Patents by Inventor Ayush Kishore

Ayush Kishore has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anticancer treatment for uveal melanoma
    Patent number: 11679113
    Abstract: Provided herein are methods for treating uveal melanoma in a subject in need thereof by administering an effective amount of an agent that inhibits expression of FAK protein to the subject. In one aspect, the agent that inhibits expression of FAK protein comprises, or alternatively consists essentially of, or yet further consists of a gene editing agent, such as for example one or more of: RNA interference (RNAi), CRISPR/Cas, ZFN, and/or TALEN. In another aspect, the agent is VS-4718. Also described herein are kits comprising, or alternatively consisting essentially of, or yet further consisting of one or more of: agents that inhibit expression of FAK protein, siRNAs, shRNAs, miRNAs, nucleases and/or guide RNA sequences for carrying out the methods of this disclosure, and optional instructions for use.
    Type: Grant
    Filed: March 19, 2020
    Date of Patent: June 20, 2023
    Assignee: The Regents of the University of California
    Inventors: Jorge Gutkind, David Schlaepfer, Justine Paradis, Ayush Kishore, Monica Acosta, Nadia Arang
  • ANTICANCER TREATMENT FOR UVEAL MELANOMA
    Publication number: 20200323863
    Abstract: Provided herein are methods for treating uveal melanoma in a subject in need thereof by administering an effective amount of an agent that inhibits expression of FAK protein to the subject. In one aspect, the agent that inhibits expression of FAK protein comprises, or alternatively consists essentially of, or yet further consists of a gene editing agent, such as for example one or more of: RNA interference (RNAi), CRISPR/Cas, ZFN, and/or TALEN. In another aspect, the agent is VS-4718. Also described herein are kits comprising, or alternatively consisting essentially of, or yet further consisting of one or more of: agents that inhibit expression of FAK protein, siRNAs, shRNAs, miRNAs, nucleases and/or guide RNA sequences for carrying out the methods of this disclosure, and optional instructions for use.
    Type: Application
    Filed: March 19, 2020
    Publication date: October 15, 2020
    Inventors: Jorge Gutkind, David Schlaepfer, Justine Paradis, Ayush Kishore, Monica Acosta, Nadia Arang