Patents by Inventor Ayako OTANI

Ayako OTANI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10774234
    Abstract: The present invention is to provide a cell culture vessel comprising a copolymer which contains a recurring unit containing an organic group of the following formula (a) and a recurring unit containing an organic group of the following formula (b) being coated onto a surface thereof, a method for manufacturing the same and a method for manufacturing a cell aggregate using the same (wherein Ua1, Ua2, Ub1, Ub2 and Ub3, and An? are as defined in the present specification and the claims).
    Type: Grant
    Filed: June 9, 2014
    Date of Patent: September 15, 2020
    Assignee: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Ayako Otani, Taito Nishino, Yoshiomi Hiroi, Takahiro Kishioka, Tomoyuki Ozawa
  • Publication number: 20200208101
    Abstract: The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition wherein indeterminate structures are formed in a liquid medium, the structures are uniformly dispersed in the solution and substantially retain the cells and/or tissues without substantially increasing the viscosity of the solution, thus affording an effect of preventing sedimentation thereof, and the like
    Type: Application
    Filed: February 26, 2020
    Publication date: July 2, 2020
    Applicants: Nissan Chemical Industries, Ltd., Kyoto University
    Inventors: Taito NISHINO, Tatsuro KANAKI, Ayako OTANI, Koichiro SARUHASHI, Misayo Tomura, Takehisa IWAMA, Masato HORIKAWA, Norio NAKATSUJI, Tomomi OTSUJI
  • Publication number: 20200095542
    Abstract: The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition having an effect of preventing sedimentation of cells and/or tissues, which is afforded by substantially retaining the cells and/or tissues without substantially increasing the viscosity of the solution by nanofibers which have been added to the solution and uniformly dispersed in the liquid medium, and the like.
    Type: Application
    Filed: October 24, 2019
    Publication date: March 26, 2020
    Applicant: NISSAN CHEMICAL CORPORATION
    Inventors: Hisato HAYASHI, Misayo OTANI, Koichiro SARUHASHI, Taito NISHINO, Takehisa IWAMA, Tatsuro KANAKI, Ayako AIHARA
  • Patent number: 10590380
    Abstract: The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition wherein indeterminate structures are formed in a liquid medium, the structures are uniformly dispersed in the solution and substantially retain the cells and/or tissues without substantially increasing the viscosity of the solution, thus affording an effect of preventing sedimentation thereof, and the like.
    Type: Grant
    Filed: March 2, 2017
    Date of Patent: March 17, 2020
    Assignees: Nissan Chemical Industries, Ltd., Kyoto University
    Inventors: Taito Nishino, Tatsuro Kanaki, Ayako Otani, Koichiro Saruhashi, Misayo Tomura, Takehisa Iwama, Masato Horikawa, Norio Nakatsuji, Tomomi Otsuji
  • Patent number: 10519419
    Abstract: The present invention provides a production method of a medium composition, including previously removing divalent metal cations contained in a polymer compound having an anionic functional group, preparing a dry powder of the polymer compound, and mixing the dry powder and the medium, and the like. The present invention also provides a purification method of a polymer compound having an anionic functional group, which includes mixing a suspension of the polymer compound having an anionic functional group in water and a cation exchanger that exchanges a divalent metal cation with a monovalent metal cation to give a polymer compound having an anionic functional group, which shows a reduced amount of contaminating divalent metal cations.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: December 31, 2019
    Assignee: NISSAN CHEMICAL CORPORATION
    Inventors: Misayo Otani, Koichiro Saruhashi, Taito Nishino, Ayako Aihara, Hisashi Ishii, Keigo Matsumoto
  • Patent number: 10487308
    Abstract: The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition having an effect of preventing sedimentation of cells and/or tissues, which is afforded by substantially retaining the cells and/or tissues without substantially increasing the viscosity of the solution by nanofibers which have been added to the solution and uniformly dispersed in the liquid medium, and the like.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: November 26, 2019
    Assignee: NISSAN CHEMICAL CORPORATION
    Inventors: Hisato Hayashi, Misayo Otani, Koichiro Saruhashi, Taito Nishino, Takehisa Iwama, Tatsuro Kanaki, Ayako Aihara
  • Patent number: 10240122
    Abstract: A composition for producing a fiber, containing (A) a polymer compound containing a unit structure represented by the formula (1) and a unit structure represented by the formula (2), (B) a crosslinking agent, (C) an acid compound, and (D) a solvent wherein each symbol in the formulas (1) and (2) is as described in the DESCRIPTION.
    Type: Grant
    Filed: February 13, 2015
    Date of Patent: March 26, 2019
    Assignees: NISSAN CHEMICAL INDUSTRIES, LTD., KYOTO UNIVERSITY
    Inventors: Makiko Umezaki, Takahiro Kishioka, Taito Nishino, Ayako Otani, Kenichiro Kamei, Li Liu, Yong Chen
  • Patent number: 10092687
    Abstract: This is to provide a blood filter comprising a porous element; and a copolymer which exists in at least a part of a surface of the porous element, and which contains a recurring unit containing an organic group of the following formula (a) and a recurring unit containing an organic group of the following formula (b), wherein Ua1, Ua2, Ub1, Ub2 and Ub3, and An? are as defined in the present specification and the claims.
    Type: Grant
    Filed: June 9, 2014
    Date of Patent: October 9, 2018
    Assignee: Nissan Chemical Industries, Ltd.
    Inventors: Tatsuro Kanaki, Takahiro Kishioka, Taito Nishino, Yoshiomi Hiroi, Ayako Otani, Tomoyuki Ozawa
  • Publication number: 20180136196
    Abstract: The invention provides a medium additive, medium composition and a culture method and the like, capable of efficiently culturing cells or tissues in a well dispersed state, and further, permitting cell image analysis of the cells or tissues. The medium additive or medium composition contains agar, which preferably is a low molecular weight agar having a weight average molecular weight of 10,000-60,000. Using same, cells or tissues can be cultured in a well-dispersed state in a medium, and a proliferation promoting effect for the cells or tissues can also be obtained. In addition, the cells can be cultured in any of a floating state and a precipitated state by adjusting the concentration of the aforementioned agar.
    Type: Application
    Filed: April 15, 2016
    Publication date: May 17, 2018
    Applicant: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Natsuki ABE, Taito NISHINO, Ayako OTANI
  • Patent number: 9957644
    Abstract: The invention provides a composition for the production of a fiber having organic solvent resistance, a fiber obtained by spinning the composition, and a biocompatible material containing the fiber. The composition contains (A) a polymer compound containing a unit structure represented by the formula (1) wherein each symbol is as described herein, (B) a crosslinking agent, (C) an acid compound, and (D) a solvent.
    Type: Grant
    Filed: August 29, 2014
    Date of Patent: May 1, 2018
    Assignee: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Makiko Umezaki, Takahiro Kishioka, Taito Nishino, Ayako Otani
  • Publication number: 20170175077
    Abstract: The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition wherein indeterminate structures are formed in a liquid medium, the structures are uniformly dispersed in the solution and substantially retain the cells and/or tissues without substantially increasing the viscosity of the solution, thus affording an effect of preventing sedimentation thereof, and the like
    Type: Application
    Filed: March 2, 2017
    Publication date: June 22, 2017
    Applicants: Nissan Chemical Industries, Ltd., Kyoto University
    Inventors: Taito NISHINO, Tatsuro KANAKI, Ayako OTANI, Koichiro SARUHASHI, Misayo Tomura, Takehisa IWAMA, Masato HORIKAWA, Norio NAKATSUJI, Tomomi OTSUJI
  • Patent number: 9664671
    Abstract: The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition wherein indeterminate structures are formed in a liquid medium, the structures are uniformly dispersed in the solution and substantially retain the cells and/or tissues without substantially increasing the viscosity of the solution, thus affording an effect of preventing sedimentation thereof, and the like.
    Type: Grant
    Filed: July 24, 2013
    Date of Patent: May 30, 2017
    Assignees: Nissan Chemical Industries, Ltd., Kyoto University
    Inventors: Taito Nishino, Tatsuro Kanaki, Ayako Otani, Koichiro Saruhashi, Misayo Tomura, Takehisa Iwama, Masato Horikawa, Norio Nakatsuji, Tomomi Otsuji
  • Publication number: 20170044491
    Abstract: A composition for producing a fiber, containing (A) a polymer compound containing a unit structure represented by the formula (1) and a unit structure represented by the formula (2), (B) a crosslinking agent, (C) an acid compound, and (D) a solvent wherein each symbol in the formulas (1) and (2) is as described in the DESCRIPTION.
    Type: Application
    Filed: February 13, 2015
    Publication date: February 16, 2017
    Applicants: NISSAN CHEMICAL INDUSTRIES, LTD., KYOTO UNIVERSITY
    Inventors: Makiko UMEZAKI, Takahiro KISHIOKA, Taito NISHINO, Ayako OTANI, Kenichiro KAMEI, Li LIU, Yong CHEN
  • Publication number: 20160305044
    Abstract: The invention provides a fiber which is superior in safety, can be conveniently produced, and has organic solvent resistance, as well as a starting material composition for producing the fiber and a biocompatible material containing the fiber. The fiber is produced by spinning a composition containing (A) a condensation product obtained by condensing one or more kinds of a compound represented by the formula (1), and (B) an acid compound: wherein each symbol is as defined herein.
    Type: Application
    Filed: December 19, 2014
    Publication date: October 20, 2016
    Applicant: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Takahiro KISHIOKA, Makiko UMEZAKI, Ayako OTANI
  • Publication number: 20160201226
    Abstract: The invention provides a composition for the production of a fiber having organic solvent resistance, a fiber obtained by spinning the composition, and a biocompatible material containing the fiber. The composition contains (A) a polymer compound containing a unit structure represented by the formula (1) wherein each symbol is as described herein, (B) a crosslinking agent, (C) an acid compound, and (D) a solvent.
    Type: Application
    Filed: August 29, 2014
    Publication date: July 14, 2016
    Applicant: NISSAN CHEMICAL INDUSTRIES, LTD.
    Inventors: Makiko UMEZAKI, Takahiro KISHIOKA, Taito NISHINO, Ayako OTANI
  • Publication number: 20160129176
    Abstract: This is to provide a blood filter comprising a porous element; and a copolymer which exists in at least a part of a surface of the porous element, and which contains a recurring unit containing an organic group of the following formula (a) and a recurring unit containing an organic group of the following formula (b), wherein Ua1, Ua2, Ub1, Ub2 and Ub3, and An? are as defined in the present specification and the claims.
    Type: Application
    Filed: June 9, 2014
    Publication date: May 12, 2016
    Inventors: Tatsuro KANAKI, Takahiro KISHIOKA, Taito NISHINO, Yoshiomi HIROI, Ayako OTANI, Tomoyuki OZAWA
  • Publication number: 20160122576
    Abstract: This is to provide a coating film having a function of inhibiting adhesion of a biological substance, a method for manufacturing the coating film, a copolymer obtainable by polymerizing a specific monomer mixture, a composition for forming a coating film having a specific composition, a method for manufacturing a varnish containing a copolymer to be used as a raw material of the composition for forming a coating film which is used for forming said film, and a sol for forming the coating film. In particular, this is to provide a coating film obtained by the method comprising a process of applying a composition for forming a coating film which comprises a copolymer comprising a recurring unit containing an organic group of the formula (a) and a recurring unit containing an organic group of the formula (b) and a solvent onto a substrate; and a process of drying at a temperature of ?200° C. to 200° C. (wherein Ua1, Ua2, Ub1, Ub2 and Ub3, and An? are as defined in the present specification and the claims).
    Type: Application
    Filed: June 9, 2014
    Publication date: May 5, 2016
    Inventors: Yoshiomi HIROI, Ayako OTANI, Takahiro KISHIOKA, Taito NISHINO, Tomoyuki OZAWA
  • Publication number: 20160115435
    Abstract: The present invention is to provide a cell culture vessel comprising a copolymer which contains a recurring unit containing an organic group of the following formula (a) and a recurring unit containing an organic group of the following formula (b) being coated onto a surface thereof, a method for manufacturing the same and a method for manufacturing a cell aggregate using the same (wherein Ua1, Ua2, Ub1, Ub2 and Ub3, and An? are as defined in the present specification and the claims).
    Type: Application
    Filed: June 9, 2014
    Publication date: April 28, 2016
    Inventors: Ayako OTANI, Taito NISHINO, Yoshiomi HIROI, Takahiro KISHIOKA, Tomoyuki OZAWA
  • Publication number: 20160060601
    Abstract: The present invention provides a method of producing erythrocytes, including efficiently differentiating hematopoietic stem cells and/or a hematopoietic progenitor cells into erythrocytes by using a medium composition having an effect of homogeneously dispersing the hematopoietic stem cells and/or the hematopoietic progenitor cells and maintaining a floating state.
    Type: Application
    Filed: April 16, 2014
    Publication date: March 3, 2016
    Inventors: Taito NISHINO, Tatsuro KANAKI, Ayako OTANI, Koichiro SARUHASHI, Misayo TOMURA
  • Publication number: 20140106348
    Abstract: The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition wherein indeterminate structures are formed in a liquid medium, the structures are uniformly dispersed in the solution and substantially retain the cells and/or tissues without substantially increasing the viscosity of the solution, thus affording an effect of preventing sedimentation thereof, and the like.
    Type: Application
    Filed: July 24, 2013
    Publication date: April 17, 2014
    Inventors: Taito NISHINO, Tatsuro KANAKI, Ayako OTANI, Koichiro SARUHASHI, Misayo Tomura, Takehisa IWAMA, Masato HORIKAWA, Norio NAKATSUJI, Tomomi OTSUJI