Patents by Inventor Ayman Mahmoud
Ayman Mahmoud has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11903987Abstract: A plant-based composition containing an alcohol extract of Tecoma species (e.g. Tecoma stans) and an exogenous carrier and/or excipient. Also provided is a composition including a mixture of three acids, namely corosolic acid, oleanolic acid, and ursolic acid, which can be found in the Tecoma species. Methods of treating skin lesions (e.g. warts, corns, calluses, and umbilical granulomas) and reducing symptoms associated with the skin lesions using such compositions are specified.Type: GrantFiled: May 7, 2021Date of Patent: February 20, 2024Assignees: National Guard Health Affairs, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research CenterInventor: Ayman Mahmoud Saleh
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Patent number: 11879000Abstract: A method for isolating a protein complex comprising BCL10 and at least one, preferably all, of ROS1, LSD1, BTK, KU80, KU70, CUL4A, IMP3, thioredoxin, hTID1, DAP3, CDK1/CDC2, PRL1/PTP4A1 or NM23. Methods for using this complex to diagnose or prognose diseases including diabetes, obesity, cancer, neurodegenerative disease or inflammatory diseases associated with activation of NF-?B. Methods for distinguishing lean, obese and diabetic subjects based on expression of BCL10 and its ligands are also disclosed. The invention also pertains to pharmaceutical compositions comprising ligands for BCL10 or other components of this complex or agents such as siRNA or miRNA that regulate the expression of the protein components of this complex.Type: GrantFiled: November 15, 2019Date of Patent: January 23, 2024Assignees: National Guard Health Affairs, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz City for Science and TechnologyInventors: Ayman Mahmoud Saleh, Mamoun Ahmad Salim Ahram, Amre Osman Nasr
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Publication number: 20230332804Abstract: A building heating and cooling system includes a structural foundation member that extends into a borehole. A heat exchange loop is installed within the foundation member for heat exchange with ground surrounding the foundation member. The heat exchange hoop is interconnected with a heat pump for providing heating or cooling to the building by heat exchange with ground surrounding the foundation member.Type: ApplicationFiled: September 14, 2021Publication date: October 19, 2023Inventors: Seyed Masih Alavy GHAHFARROKHY, Ladislav RAK, Jun WANG, David Ernest SALT, Afroozalsadat ALAVI, Jaroslava Marie-Magdalena PARSLOW, Seth B. DWORKIN, Ayman Mahmoud Bayomy MAHMOUD, Aggrey MWEISGYE, Hiep V. NGUYEN
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Patent number: 11455808Abstract: The invention relates to a method for the classification of parking spaces in a surrounding region of a vehicle with a driver support system, wherein the vehicle comprises at least one first surroundings sensor and a second surroundings sensor, comprising the steps of receiving first sensor data out of the surrounding region by the driver support system from the at least one first surroundings sensor, recognizing a parking-space-like partial region of the surrounding region in the first sensor data, requesting second sensor data acquired by the at least one second surroundings sensor out of the parking-space-like partial region by the driver support system as soon as the parking-space-like partial region is recognized in the first sensor data, transmitting the requested second sensor data to a vehicle-side computing unit comprising a deep neural network (DNN), and classifying the parking-space-like partial region into categories with the DNN, wherein the categories comprise legal, parkable parking spaces andType: GrantFiled: December 6, 2018Date of Patent: September 27, 2022Assignee: Valeo Schalter und Sensoren GmbHInventors: Malte Joos, Mathieu Bulliot, Mahmoud Shalaby, Ayman Mahmoud, Jean-Francois Bariant
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Publication number: 20210290714Abstract: A plant-based composition containing an alcohol extract of Tecoma species (e.g. Tecoma stans) and an exogenous carrier and/or excipient. Also provided is a composition including a mixture of three acids, namely corosolic acid, oleanolic acid, and ursolic acid, which can be found in the Tecoma species. Methods of treating skin lesions (e.g. warts, corns, calluses, and umbilical granulomas) and reducing symptoms associated with the skin lesions using such compositions are specified.Type: ApplicationFiled: May 7, 2021Publication date: September 23, 2021Applicants: National Guard Health Affairs, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research CenterInventor: Ayman Mahmoud SALEH
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Patent number: 11124499Abstract: A pharmaceutical composition containing an anti-proliferative compound, named Tecomaphorbide, which is identified and isolated from Tecoma plants (e.g. Tecoma stans). The pharmaceutical composition may contain a derivative and/or a salt of Tecomaphorbide. A process of obtaining Tecomaphorbide from Tecoma plants is specified. A method of treating cancer (e.g. leukemia, lymphoma, breast, colon, and prostate cancer) with the pharmaceutical composition is also provided.Type: GrantFiled: September 13, 2019Date of Patent: September 21, 2021Assignees: National Guard Health Affairs, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research CenterInventor: Ayman Mahmoud Saleh
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Patent number: 11090347Abstract: A plant-based composition containing an alcohol extract of Tecoma species (e.g. Tecoma stans) and an exogenous carrier and/or excipient. Also provided is a composition including a mixture of three acids, namely corosolic acid, oleanolic acid, and ursolic acid, which can be found in the Tecoma species. Methods of treating skin lesions (e.g. warts, corns, calluses, and umbilical granulomas) and reducing symptoms associated with the skin lesions using such compositions are specified.Type: GrantFiled: September 4, 2019Date of Patent: August 17, 2021Assignees: National Guard Health Affairs, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research CenterInventor: Ayman Mahmoud Saleh
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Publication number: 20210216797Abstract: The invention relates to a method for the classification of parking spaces in a surrounding region of a vehicle with a driver support system, wherein the vehicle comprises at least one first surroundings sensor and a second surroundings sensor, comprising the steps of receiving first sensor data out of the surrounding region by the driver support system from the at least one first surroundings sensor, recognizing a parking-space-like partial region of the surrounding region in the first sensor data, requesting second sensor data acquired by the at least one second surroundings sensor out of the parking-space-like partial region by the driver support system as soon as the parking-space-like partial region is recognized in the first sensor data, transmitting the requested second sensor data to a vehicle-side computing unit comprising a deep neural network (DNN), and classifying the parking-space-like partial region into categories with the DNN, wherein the categories comprise legal, parkable parking spaces andType: ApplicationFiled: December 6, 2018Publication date: July 15, 2021Applicant: Valeo Schalter und Sensoren GmbHInventors: Malte Joos, Mathieu Bulliot, Mahmoud Shalaby, Ayman Mahmoud
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Publication number: 20210148907Abstract: A method for isolated a protein complex comprising BCL10 and at least one, preferably all, of ROS1, LSD1, BTK, KU80, KU70, CUL4A, IMP3, thioredoxin, hTID1, DAP3, CDK1/CDC2, PRL1/PTP4A1 or NM23. Methods for using this complex to diagnose or prognose diseases including diabetes, obesity, cancer, neurodegenerative disease or inflammatory diseases associated with activation of NF-?B Methods for distinguishing lean, obese and diabetic subjects based on expression of BCL10 and its ligands are also disclosed. The invention also pertains to pharmaceutical compositions comprising ligands for BCL10 or other components of this complex or agents such as siRNA or miRNA that regulate the expression of the protein components of this complex.Type: ApplicationFiled: November 15, 2019Publication date: May 20, 2021Applicants: National Guard Health Affairs, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz City for Science and TechnologyInventors: Ayman Mahmoud Saleh, Mamoun Ahmad Salim Ahram, Amre Osman Nasr
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Publication number: 20200247786Abstract: A pharmaceutical composition containing an anti-proliferative compound, named Tecomaphorbide, which is identified and isolated from Tecoma plants (e.g. Tecoma stans). The pharmaceutical composition may contain a derivative and/or a salt of Tecomaphorbide. A process of obtaining Tecomaphorbide from Tecoma plants is specified. A method of treating cancer (e.g. leukemia, lymphoma, breast, colon, and prostate cancer) with the pharmaceutical composition is also provided.Type: ApplicationFiled: September 13, 2019Publication date: August 6, 2020Applicants: National Guard Health Affairs, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research CenterInventor: Ayman Mahmoud SALEH
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Publication number: 20200085894Abstract: A plant-based composition containing an alcohol extract of Tecoma species (e.g. Tecoma stans) and an exogenous carrier and/or excipient. Also provided is a composition including a mixture of three acids, namely corosolic acid, oleanolic acid, and ursolic acid, which can be found in the Tecoma species. Methods of treating skin lesions (e.g. warts, corns, calluses, and umbilical granulomas) and reducing symptoms associated with the skin lesions using such compositions are specified.Type: ApplicationFiled: September 4, 2019Publication date: March 19, 2020Applicants: National Guard Health Affairs, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research CenterInventor: Ayman Mahmoud SALEH
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Publication number: 20100003675Abstract: The invention relates to a method for determining mastitis resistance in bovine subjects, wherein mastitis resistance comprise resistance to both sub-clinical and clinical mastitis. In particular, the method of the invention involves identification of genetic markers and/or Quantitative Trait Locus (QTL) for the determination of mastitis resistance in a bovine subject. The determination of mastitis resistance involves resolution of the specific microsatellite status. Furthermore, the invention relates to a diagnostic kit for detection of genetic marker(s) associated with mastitis resistance. The method and kit of the present invention can be applied for selection of bovine subjects for breeding purposes. Thus, the invention provides a method of genetically selecting bovine subjects with mastitis resistance, thereby yielding cows less prone to mastitis.Type: ApplicationFiled: February 5, 2007Publication date: January 7, 2010Applicants: MTT Agrifood Research Finland, Aarhus Universitet, Estonian University of Life SciencesInventors: Mogens Sando Lund, Bente Flugel Majgren, Goutam Sahana, Ayman Mahmoud Sabry, Peter Sorensen, Soren Svendsen, Bo Thomsen, Ingrid Lena Anderson-Eklund, Helmi Johanna Vilkki, Christian Bendixen, Terhi Katariina Iso-Touru, Sirja Maria Viitala, Nina Frederika Schulman, Nicola Hastings, John Lewis William Williams, John Arthur Woolliams, Ana Isabel Fernandez Avila, Haldja Viinalass, Sirje Varv