Patents by Inventor Ayako Kamimura

Ayako Kamimura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230263761
    Abstract: An agent for elevating nitric oxide (NO) concentration comprising glutathione or a salt thereof as an active ingredient; an agent for elevating NO concentration comprising glutathione or a salt thereof as an active ingredient for preventing or ameliorating a vascular endothelial malfunction-related symptom, or dilating blood vessels or promoting blood flow by elevating NO concentration; and a method for elevating NO concentration by ingesting glutathione or a salt thereof.
    Type: Application
    Filed: April 11, 2023
    Publication date: August 24, 2023
    Applicant: KYOWA HAKKO BIO CO., LTD.
    Inventors: Masahiko MORITA, Ayako KAMIMURA
  • Patent number: 11654125
    Abstract: An agent for elevating nitric oxide (NO) concentration comprising glutathione or a salt thereof as an active ingredient; an agent for elevating NO concentration comprising glutathione or a salt thereof as an active ingredient for preventing or ameliorating a vascular endothelial malfunction-related symptom, or dilating blood vessels or promoting blood flow by elevating NO concentration; and a method for elevating NO concentration by ingesting glutathione or a salt thereof.
    Type: Grant
    Filed: January 21, 2014
    Date of Patent: May 23, 2023
    Assignee: KYOWA HAKKO BIO CO., LTD.
    Inventors: Masahiko Morita, Ayako Kamimura
  • Publication number: 20200108034
    Abstract: The invention provides citrulline or a salt thereof and glutathione or a salt thereof for use in increasing a ratio of muscle mass to total body weight in a person in conjunction with a resistance workout program, as well as a method of increasing a ratio of muscle mass to total body weight in a person by administering citrulline or a salt thereof and glutathione or a salt thereof to the person in conjunction with a resistance workout program. The citrulline and glutathione or salts thereof are administered daily for a period greater than 7 days, whereas the resistance workout program is administered for at least the entire period during which the two compounds are administered. The muscle mass is measured by a body composition meter.
    Type: Application
    Filed: May 31, 2018
    Publication date: April 9, 2020
    Applicant: KYOWA HAKKO BIO CO., LTD.
    Inventors: Masahiko MORITA, Ayako KAMIMURA, Darryn S. WILLOUGHBY
  • Patent number: 10369185
    Abstract: A composition for enhancement of ability to concentrate and method of improving ability to concentrate using alanylglutamine or a salt of alanylglutamine as an active ingredient.
    Type: Grant
    Filed: May 22, 2015
    Date of Patent: August 6, 2019
    Assignee: Kyowa Hakko Bio Co., Ltd.
    Inventors: Yukihiro Hishida, Takeshi Ikeda, Ryusuke Nakagiri, Ayako Kamimura
  • Publication number: 20170189467
    Abstract: A composition for enhancement of ability to concentrate and method of improving ability to concentrate using alanylglutamine or a salt of alanylglutamine as an active ingredient.
    Type: Application
    Filed: May 22, 2015
    Publication date: July 6, 2017
    Inventors: Yukihiro Hishida, Takeshi Ikeda, Ryusuke Nakagiri, Ayako Kamimura
  • Patent number: 9492494
    Abstract: An object of the present invention is to provide an oral composition useful for promoting collagen synthesis and the like. The present invention can provide an oral composition containing collagen or gelatin or a degradation product thereof, and hydroxyproline or a salt thereof. The weight ratio of alanine and hydroxyproline contained in the amino acids obtained by hydrolyzing the oral composition is preferably 1:1.5-150.
    Type: Grant
    Filed: May 30, 2008
    Date of Patent: November 15, 2016
    Assignee: Kyowa Hakko Bio Co., Ltd.
    Inventors: Ayako Kamimura, Yasushi Sakai, Takeshi Ikeda
  • Patent number: 9480668
    Abstract: The present invention provides a blood flow promoting agent containing citrulline or a salt thereof and capsaicin or capsaicinoids as active ingredients, which is safe even by long-term administration, a food with health claims and a functional food affording such action, particularly, a blood flow promoting agent exhibiting an effective vasodilatory action of capsaicin at a low dose free of irritant property, which can be applied to improvement of athletic performance exhibited in relation to peripheral vasodilatation, suppression of fat accumulation, improvement of skin quality, as well as securing blood circulation in ischemic disease and the like, relaxation of blood vessel biased to coarctation due to advancing age, lifestyle-related diseases and the like, prophylaxis of arteriosclerosis, and prophylaxis of stiff neck, feeling of cold, erectile dysfunction, thrombosis and the like due to blood flow disorder.
    Type: Grant
    Filed: November 5, 2013
    Date of Patent: November 1, 2016
    Assignee: Kyowa Hakko Bio Co., Ltd.
    Inventors: Masahiko Morita, Ayako Kamimura, Yoshinori Kobayashi
  • Patent number: 9433605
    Abstract: An object of the present invention is to provide an oral preparation for promoting synthesis of tissue collagen, an oral preparation for promoting healing of skin wounds or an oral preparation for preventing or improving skin wrinkles or sagging, which is safe and has an excellent effect. The present invention can provide an oral preparation for promoting synthesis of tissue collagen, an oral preparation for promoting healing of skin wounds or an oral preparation for preventing or improving skin wrinkles or sagging, which comprises hydroxyproline or a salt thereof as an active ingredient.
    Type: Grant
    Filed: April 4, 2013
    Date of Patent: September 6, 2016
    Assignee: KYOWA HAKKO BIO CO., LTD.
    Inventors: Toshikazu Kamiya, Ayako Kamimura, Yoko Kawada
  • Patent number: 9375479
    Abstract: The invention provides an easy-to-drink beverage that contains citrulline, wherein the generation of bad odors due to storage or heating is suppressed. In particular, the invention provides a beverage that contains citrulline, citric acid, sodium citrate, water, and one or more supplements that are saccharides, souring agents, preservatives, colorants, flavoring agents, functional ingredients, or carbon dioxide.
    Type: Grant
    Filed: February 7, 2014
    Date of Patent: June 28, 2016
    Assignee: Kyowa Hakko Bio Co., Ltd.
    Inventors: Yasushi Sakai, Takeshi Ikeda, Ayako Kamimura
  • Publication number: 20150352067
    Abstract: An agent for elevating nitric oxide (NO) concentration comprising glutathione or a salt thereof as an active ingredient; an agent for elevating NO concentration comprising glutathione or a salt thereof as an active ingredient for preventing or ameliorating a vascular endothelial malfunction-related symptom, or dilating blood vessels or promoting blood flow by elevating NO concentration; and a method for elevating NO concentration by ingesting glutathione or a salt thereof.
    Type: Application
    Filed: January 21, 2014
    Publication date: December 10, 2015
    Inventors: Masahiko MORITA, Ayako KAMIMURA
  • Publication number: 20150297546
    Abstract: The present invention provides a blood flow promoting agent containing citrulline or a salt thereof and capsaicin or capsaicinoids as active ingredients, which is safe even by long-term administration, a food with health claims and a functional food affording such action, particularly, a blood flow promoting agent exhibiting an effective vasodilatory action of capsaicin at a low dose free of irritant property, which can be applied to improvement of athletic performance exhibited in relation to peripheral vasodilatation, suppression of fat accumulation, improvement of skin quality, as well as securing blood circulation in ischemic disease and the like, relaxation of blood vessel biased to coarctation due to advancing age, lifestyle-related diseases and the like, prophylaxis of arteriosclerosis, and prophylaxis of stiff neck, feeling of cold, erectile dysfunction, thrombosis and the like due to blood flow disorder.
    Type: Application
    Filed: November 5, 2013
    Publication date: October 22, 2015
    Inventors: Masahiko MORITA, Ayako KAMIMURA, Yoshinori KOBAYASHI
  • Publication number: 20140179783
    Abstract: The invention provides an easy-to-drink beverage that contains citrulline, wherein the generation of bad odors due to storage or heating is suppressed. In particular, the invention provides a beverage that contains citrulline, citric acid, sodium citrate, water, and one or more supplements that are saccharides, souring agents, preservatives, colorants, flavoring agents, functional ingredients, or carbon dioxide.
    Type: Application
    Filed: February 7, 2014
    Publication date: June 26, 2014
    Applicant: Kyowa Hakko Bio Co., Ltd.
    Inventors: Yasushi SAKAI, Takeshi IKEDA, Ayako KAMIMURA
  • Patent number: 8679568
    Abstract: The invention provides an easy-to-drink beverage that contains citrulline, wherein the generation of bad odors due to storage or heating is suppressed. In particular, the invention provides a beverage that contains citrulline and citric acid, as well as sodium citrate or disodium hydrogen phosphate.
    Type: Grant
    Filed: November 17, 2008
    Date of Patent: March 25, 2014
    Assignee: Kyowa Hakko Bio Co., Ltd.
    Inventors: Yasushi Sakai, Takeshi Ikeda, Ayako Kamimura
  • Patent number: 8575190
    Abstract: The present invention provides a method for preventing or ameliorating skin psoriasis by applying as an active ingredient, a compound represented by general formula (I) or a salt thereof: (wherein R1, R2, and R3 simultaneously or separately represent a lower alkyl, lower alkenyl, lower alkynyl, aralkyl, araryl, or phenyl group, or a hydrogen atom).
    Type: Grant
    Filed: November 12, 2008
    Date of Patent: November 5, 2013
    Assignee: Mitsubishi Gas Chemical Company, Inc.
    Inventors: Ayako Kamimura, Toshikazu Kamiya, Masahiko Nakano, Kazutoshi Kikkawa
  • Publication number: 20100261749
    Abstract: It is an object of the present invention to provide a safe and highly effective preventing or ameliorating agent for skin psoriasis. The present invention provides a preventing or ameliorating agent for skin psoriasis, containing, as an active ingredient, a compound represented by general formula (I) or a salt thereof: (wherein R1, R2, and R3 simultaneously or separately represent a lower alkyl, lower alkenyl, lower alkynyl, aralkyl, araryl, or phenyl group, or a hydrogen atom).
    Type: Application
    Filed: November 12, 2008
    Publication date: October 14, 2010
    Applicants: KYOWA HAKKO BIO CO., LTD., MITSUBISHI GAS CHEMICAL CO., LTD.
    Inventors: Ayako Kamimura, Toshikazu Kamiya, Masahiko Nakano, Kazutoshi Kikkawa
  • Publication number: 20100255174
    Abstract: The invention provides an easy-to-drink beverage that contains citrulline, wherein the generation of bad odors due to storage or heating is suppressed. In particular, the invention provides a beverage that contains citrulline and citric acid, as well as sodium citrate or disodium hydrogen phosphate.
    Type: Application
    Filed: November 17, 2008
    Publication date: October 7, 2010
    Applicant: KYOWA HAKKO BIO CO., LTD.
    Inventors: Yasushi Sakai, Takeshi Ikeda, Ayako Kamimura
  • Publication number: 20100249028
    Abstract: An object of the present invention is to provide an oral composition useful for promoting collagen synthesis and the like. The present invention can provide an oral composition containing collagen or gelatin or a degradation product thereof, and hydroxyproline or a salt thereof. The weight ratio of alanine and hydroxyproline contained in the amino acids obtained by hydrolyzing the oral composition is preferably 1:1.5-150.
    Type: Application
    Filed: May 30, 2008
    Publication date: September 30, 2010
    Applicant: KYOWA HAKKO BIO CO., LTD.
    Inventors: Ayako Kamimura, Yasushi Sakai, Takeshi Ikeda
  • Publication number: 20090062371
    Abstract: An object of the present invention is to provide an oral preparation for promoting synthesis of tissue collagen, an oral preparation for promoting healing of skin wounds or an oral preparation for preventing or improving skin wrinkles or sagging, which is safe and has an excellent effect. The present invention can provide an oral preparation for promoting synthesis of tissue collagen, an oral preparation for promoting healing of skin wounds or an oral preparation for preventing or improving skin wrinkles or sagging, which comprises hydroxyproline or a salt thereof as an active ingredient.
    Type: Application
    Filed: March 23, 2007
    Publication date: March 5, 2009
    Applicant: KYOWA HAKKO KOGYO CO., LTD.
    Inventors: Toshikazu Kamiya, Ayako Kamimura, Yoko Kawada
  • Publication number: 20070293559
    Abstract: Orally administered agents, foods and drinks, feeds, food additives or feed additives for preventing or treating a dry state of the skin accompanied by atopic dermatitis, xeroderma, chapped hand, chapped skin and the like are provided. The present invention can provide orally administered agents, foods and drinks, feeds, food additives or feed additives for preventing or treating a dry state of the skin, which comprise hydroxyproline, an N-acyl derivative of hydroxyproline, especially an N-acetyl derivative, an N-propionyl derivative, an N-butyryl derivative, an N-isobutyryl derivative, or a salt thereof as an active ingredient.
    Type: Application
    Filed: September 21, 2005
    Publication date: December 20, 2007
    Inventors: Erika Kagami, Koji Morishita, Toshikazu Kamiya, Ayako Kamimura
  • Patent number: 7015209
    Abstract: A hair-growing agent comprising, as active ingredients, one or more members selected from the group consisting of lysophosphatidic acids, and phosphatidic acids wherein the fatty acid residue moiety consists only of straight-chain fatty acid residues having an even number of carbon atoms.
    Type: Grant
    Filed: July 21, 2004
    Date of Patent: March 21, 2006
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Tomoya Takahashi, Ayako Kamimura, Takako Matsuoka