Patents by Inventor Ayumi Natsume

Ayumi Natsume has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for synthesizing sugar chains using ?1,3-N-acetylglucosaminyltransferase
    Patent number: 8722366
    Abstract: The present invention provides a novel polypeptide having a ?1,3-N-acetylglucosaminyltransferase activity; a method for producing the polypeptide; a DNA which encodes the polypeptide; a recombinant vector into which the DNA is inserted; a transformant comprising the recombinant vector; a method for producing a sugar chain or complex carbohydrate, using the polypeptide; a method for producing a sugar chain or complex carbohydrate, using the transformant; an antibody which recognizes the polypeptide; a method for screening a substance which changes the expression of the gene which encodes the polypeptide; and a method for screening a substance which changes the activity of the polypeptide.
    Type: Grant
    Filed: June 21, 2011
    Date of Patent: May 13, 2014
    Assignee: Kyowa Hakko Kirin Co., Ltd.
    Inventors: Katsutoshi Sasaki, Norihiko Shiraishi, Ayumi Natsume, Yoji Yamada, Satoshi Nakagawa, Susumu Sekine
  • USEFUL POLYPEPTIDES
    Publication number: 20120156732
    Abstract: The present invention provides a novel polypeptide having a ?1,3-N-acetylglucosaminyltransferase activity; a method for producing the polypeptide; a DNA which encodes the polypeptide; a recombinant vector into which the DNA is inserted; a transformant comprising the recombinant vector; a method for producing a sugar chain or complex carbohydrate, using the polypeptide; a method for producing a sugar chain or complex carbohydrate, using the transformant; an antibody which recognizes the polypeptide; a method for screening a substance which changes the expression of the gene which encodes the polypeptide; and a method for screening a substance which changes the activity of the polypeptide.
    Type: Application
    Filed: June 21, 2011
    Publication date: June 21, 2012
    Applicant: KYOWA HAKKO KIRIN CO., LTD.
    Inventors: Katsutoshi Sasaki, Norihiko Shiraishi, Ayumi Natsume, Yoji Yamada, Satoshi Nakagawa, Susumu Sekine
  • Method of producing sugar chain using human G4 polypeptide
    Patent number: 7972815
    Abstract: The present invention provides a novel polypeptide having a ?1,3-N-acetylglucosaminyl transferase activity; a method for producing the polypeptide; a DNA which encodes the polypeptide; a recombinant vector into which the DNA is inserted; a transformant comprising the recombinant vector; a method for producing a sugar chain or complex carbohydrate, using the polypeptide; a method for producing a sugar chain or complex carbohydrate, using the transformant; an antibody which recognizes the polypeptide; a method for screening a substance which changes the expression of the gene which encodes the polypeptide; and a method for screening a substance which changes the activity of the polypeptide.
    Type: Grant
    Filed: January 25, 2008
    Date of Patent: July 5, 2011
    Assignee: Kyowa Hakko Kirin Co., Ltd.
    Inventors: Katsutoshi Sasaki, Norihiko Shiraishi, Ayumi Natsume, Yoji Yamada, Satoshi Nakagawa, Susume Sekine
  • Transformed cell harboring DNA or RNA encoding sugar chain synthesizing agent having ?1,3-N-acetylglucosaminyltransferase activity
    Patent number: 7629150
    Abstract: The present invention provides a novel polypeptide having a ?1,3-N-acetylglucosaminyltransferase activity, an agent for synthesizing a sugar chain comprising the polypeptide, a process for producing a sugar chain or a complex carbohydrate using the agent for synthesizing a sugar chain, DNA encoding the polypeptide, a process for producing the polypeptide, an antibody against the polypeptide, and a diagnosis method and a medicament for treatment for inflammation, cancer or tumor metastasis using the DNA or the antibody. The present invention is useful for synthesis of a useful sugar chain and diagnosis and treatment for inflammatory diseases, cancer or tumor metastasis.
    Type: Grant
    Filed: August 13, 2007
    Date of Patent: December 8, 2009
    Assignees: Kyowa Hakko Kirin Co., Ltd.
    Inventors: Hisashi Narimatsu, Katsutoshi Sasaki, Ayumi Natsume, Hiroyuki Mio, Satoshi Nakagawa, Susumu Sekine, Akira Togayachi
  • USEFUL POLYPEPTIDES
    Publication number: 20090068720
    Abstract: The present invention provides a novel polypeptide having a ?1,3-N-acetylglucosaminyl transferase activity; a method for producing the polypeptide; a DNA which encodes the polypeptide; a recombinant vector into which the DNA is inserted; a transformant comprising the recombinant vector; a method for producing a sugar chain or complex carbohydrate, using the polypeptide; a method for producing a sugar chain or complex carbohydrate, using the transformant; an antibody which recognizes the polypeptide; a method for screening a substance which changes the expression of the gene which encodes the polypeptide; and a method for screening a substance which changes the activity of the polypeptide.
    Type: Application
    Filed: January 25, 2008
    Publication date: March 12, 2009
    Applicant: KYOWA HAKKO KOGYO CO., LTD.
    Inventors: Katsutoshi Sasaki, Norihiko Shiraishi, Ayumi Natsume, Yoji Yamada, Satoshi Nakagawa, Susumu Sekine
  • Sugar chain synthesizing agent having beta1,3-N-acetyglucosaminyltransferase activity
    Publication number: 20080050745
    Abstract: The present invention provides a novel polypeptide having a ?1,3-N-acetylglucosaminyltransferase activity, an agent for synthesizing a sugar chain comprising the polypeptide, a process for producing a sugar chain or a complex carbohydrate using the agent for synthesizing a sugar chain, DNA encoding the polypeptide, a process for producing the polypeptide, an antibody against the polypeptide, and a diagnosis method and a medicament for treatment for inflammation, cancer or tumor metastasis using the DNA or the antibody. The present invention is useful for synthesis of a useful sugar chain and diagnosis and treatment for inflammatory diseases, cancer or tumor metastasis.
    Type: Application
    Filed: August 13, 2007
    Publication date: February 28, 2008
    Applicant: KYOWA HAKKO KOGYO CO., LTD.
    Inventors: Hisashi Narimatsu, Katsutoshi Sasaki, Ayumi Natsume, Hiroyuki Mio, Satoshi Nakagawa, Susumu Sekine, Akira Togayachi
  • Process for producing sugar chains using ?1,3-N-acetylglucosaminyltransferase
    Patent number: 7279310
    Abstract: The present invention provides a novel polypeptide having a ?1,3-N-acetylglucosaminyltransferase activity, an agent for synthesizing a sugar chain comprising the polypeptide, a process for producing a sugar chain or a complex carbohydrate using the agent for synthesizing a sugar chain, DNA encoding the polypeptide, a process for producing the polypeptide, an antibody against the polypeptide, and a diagnosis method and a medicament for treatment for inflammation, cancer or tumor metastasis using the DNA or the antibody. The present invention is useful for synthesis of a useful sugar chain and diagnosis and treatment for inflammatory diseases, cancer or tumor metastasis.
    Type: Grant
    Filed: August 31, 2001
    Date of Patent: October 9, 2007
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Hisashi Narimatsu, Katsutoshi Sasaki, Ayumi Natsume, Hiroyuki Mio, Satoshi Nakagawa, Susumu Sekine, Akira Togayachi
  • Process for producing carbohydrates using ? 1,3-N-acetyl-glucosaminyltransferase
    Patent number: 7005279
    Abstract: The present invention provides a novel polypeptide having a ?1,3-N-acetylglucosaminyltransferase activity; a method for producing the polypeptide; a DNA which encodes the polypeptide; a recombinant vector into which the DNA is inserted; a transformant comprising the recombinant vector; a method for producing a sugar chain or complex carbohydrate, using the polypeptide; a method for producing a sugar chain or complex carbohydrate, using the transformant; an antibody which recognizes the polypeptide; a method for screening a substance which changes the expression of the gene which encodes the polypeptide; and a method for screening a substance which changes the activity of the polypeptide.
    Type: Grant
    Filed: June 29, 2000
    Date of Patent: February 28, 2006
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Katsutoshi Sasaki, Norihiko Shiraishi, Ayumi Natsume, Yoji Yamada, Satoshi Nakagawa, Susumu Sekine
  • Useful polypeptides
    Publication number: 20060030001
    Abstract: The present invention provides a novel polypeptide having a ?1,3-N-acetylglucosaminyltransferase activity; a method for producing the polypeptide; a DNA which encodes the polypeptide; a recombinant vector into which the DNA is inserted; a transformant comprising the recombinant vector; a method for producing a sugar chain or complex carbohydrate, using the polypeptide; a method for producing a sugar chain or complex carbohydrate, using the transformant; an antibody which recognizes the polypeptide; a method for screening a substance which changes the expression of the gene which encodes the polypeptide; and a method for screening a substance which changes the activity of the polypeptide.
    Type: Application
    Filed: June 9, 2005
    Publication date: February 9, 2006
    Applicant: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Katsutoshi Sasaki, Norihiko Shiraishi, Ayumi Natsume, Yoji Yamada, Satoshi Nakagawa, Susume Sekine
  • Novel polypeptide
    Publication number: 20040115763
    Abstract: The present invention provides a novel polypeptide having a &bgr;1,3-N-acetylglucosaminyltransferase activity, an agent for synthesizing a sugar chain comprising the polypeptide, a process for producing a sugar chain or a complex carbohydrate using the agent for synthesizing a sugar chain, DNA encoding the polypeptide, a process for producing the polypeptide, an antibody against the polypeptide, and a diagnosis method and a medicament for treatment for inflammation, cancer or tumor metastasis using the DNA or the antibody. The present invention is useful for synthesis of a useful sugar chain and diagnosis and treatment for inflammatory diseases, cancer or tumor metastasis.
    Type: Application
    Filed: September 12, 2003
    Publication date: June 17, 2004
    Inventors: Hisashi Narimatsu, Katsutoshi Sasaki, Ayumi Natsume, Hiroyuki Mio, Satoshi Nakagawa, Susumu Sekine, Akira Togayachi