Abstract: A method for manufacturing a fan-in-fan-out device which does not require processing of a small-diameter hole and improves work efficiency of installation of an optical fiber, includes: arranging a first holding member in a hole of a second holding member, the hole being larger than an outer diameter of the first holding member, and holding a plurality of optical fibers between the first holding member and the second holding member respectively along a plurality of grooves formed on an outer periphery of the first holding member or an inner periphery of the hole of the second holding member; heating and integrally melting the arranged first holding member, the plurality of held optical fibers, and the second holding member in a portion including an axial end portion of the second holding member; and drawing the melted portion.

Abstract: A method for manufacturing a fan-in-fan-out device which does not require processing of a small-diameter hole and improves work efficiency of installation of an optical fiber, includes: arranging a first holding member in a hole of a second holding member, the hole being larger than an outer diameter of the first holding member, and holding a plurality of optical fibers between the first holding member and the second holding member respectively along a plurality of grooves formed on an outer periphery of the first holding member or an inner periphery of the hole of the second holding member; heating and integrally melting the arranged first holding member, the plurality of held optical fibers, and the second holding member in a portion including an axial end portion of the second holding member; and drawing the melted portion.

Abstract: There is provided a process for producing an optically active N-substituted azetidine-2-carboxylic acid compound represented by the formula (2): ##STR1## by contacting a corresponding N-substituted azetidine-2-carboxylic acid ester of formula (2) with an enzyme derived from a microorganism selected from Arthrobacter SC-6-98-28 strain, Arthrobacter sp. ATCC21908 strain, Chromobacterium SC-YM-1 strain, and a mutant thereof. A process is also provided for preparing an optically active azetidine-2-carboxylic acid by eliminating the N-substituent of a N-substituted azetidine-2-carboxylic acid ester of formula (2).