Patents by Inventor Ayako Nasu

Ayako Nasu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Malto-oligosaccharide derivatives and use thereof
    Patent number: 6939858
    Abstract: The present invention provides a substance which strongly inhibits human ?-amylase and is effective for the prevention and treatment of hyperglycemia, for example, diabetes and the diseases caused thereby, and an ?-amylase inhibitor and a prophylactic or therapeutic agent for hyperglycemia containing the said substance as active principle. Maltoligosaccharide derivatives represented by the following formula: (wherein n is an integer of 0 to 2; m is an integer of 0 to 2; and X represents a hydrogen atom or a hydrophobic group) or their hydrates or physiologically acceptable salts are provided, and they are contained as active principle to prepare an ?-amylase inhibitor and a prophylactic or therapeutic agent for hyperglycemia such as diabetes.
    Type: Grant
    Filed: June 1, 2001
    Date of Patent: September 6, 2005
    Assignee: Kikkoman Corporation
    Inventors: Riichiro Uchida, Ayako Nasu
  • Malto-oligosaccharide derivatives and use thereof
    Publication number: 20040006046
    Abstract: The present invention provides a substance which strongly inhibits human &agr;-amylase and is effective for the prevention and treatment of hyperglycemia, for example, diabetes and the diseases caused thereby, and an &agr;-amylase inhibitor and a prophylactic or therapeutic agent for hyperglycemia containing the said substance as active principle.
    Type: Application
    Filed: December 6, 2002
    Publication date: January 8, 2004
    Inventors: Riichiro Uchida, Ayako Nasu
  • Malto-oligosaccharide derivatives and uses thereof
    Patent number: 6596696
    Abstract: Maltoligosaccharide derivatives represented by the general formula: wherein n is an integer of 0 to 3 and X is a hydrogen atom or a hydrophobic group) or their hydrates or physiologically acceptable salts, and an &agr;-amylase inhibitor and a prophylactic or therapeutic agent for hyperglycemia such as diabetes containing them as an active ingredient.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: July 22, 2003
    Assignee: Kikkoman Corporation
    Inventors: Riichiro Uchida, Ayako Nasu, Yukihiko Iwai, Takao Someya, Koichiro Tobe
  • Process for preparation of N.sup.6 -substituted 3',5'-cyclic adenosine monophosphate and salt thereof
    Patent number: 4751293
    Abstract: A method for the preparation of an N.sup.6 -substituted 3',5'-cyclic adenosine monophosphate or a salt thereof represented by the general formula ##STR1## wherein R.sub.1 represents a straight chain or branched chain alkyl group of 1 to 13 carbon atoms or an aromatic group and B.sym. represents a hydrogen ion or an alkali metal ion, which comprises allowing a 3',5'-cyclic adenosine monophosphate or a salt thereof represented by the general formula ##STR2## wherein A.sym. represents a hydrogen ion, alkali metal ion, organic ammonium ion, or ammonium ion, to react with an aldehyde represented by the general formulaR.sub.1 CHO (III)wherein R.sub.1 is as defined above, under the conditions such that pH is 7.0 or below, the temperature is -10.degree. to 120.degree. C., and the molar ratio of the compound (II) to the compound (III) is 1:1-40, and reducing the resulting compound with a metal hydride or nascent hydrogen.
    Type: Grant
    Filed: April 25, 1985
    Date of Patent: June 14, 1988
    Assignee: Kikkoman Corporation
    Inventors: Shigehiro Kataoka, Ayako Nasu, Nobuyuki Yamaji, Motohiko Kato