Patents by Inventor Ayan Dey

Ayan Dey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Constructing a DNA chimera for vaccine development against leishmaniasis and tuberculosis
    Patent number: 8299232
    Abstract: A novel recombinant chimera of DNA construct having esat-6 region of Mycobacterium tuberculosis and kinesin region of Leishmania donovani cloned together on two sides of self cleaving peptide in a DNA vaccine vector pVAX-1 wherein the chimeric construct is operatively linked to a transcriptional promoter thus capable of self replication and expression within the mammalian cell, and the process of preparation thereof comprising: analysis of the predicted protein sequence of kinesin motor domain and esat-6 domain using Promiscuous MHC Class-1 Binding Peptide Prediction Servers; amplification of gene coding for kinesin motor domain and esat-6 domain; cloning of kinesin esat-6 gene region in pGEM-T™ vector for sequence analysis; generation of chimeric construct by directional cloning in pVAX-1 vector.
    Type: Grant
    Filed: February 10, 2009
    Date of Patent: October 30, 2012
    Assignees: Department of Biotechnology, All India Institute of Medical Science
    Inventors: Sarman Singh, Ayan Dey
  • Constructing a DNA Chimera for Vaccine Development Against Leishmaniasis and Tuberculosis
    Publication number: 20110150932
    Abstract: A novel recombinant chimera of DNA construct having esat-6 region of Mycobacterium tuberculosis and kinesin region of Leishmania donovani cloned together on two sides of self cleaving peptide in a DNA vaccine vector pVAX-1 wherein the chimeric construct is operatively linked to a transcriptional promoter thus capable of self replication and expression within the mammalian cell, and the process of preparation thereof comprising: analysis of the predicted protein sequence of kinesin motor domain and esat-6 domain using Promiscuous MHC Class-1 Binding Peptide Prediction Servers; amplification of gene coding for kinesin motor domain and esat-6 domain; cloning of kinesin esat-6 gene region in pGEM-T™ vector for sequence analysis; generation of chimeric construct by directional cloning in pVAX-1 vector.
    Type: Application
    Filed: February 10, 2009
    Publication date: June 23, 2011
    Applicants: DEPARTMENT OF BIOTECHNOLOGY, ALL INDIA INSTITUTE OF MEDICAL SCIENCE
    Inventors: Sarman Singh, Ayan Dey