Abstract: Devices and methods are provided that permit efficient and selective separation of liquid biological specimens into at least two constituent components to facilitate subsequent quantitative and qualitative analysis on at least one analyte of interest in at least one of the components. For example, a liquid biological specimen separation device includes a base defining a base surface, a collection housing extending away from the base surface to a collection end, a collection membrane disposed on the collection housing adjacent the collection end, and a cap assembly secured to the collection housing. The cap assembly includes a cap defining an aperture therein configured to allow deposition of a liquid biological specimen therethrough, a separation membrane secured to the cap and extending across the aperture, a cap ring rotatably secured about the collection housing, and a tether coupling the cap to the cap ring.

Abstract: A betting game in which the winner of a given bet is determined by the numbers which appear on the faces of two thrown die. The individual throwing the dice is deemed the winner of a bet if a particular combination of indicia are found to be facing upward on the dice after they have been cast. Certain other combinations of indicia will result in the player winning the bet. Yet other combinations of indicia result in a higher payout ratio or no winners with a transfer of the dice to another shooter. The game is played upon a the surface of a table with specific demarcations for the various actions involved in the game, such as placing bets, throwing the dice, etc.