Patents by Inventor Ayelet Dar-Oaknin

Ayelet Dar-Oaknin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PERICYTE PROGENITOR CELLS AND METHODS OF GENERATING AND USING SAME
    Publication number: 20170342384
    Abstract: Provided are methods of isolating pericyte progenitor cells from pluripotent stem cells such as embryonic stem cells and induced pluripotent stem cells, by isolating CD105+, CD73+ and/or CD105+/CD73+ cells from embryoid bodies and optionally by enriching the cells with CD31? cells. Also provided are methods of isolating endothelial cells and co-derivation of pericyte and endothelial cells progenitor cells from embryoid bodies, and methods of differentiating same for various therapeutic applications. In addition, the invention provides an isolated pericyte progenitor cell having an expression marker signature of CD105+/CD73+CD31?/alpha SMA?/CD133?/Flk-1?.
    Type: Application
    Filed: July 24, 2017
    Publication date: November 30, 2017
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Ayelet DAR-OAKNIN, Joseph ITSKOVITZ-ELDOR
  • PERICYTE PROGENITOR CELLS AND METHODS OF GENERATING AND USING SAME
    Publication number: 20120148546
    Abstract: Provided are methods of isolating pericyte progenitor cells from pluripotent stem cells such as embryonic stem cells and induced pluripotent stem cells, by isolating CD105+, CD73+ and/or CD105+/CD73+ cells from embryoid bodies and optionally by enriching the cells with CD31? cells. Also provided are methods of isolating endothelial cells and co-derivation of pericyte and endothelial cells progenitor cells from embryoid bodies, and methods of differentiating same for various therapeutic applications. In addition, the invention provides an isolated pericyte progenitor cell having an expression marker signature of CD105+/CD73+CD31?/alpha SMA?/CD133?/Flk-1?.
    Type: Application
    Filed: August 17, 2010
    Publication date: June 14, 2012
    Applicant: Technion Research & Development Foundation Ltd.
    Inventors: Ayelet Dar-Oaknin, Joseph Itskovitz-Eldor