Abstract: A simple and practical clinical system and method to objectively assess and evaluate patient status and progress in different aspects of gait and functional performance is provided in which a complete functional clinical program that emphasizes the functional parameters relevant to gait or functional performance, such as walking, sit to stand (STS), standing, weight shifting ability, stair-climbing, the heel to toe gait pattern, symmetry in weight bearing, and adequate limb loading patterns is possible in the clinics and at home. An objective therapy regimen personalized to the patient is loaded into a handheld device to guide the patient through the exercises and to monitor compliance. Various forms of encouraging feedback are provided to the patient during the sessions. The therapy regimen may be updated remotely based on the patient's performance.