Patents by Inventor Ayelet CHEN

Ayelet CHEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Engineered dual binding antibodies and uses thereof
    Patent number: 12686714
    Abstract: Described herein are engineered dual binding antibodies that bind to IL-13 and TSLP and uses thereof. Uses include treating allergic and respiratory conditions. Described herein are also libraries comprising the engineered dual binding antibodies, and methods of producing the engineered dual binding antibodies and functional and biochemical characterization of the antibodies.
    Type: Grant
    Filed: September 27, 2023
    Date of Patent: July 21, 2026
    Assignee: BIOLOJIC DESIGN LTD.
    Inventors: Alik Demishtein, Shmuel Bernstein, Tomer Shlamkovich, Ayelet Chen, Yehezkel Sasson, Marek Strajbl, Itay Levin, Sharon Fischman, Yanay Ofran, Guy Nimrod, Alexey Shnyder, Hadar Gattegno, Nikol Malchenko, Olga Bluvshtein Yermolaev, Noam Grossman, Liron Danielpur, Itzhak Meir, Morya Ifrach, Reut Barak Fuchs, Michael Zhenin, Yair Fastman
  • ENGINEERED DUAL BINDING ANTIBODIES AND USES THEREOF
    Publication number: 20240409625
    Abstract: Described herein are engineered dual binding antibodies that bind to IL-13 and TSLP and uses thereof. Uses include treating allergic and respiratory conditions. Described herein are also libraries comprising the engineered dual binding antibodies, and methods of producing the engineered dual binding antibodies and functional and biochemical characterization of the antibodies.
    Type: Application
    Filed: September 27, 2023
    Publication date: December 12, 2024
    Applicant: Biolojic Design Ltd.
    Inventors: ALIK DEMISHTEIN, Shmuel BERNSTEIN, Tomer SHLAMKOVICH, Ayelet CHEN, Yehezkel SASSON, Marek STRAJBL, Itay LEVIN, Sharon FISCHMAN, Yanay OFRAN, Guy NIMROD, Alexey SHNYDER, Hadar GATTEGNO, Nikol MALCHENKO, Olga BLUVSHTEIN YERMOLAEV, Noam GROSSMAN, Liron DANIELPUR, Itzhak MEIR, Morya IFRACH, Reut BARAK FUCHS, Michael ZHENIN
  • ENGINEERED DUAL BINDING ANTIBODIES AND USES THEREOF
    Publication number: 20240059769
    Abstract: Described herein are engineered dual binding antibodies that bind to IL-13 and TSLP and uses thereof. Uses include treating allergic and respiratory conditions. Described herein are also libraries comprising the engineered dual binding antibodies, and methods of producing the engineered dual binding antibodies and functional and biochemical characterization of the antibodies.
    Type: Application
    Filed: September 27, 2023
    Publication date: February 22, 2024
    Applicant: Biolojic Design Ltd.
    Inventors: ALIK DEMISHTEIN, Shmuel BERNSTEIN, Tomer SHLAMKOVICH, Ayelet CHEN, Yehezkel SASSON, Marek STRAJBL, Itay LEVIN, Sharon FISCHMAN, Yanay OFRAN, Guy NIMROD, Alexey SHNYDER, Hadar GATTEGNO, Nikol MALCHENKO, Olga BLUVSHTEIN YERMOLAEV, Noam GROSSMAN, Liron DANIELPUR, Itzhak MEIR, Morya IFRACH, Reut BARAK FUCHS, Michael ZHENIN
  • ANTI-TUMOR NECROSIS FACTOR RECEPTOR (TNFR2) ANTIBODIES AND USES THEREOF
    Publication number: 20230167188
    Abstract: The present disclosure describes a number of anti-TNFR2 (tumor necrosis factor receptor 2) antibodies. These antibodies are TNFR2 agonists. In certain cases, these antibodies agonize TNFR2 in an Fc independent manner. These antibodies can modulate the proliferation and/or functions of regulatory T cells and myeloid-derived suppressor cells. In certain instances, these antibodies can be used to treat diseases such as GvHD or autoimmune diseases.
    Type: Application
    Filed: July 1, 2021
    Publication date: June 1, 2023
    Applicant: Biolojic Design Ltd.
    Inventors: Inbar AMIT, Itay LEVIN, Ayelet CHEN, Tal VANA, Nino OREN, Dor SAMET, Efrat CHOEN ZADA, Natalia LEVITIN, Guy NIMROD, Yehezkel SASSON, Alik DEMISHTEIN, Timothy WYANT, Reut BARAK FUCHS, Yair FASTMAN, Sharon FISCHMAN, Marek STRAJBL, Michael ZHENIN, Olga BLUVSHTEIN YERMOLAEV, Noam GROSSMAN, Oshrat Shir TWITO, Nevet Zur BITON, Liron DANIELPUR, May Sofia BEN MAYOR, Yanay OFRAN