Patent number: 10532984
Abstract: A pyridonecarboxylic acid derivative or a salt thereof is represented by Formula (1), where R1 is hydrogen, a halogen atom, a lower alkyl group, or an amino group; R2 is —NH—R6, where R6 is hydrogen, a lower alkyl group, an amino lower alkyl group, or the like; —O—R7, where R7 is hydrogen, a lower alkyl group, or the like; —(CH2)m—R8, where R8 is an amino group or the like, m is 1, 2, 3 or 4; or a cyclic amino group of Formula (2), where Y represents NH or C—R9aR9b, where R9a and R9b are each independently hydrogen, a lower alkyl group, an amino group, a lower alkyl amino group, or the like; n and p are 1 or 2; R3 is hydrogen, a halogen atom, a lower alkyl group, or the like; R4 is hydrogen or a carboxyl group-protecting group; and R5 is hydrogen or a hydroxyl group-protecting group.
Type:
Grant
Filed:
June 14, 2017
Date of Patent:
January 14, 2020
Assignee:
WAKUNAGA PHARMACEUTICAL CO., LTD.
Inventors:
Tomohiko Kinoshita, Yasuhiro Kuramoto, Satoshi Inoue, Kouji Nishimura, Tatsuya Hirano, Mai Arai, Asuka Sakurai, Daichi Kazamori, Ayuka Sasaki
Publication number: 20190276407
Abstract: A pyridonecarboxylic acid derivative or a salt thereof is represented by Formula (1), where R1 is hydrogen, a halogen atom, a lower alkyl group, or an amino group; R2 is —NH—R6, where R6 is hydrogen, a lower alkyl group, an amino lower alkyl group, or the like; —O—R7, where R7 is hydrogen, a lower alkyl group, or the like; —(CH2)m—R8, where R8 is an amino group or the like, m is 1, 2, 3 or 4; or a cyclic amino group of Formula (2), where Y represents NH or C—R9aR9b, where R9a and R9b are each independently hydrogen, a lower alkyl group, an amino group, a lower alkyl amino group, or the like; n and p are 1 or 2; R3 is hydrogen, a halogen atom, a lower alkyl group, or the like; R4 is hydrogen or a carboxyl group-protecting group; and R5 is hydrogen or a hydroxyl group-protecting group.
Type:
Application
Filed:
June 14, 2017
Publication date:
September 12, 2019
Applicant:
WAKUNAGA PHARMACEUTICAL CO., LTD.
Inventors:
Tomohiko KINOSHITA, Yasuhiro KURAMOTO, Satoshi INOUE, Kouji NISHIMURA, Tatsuya HIRANO, Mai ARAI, Asuka SAKURAI, Daichi KAZAMORI, Ayuka SASAKI