Patents by Inventor Ayman Mahmoud

Ayman Mahmoud has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11903987
    Abstract: A plant-based composition containing an alcohol extract of Tecoma species (e.g. Tecoma stans) and an exogenous carrier and/or excipient. Also provided is a composition including a mixture of three acids, namely corosolic acid, oleanolic acid, and ursolic acid, which can be found in the Tecoma species. Methods of treating skin lesions (e.g. warts, corns, calluses, and umbilical granulomas) and reducing symptoms associated with the skin lesions using such compositions are specified.
    Type: Grant
    Filed: May 7, 2021
    Date of Patent: February 20, 2024
    Assignees: National Guard Health Affairs, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center
    Inventor: Ayman Mahmoud Saleh
  • Patent number: 11879000
    Abstract: A method for isolating a protein complex comprising BCL10 and at least one, preferably all, of ROS1, LSD1, BTK, KU80, KU70, CUL4A, IMP3, thioredoxin, hTID1, DAP3, CDK1/CDC2, PRL1/PTP4A1 or NM23. Methods for using this complex to diagnose or prognose diseases including diabetes, obesity, cancer, neurodegenerative disease or inflammatory diseases associated with activation of NF-?B. Methods for distinguishing lean, obese and diabetic subjects based on expression of BCL10 and its ligands are also disclosed. The invention also pertains to pharmaceutical compositions comprising ligands for BCL10 or other components of this complex or agents such as siRNA or miRNA that regulate the expression of the protein components of this complex.
    Type: Grant
    Filed: November 15, 2019
    Date of Patent: January 23, 2024
    Assignees: National Guard Health Affairs, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz City for Science and Technology
    Inventors: Ayman Mahmoud Saleh, Mamoun Ahmad Salim Ahram, Amre Osman Nasr
  • Publication number: 20230332804
    Abstract: A building heating and cooling system includes a structural foundation member that extends into a borehole. A heat exchange loop is installed within the foundation member for heat exchange with ground surrounding the foundation member. The heat exchange hoop is interconnected with a heat pump for providing heating or cooling to the building by heat exchange with ground surrounding the foundation member.
    Type: Application
    Filed: September 14, 2021
    Publication date: October 19, 2023
    Inventors: Seyed Masih Alavy GHAHFARROKHY, Ladislav RAK, Jun WANG, David Ernest SALT, Afroozalsadat ALAVI, Jaroslava Marie-Magdalena PARSLOW, Seth B. DWORKIN, Ayman Mahmoud Bayomy MAHMOUD, Aggrey MWEISGYE, Hiep V. NGUYEN
  • Patent number: 11455808
    Abstract: The invention relates to a method for the classification of parking spaces in a surrounding region of a vehicle with a driver support system, wherein the vehicle comprises at least one first surroundings sensor and a second surroundings sensor, comprising the steps of receiving first sensor data out of the surrounding region by the driver support system from the at least one first surroundings sensor, recognizing a parking-space-like partial region of the surrounding region in the first sensor data, requesting second sensor data acquired by the at least one second surroundings sensor out of the parking-space-like partial region by the driver support system as soon as the parking-space-like partial region is recognized in the first sensor data, transmitting the requested second sensor data to a vehicle-side computing unit comprising a deep neural network (DNN), and classifying the parking-space-like partial region into categories with the DNN, wherein the categories comprise legal, parkable parking spaces and
    Type: Grant
    Filed: December 6, 2018
    Date of Patent: September 27, 2022
    Assignee: Valeo Schalter und Sensoren GmbH
    Inventors: Malte Joos, Mathieu Bulliot, Mahmoud Shalaby, Ayman Mahmoud, Jean-Francois Bariant
  • Publication number: 20210290714
    Abstract: A plant-based composition containing an alcohol extract of Tecoma species (e.g. Tecoma stans) and an exogenous carrier and/or excipient. Also provided is a composition including a mixture of three acids, namely corosolic acid, oleanolic acid, and ursolic acid, which can be found in the Tecoma species. Methods of treating skin lesions (e.g. warts, corns, calluses, and umbilical granulomas) and reducing symptoms associated with the skin lesions using such compositions are specified.
    Type: Application
    Filed: May 7, 2021
    Publication date: September 23, 2021
    Applicants: National Guard Health Affairs, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center
    Inventor: Ayman Mahmoud SALEH
  • Patent number: 11124499
    Abstract: A pharmaceutical composition containing an anti-proliferative compound, named Tecomaphorbide, which is identified and isolated from Tecoma plants (e.g. Tecoma stans). The pharmaceutical composition may contain a derivative and/or a salt of Tecomaphorbide. A process of obtaining Tecomaphorbide from Tecoma plants is specified. A method of treating cancer (e.g. leukemia, lymphoma, breast, colon, and prostate cancer) with the pharmaceutical composition is also provided.
    Type: Grant
    Filed: September 13, 2019
    Date of Patent: September 21, 2021
    Assignees: National Guard Health Affairs, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center
    Inventor: Ayman Mahmoud Saleh
  • Patent number: 11090347
    Abstract: A plant-based composition containing an alcohol extract of Tecoma species (e.g. Tecoma stans) and an exogenous carrier and/or excipient. Also provided is a composition including a mixture of three acids, namely corosolic acid, oleanolic acid, and ursolic acid, which can be found in the Tecoma species. Methods of treating skin lesions (e.g. warts, corns, calluses, and umbilical granulomas) and reducing symptoms associated with the skin lesions using such compositions are specified.
    Type: Grant
    Filed: September 4, 2019
    Date of Patent: August 17, 2021
    Assignees: National Guard Health Affairs, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center
    Inventor: Ayman Mahmoud Saleh
  • Publication number: 20210216797
    Abstract: The invention relates to a method for the classification of parking spaces in a surrounding region of a vehicle with a driver support system, wherein the vehicle comprises at least one first surroundings sensor and a second surroundings sensor, comprising the steps of receiving first sensor data out of the surrounding region by the driver support system from the at least one first surroundings sensor, recognizing a parking-space-like partial region of the surrounding region in the first sensor data, requesting second sensor data acquired by the at least one second surroundings sensor out of the parking-space-like partial region by the driver support system as soon as the parking-space-like partial region is recognized in the first sensor data, transmitting the requested second sensor data to a vehicle-side computing unit comprising a deep neural network (DNN), and classifying the parking-space-like partial region into categories with the DNN, wherein the categories comprise legal, parkable parking spaces and
    Type: Application
    Filed: December 6, 2018
    Publication date: July 15, 2021
    Applicant: Valeo Schalter und Sensoren GmbH
    Inventors: Malte Joos, Mathieu Bulliot, Mahmoud Shalaby, Ayman Mahmoud
  • Publication number: 20210148907
    Abstract: A method for isolated a protein complex comprising BCL10 and at least one, preferably all, of ROS1, LSD1, BTK, KU80, KU70, CUL4A, IMP3, thioredoxin, hTID1, DAP3, CDK1/CDC2, PRL1/PTP4A1 or NM23. Methods for using this complex to diagnose or prognose diseases including diabetes, obesity, cancer, neurodegenerative disease or inflammatory diseases associated with activation of NF-?B Methods for distinguishing lean, obese and diabetic subjects based on expression of BCL10 and its ligands are also disclosed. The invention also pertains to pharmaceutical compositions comprising ligands for BCL10 or other components of this complex or agents such as siRNA or miRNA that regulate the expression of the protein components of this complex.
    Type: Application
    Filed: November 15, 2019
    Publication date: May 20, 2021
    Applicants: National Guard Health Affairs, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz City for Science and Technology
    Inventors: Ayman Mahmoud Saleh, Mamoun Ahmad Salim Ahram, Amre Osman Nasr
  • Publication number: 20200247786
    Abstract: A pharmaceutical composition containing an anti-proliferative compound, named Tecomaphorbide, which is identified and isolated from Tecoma plants (e.g. Tecoma stans). The pharmaceutical composition may contain a derivative and/or a salt of Tecomaphorbide. A process of obtaining Tecomaphorbide from Tecoma plants is specified. A method of treating cancer (e.g. leukemia, lymphoma, breast, colon, and prostate cancer) with the pharmaceutical composition is also provided.
    Type: Application
    Filed: September 13, 2019
    Publication date: August 6, 2020
    Applicants: National Guard Health Affairs, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center
    Inventor: Ayman Mahmoud SALEH
  • Publication number: 20200085894
    Abstract: A plant-based composition containing an alcohol extract of Tecoma species (e.g. Tecoma stans) and an exogenous carrier and/or excipient. Also provided is a composition including a mixture of three acids, namely corosolic acid, oleanolic acid, and ursolic acid, which can be found in the Tecoma species. Methods of treating skin lesions (e.g. warts, corns, calluses, and umbilical granulomas) and reducing symptoms associated with the skin lesions using such compositions are specified.
    Type: Application
    Filed: September 4, 2019
    Publication date: March 19, 2020
    Applicants: National Guard Health Affairs, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center
    Inventor: Ayman Mahmoud SALEH
  • Publication number: 20100003675
    Abstract: The invention relates to a method for determining mastitis resistance in bovine subjects, wherein mastitis resistance comprise resistance to both sub-clinical and clinical mastitis. In particular, the method of the invention involves identification of genetic markers and/or Quantitative Trait Locus (QTL) for the determination of mastitis resistance in a bovine subject. The determination of mastitis resistance involves resolution of the specific microsatellite status. Furthermore, the invention relates to a diagnostic kit for detection of genetic marker(s) associated with mastitis resistance. The method and kit of the present invention can be applied for selection of bovine subjects for breeding purposes. Thus, the invention provides a method of genetically selecting bovine subjects with mastitis resistance, thereby yielding cows less prone to mastitis.
    Type: Application
    Filed: February 5, 2007
    Publication date: January 7, 2010
    Applicants: MTT Agrifood Research Finland, Aarhus Universitet, Estonian University of Life Sciences
    Inventors: Mogens Sando Lund, Bente Flugel Majgren, Goutam Sahana, Ayman Mahmoud Sabry, Peter Sorensen, Soren Svendsen, Bo Thomsen, Ingrid Lena Anderson-Eklund, Helmi Johanna Vilkki, Christian Bendixen, Terhi Katariina Iso-Touru, Sirja Maria Viitala, Nina Frederika Schulman, Nicola Hastings, John Lewis William Williams, John Arthur Woolliams, Ana Isabel Fernandez Avila, Haldja Viinalass, Sirje Varv