako Matsuoka