Patents by Inventor Ayato TAGAWA

Ayato TAGAWA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11389803
    Abstract: Disclosed is a liquid sending method for sending liquid to a sample processing chip having a flow path formed therein, the method including: measuring a flow of a second liquid which is different from a first liquid which is introduced into the flow path in the sample processing chip; controlling the flow of the second liquid on the basis of the measured flow; and introducing the first liquid into the flow path in the sample processing chip by means of the second liquid of which flow is controlled.
    Type: Grant
    Filed: February 26, 2018
    Date of Patent: July 19, 2022
    Assignee: SYSMEX CORPORATION
    Inventors: Kunpeng Cai, Koya Yamawaki, Yasuko Kawamoto, Katsumi Nakanishi, Ayato Tagawa
  • Patent number: 11325120
    Abstract: This specimen treatment chip includes: a first fluid module having a first flow channel for performing a first treatment step on an object component in a specimen; a second fluid module having a second flow channel for performing a second treatment step on the object component subjected to the first treatment step; a substrate; and a connection flow channel for connecting the first fluid module and the second fluid module disposed on the substrate.
    Type: Grant
    Filed: April 6, 2018
    Date of Patent: May 10, 2022
    Assignee: SYSMEX CORPORATION
    Inventors: Ayato Tagawa, Tsuyoshi Nakano, Yasuko Kawamoto, Koya Yamawaki, Hiroaki Tobimatsu
  • Patent number: 11285077
    Abstract: A blood collection device including a flow path to flow blood by capillary action capable of collecting a large amount of blood is provided. The blood collection device includes an introduction inlet 23 for introducing the blood of the subject M, a substrate 20 connected to the introduction inlet 23 and including a flow path 25 to flow the blood by capillary action, and a cooling body 30 for cooling the flow path 25.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: March 29, 2022
    Assignee: SYSMEX CORPORATION
    Inventors: Ayato Tagawa, Junko Kojima, Nobuyasu Hori, Kenji Akama, Masaya Okada, Kunpeng Cai, Samiko Hosoya, Shigeki Iwanaga
  • Publication number: 20210394184
    Abstract: To shorten the time required to sort target particles with sufficient purity, a particle sorter is provided.
    Type: Application
    Filed: June 16, 2021
    Publication date: December 23, 2021
    Applicant: SYSMEX CORPORATION
    Inventors: Kunpeng Cai, Shruti Mankar, Anastasia Maslova, Taiga Ajirl, Yumiko Sakai, Shunsuke Watanabe, Tasuku Yotoriyama, Ayato Tagawa, Takehiro Hasegawa, Yoshiaki Miyamoto
  • Patent number: 10620108
    Abstract: Disclosed is a method of processing a specimen in which a target component in a specimen is processed using a specimen processing chip provided with a flow-path, the method including: introducing a fluid into a flow-path to form an interface that divides the fluid from a process liquid used for the processing of the target component with a rim of the interface on an inner wall of the flow-path, the process liquid containing particles including the target component; and moving the formed interface along the flow-path with the rim of the interface on the inner wall so as to force out the particles retained in the process liquid by the fluid.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: April 14, 2020
    Assignee: SYSMEX CORPORATION
    Inventors: Yasuko Kawamoto, Ayato Tagawa
  • Publication number: 20190285520
    Abstract: A sample processing method comprises storing a processing liquid (11) containing a target component (10) and a diluent (12) for diluting the processing liquid (11) in a reservoir (110) of a sample processing chip (100), and agitating the processing liquid (11) and the diluent (12) in the reservoir (110) by introducing a gas into the reservoir (110). The processing liquid (11) is diluted in order to prepare a droplet forming sample (13) for forming droplets (14) individually encapsulating the target component (10).
    Type: Application
    Filed: March 13, 2019
    Publication date: September 19, 2019
    Inventors: Koya YAMAWAKI, Kichitarou NAKAJIMA, Katsumi NAKANISHI, Yasuko KAWAMOTO, Ayato TAGAWA
  • Patent number: 10173217
    Abstract: Disclosed is a sample processing method for processing a target component in a sample by use of a sample processing chip having a storage portion and a droplet forming flow path, the sample processing method including: storing, in the storage portion, a mixture of the target component and a predetermined amount of a diluent for causing the target component to be encapsulated by one molecule or by one particle into a droplet; heating the mixture in the storage portion to cause thermal convection in the storage portion thereby to mix the target component and the diluent together; and in the droplet forming flow path, forming droplets in a dispersion medium, each droplet containing the diluted target component and a reagent that reacts with the target component.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: January 8, 2019
    Assignee: SYSMEX CORPORATION
    Inventors: Koya Yamawaki, Ayato Tagawa, Tsuyoshi Nakano
  • Publication number: 20180243744
    Abstract: Disclosed is a liquid sending method for sending liquid to a sample processing chip having a flow path formed therein, the method including: measuring a flow of a second liquid which is different from a first liquid which is introduced into the flow path in the sample processing chip; controlling the flow of the second liquid on the basis of the measured flow; and introducing the first liquid into the flow path in the sample processing chip by means of the second liquid of which flow is controlled.
    Type: Application
    Filed: February 26, 2018
    Publication date: August 30, 2018
    Inventors: Kunpeng CAI, Koya YAMAWAKI, Yasuko KAWAMOTO, Katsumi NAKANISHI, Ayato TAGAWA
  • Publication number: 20180221878
    Abstract: This specimen treatment chip includes: a first fluid module having a first flow channel for performing a first treatment step on an object component in a specimen; a second fluid module having a second flow channel for performing a second treatment step on the object component subjected to the first treatment step; a substrate; and a connection flow channel for connecting the first fluid module and the second fluid module disposed on the substrate.
    Type: Application
    Filed: April 6, 2018
    Publication date: August 9, 2018
    Inventors: Ayato TAGAWA, Tsuyoshi NAKANO, Yasuko KAWAMOTO, Koya YAMAWAKI, Hiroaki TOBIMATSU
  • Publication number: 20180221881
    Abstract: The present specimen treatment chip includes: a first flow channel for forming a droplet containing a mixed liquid of a nucleic acid, a reagent for an amplification reaction of the nucleic acid, and a carrier to which a primer for binding to the nucleic acid is added, in a dispersion medium; a second flow channel for amplifying the nucleic acid in the droplet; and a third flow channel for mixing the droplet containing the carrier with the primer having bound to an amplification product of the nucleic acid, and a reagent for breaking down the droplet, to break down the droplet.
    Type: Application
    Filed: April 6, 2018
    Publication date: August 9, 2018
    Inventors: Ayato TAGAWA, Tsuyoshi NAKANO, Yasuko KAWAMOTO, Koya YAMAWAKI, Hiroaki TOBIMATSU
  • Publication number: 20180149566
    Abstract: Disclosed is a specimen treatment apparatus that treats a specimen by using a specimen treatment chip including a flow channel and a connecting port communicating with the flow channel, the specimen treatment apparatus including: a placement part in which the specimen treatment chip is placed; a connector provided to be engaged with the connecting port to allow a sample containing a specimen to be injected into the flow channel through the connector; and a heating unit that is pressed on the specimen treatment chip and heats the specimen treatment chip while the connector is connected to the connecting port of the specimen treatment chip placed in the placement part.
    Type: Application
    Filed: November 29, 2017
    Publication date: May 31, 2018
    Inventors: Tsuyoshi NAKANO, Koya YAMAWAKI, Ayato TAGAWA
  • Publication number: 20180149574
    Abstract: Disclosed is a method of processing a specimen in which a target component in a specimen is processed using a specimen processing chip provided with a flow-path, the method including: introducing a fluid into a flow-path to form an interface that divides the fluid from a process liquid used for the processing of the target component with a rim of the interface on an inner wall of the flow-path, the process liquid containing particles including the target component; and moving the formed interface along the flow-path with the rim of the interface on the inner wall so as to force out the particles retained in the process liquid by the fluid.
    Type: Application
    Filed: November 29, 2017
    Publication date: May 31, 2018
    Inventors: Yasuko KAWAMOTO, Ayato TAGAWA
  • Patent number: 9885661
    Abstract: Disclosed is an analyte detection method for detecting an analyte contained in a biological sample, constituted by irradiating a light of a first peak wavelength on a complex containing an analyte and fluorescent substance which gives off light of a second peak wavelength of 450 nm or higher but not exceeding 900 nm when irradiated with light of the first wavelength of 190 nm or higher but not exceeding 350 nm, detecting the light of the second peak wavelength given off by the fluorescent substance when irradiated by light of the first peak wavelength, by a photodetector, wherein the photodetector has a quantum efficiency in the second peak wavelength that is two or more times the quantum efficiency in the first peak wavelength.
    Type: Grant
    Filed: October 7, 2014
    Date of Patent: February 6, 2018
    Assignee: SYSMEX CORPORATION
    Inventors: Ayato Tagawa, Hiroya Kirimura
  • Publication number: 20180021219
    Abstract: A blood collection device including a flow path to flow blood by capillary action capable of collecting a large amount of blood is provided. The blood collection device includes an introduction inlet 23 for introducing the blood of the subject M, a substrate 20 connected to the introduction inlet 23 and including a flow path 25 to flow the blood by capillary action, and a cooling body 30 for cooling the flow path 25.
    Type: Application
    Filed: July 19, 2017
    Publication date: January 25, 2018
    Inventors: Ayato TAGAWA, Junko KOJIMA, Nobuyasu HORI, Kenji AKAMA, Masaya OKADA, Kunpeng CAI, Samiko HOSOYA, Shigeki IWANAGA
  • Publication number: 20170259266
    Abstract: Disclosed is a sample processing method for processing a target component in a sample by use of a sample processing chip having a storage portion and a droplet forming flow path, the sample processing method including: storing, in the storage portion, a mixture of the target component and a predetermined amount of a diluent for causing the target component to be encapsulated by one molecule or by one particle into a droplet; heating the mixture in the storage portion to cause thermal convection in the storage portion thereby to mix the target component and the diluent together; and in the droplet forming flow path, forming droplets in a dispersion medium, each droplet containing the diluted target component and a reagent that reacts with the target component.
    Type: Application
    Filed: March 9, 2017
    Publication date: September 14, 2017
    Inventors: Koya YAMAWAKI, Ayato TAGAWA, Tsuyoshi NAKANO
  • Publication number: 20160061730
    Abstract: Disclosed is an embodiment of a fluorescence detection apparatus comprises a photodetector that detects a plurality of colors of light; a light filter member on or above the photodetector that transmits light at or above a predefined wavelength and that cuts off light with a wavelength included in a wavelength band below the predefined wavelength, the predefined wavelength being included in a wavelength band being a sensitivity range of the photodetector; an irradiator that irradiates a fluorescent substance on the light filter member, with excitation light with a peak wavelength included in the wavelength band below the predefined wavelength; and a first correction unit that compensates for a signal of light cut off by the light filter member out of fluorescence emitted from the fluorescent substance in response to irradiation from the excitation light.
    Type: Application
    Filed: August 27, 2015
    Publication date: March 3, 2016
    Inventor: Ayato TAGAWA
  • Publication number: 20150104880
    Abstract: Disclosed is an analyte detection method for detecting an analyte contained in a biological sample, constituted by irradiating a light of a first peak wavelength on a complex containing an analyte and fluorescent substance which gives off light of a second peak wavelength of 450 nm or higher but not exceeding 900 nm when irradiated with light of the first wavelength of 190 nm or higher but not exceeding 350 nm, detecting the light of the second peak wavelength given off by the fluorescent substance when irradiated by light of the first peak wavelength, by a photodetector, wherein the photodetector has a quantum efficiency in the second peak wavelength that is two or more times the quantum efficiency in the first peak wavelength.
    Type: Application
    Filed: October 7, 2014
    Publication date: April 16, 2015
    Inventors: Ayato TAGAWA, Hiroya KIRIMURA