Patents by Inventor Azita Soltani
Azita Soltani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8192363Abstract: A catheter system for delivering ultrasonic energy to a treatment site includes a tubular body having a proximal end, a distal end and a treatment zone located between the distal end and the proximal end. An ultrasonic assembly is positioned within the treatment zone and provides providing an average longitudinal power density between about 0.2 and about 1.0 W/cm within the treatment zone.Type: GrantFiled: October 25, 2007Date of Patent: June 5, 2012Assignee: EKOS CorporationInventors: Azita Soltani, Robert L. Wilcox
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Patent number: 8192391Abstract: An ultrasound catheter system and a method for operating an ultrasonic catheter at a treatment site within a patient's vasculature or tissue are disclosed. The method of operating an ultrasonic catheter comprises advancing a catheter with at least one ultrasonic element to a treatment site in a patient's vascular system or tissue, driving the at least one ultrasonic element to generate ultrasonic energy, delivering a therapeutic compound to the treatment site through the catheter, and varying a power parameter and a physiological parameter of the ultrasonic element by ramping the power parameter and the physiological parameter between two set of minimum and maximum values.Type: GrantFiled: July 2, 2010Date of Patent: June 5, 2012Assignee: Ekos CorporationInventors: Azita Soltani, Kim R. Volz
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Publication number: 20120059285Abstract: An ultrasound catheter with a lumen for fluid delivery and fluid evacuation, and an ultrasound source is used for the treatment of intracerebral or intraventricular hemorrhages. After the catheter is inserted into a blood clot, a lytic drug can be delivered to the blood clot via the lumen while applying ultrasonic energy to the treatment site. As the blood clot is dissolved, the liquefied blood clot can be removed by evacuation through the lumen.Type: ApplicationFiled: August 26, 2011Publication date: March 8, 2012Applicant: EKOS CORPORATIONInventors: Azita Soltani, Raymond M. Wolniewcz, III, Brenton Nistal, Curtis Genstler, Robert L. Wilcox, Ronald L. Haas
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Publication number: 20110264031Abstract: In one embodiment of the present invention, a system for treating an occlusion within a patient's vasculature with ultrasonic energy comprises a catheter configured to be passed through the patient's vasculature such that a portion of the catheter is positioned at an intravascular treatment site. The system further comprises an ultrasound radiating member, an ultrasound signal generator configured to supply a drive signal to the ultrasound radiating member, an infusion pump configured to pump a therapeutic compound into the fluid delivery lumen so as to cause the therapeutic compound to be delivered to the treatment site and a controller configured to control the ultrasound signal generator and the infusion pump.Type: ApplicationFiled: July 5, 2011Publication date: October 27, 2011Applicant: EKOS CORPORATIONInventors: Azita Soltani, Adrian F. Prokop
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Publication number: 20110201974Abstract: In one embodiment of the present invention, a method of treating a vascular occlusion located at a treatment site within a patient's vasculature comprises positioning an ultrasound catheter at the treatment site. The method further comprises delivering a microbubble-therapeutic compound from the ultrasound catheter to the vascular occlusion during a first treatment phase.Type: ApplicationFiled: February 17, 2011Publication date: August 18, 2011Applicant: EKOS CORPORATIONInventors: Azita Soltani, Douglas R. Hansmann
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Publication number: 20110004105Abstract: An ultrasound catheter system and a method for operating an ultrasonic catheter at a treatment site within a patient's vasculature or tissue are disclosed. The ultrasound catheter system comprises a catheter having at least one ultrasonic element and a control system configured to generate power parameters that drive the at least one ultrasonic element to generate ultrasonic energy. The control system is configured to vary at least one of the power parameters and at least one physiological parameter by ramping the power parameter and the physiological parameter between two set of minimum and maximum values.Type: ApplicationFiled: July 2, 2010Publication date: January 6, 2011Applicant: EKOS CORPORATIONInventors: Azita Soltani, Kim R. Volz
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Publication number: 20100081934Abstract: In one embodiment of the present invention, a method of treating a vascular occlusion located at a treatment site within a patient's vasculature comprises positioning an ultrasound catheter at the treatment site. The method further comprises delivering a microbubble therapeutic compound from the ultrasound catheter to the vascular occlusion during a first treatment phase. The method further comprises pausing the delivery of the microbubble therapeutic compound and delivering ultrasonic energy from the ultrasound catheter to the vascular occlusion during a second treatment phase while the delivery of microbubble therapeutic compound remains paused.Type: ApplicationFiled: December 2, 2009Publication date: April 1, 2010Applicant: EKOS CORPORATIONInventors: Azita Soltani, Douglas R. Hansmann
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Patent number: 7648478Abstract: In one embodiment of the present invention, a method of treating a vascular occlusion located at a treatment site within a patient's vasculature comprises positioning an ultrasound catheter at the treatment site. The method further comprises delivering a microbubble therapeutic compound from the ultrasound catheter to the vascular occlusion during a first treatment phase. The method further comprises pausing the delivery of the microbubble therapeutic compound and delivering ultrasonic energy from the ultrasound catheter to the vascular occlusion during a second treatment phase while the delivery of microbubble therapeutic compound remains paused.Type: GrantFiled: March 11, 2008Date of Patent: January 19, 2010Assignee: Ekos CorporationInventors: Azita Soltani, Douglas R. Hansmann
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Publication number: 20090187137Abstract: In one embodiment of the present invention, an ultrasound catheter system comprising a catheter having at least one ultrasonic element; and a control system configured to generate power parameters to drive the ultrasonic element to generate ultrasonic energy is provided. The control system is configured to provide an ultrasonic pulse with a high pressure gradient with respect to time and/or distance. In another embodiment, a method of enhancing delivery of a therapeutic compound comprising delivering the therapeutic compound to a treatment site in a patient; and exposing the treatment site to an ultrasonic energy generated by an oscillating electrical signal pattern having a rise or fall rate greater than an sinusoidal pattern for the same amplitude and frequency is provided.Type: ApplicationFiled: December 12, 2008Publication date: July 23, 2009Inventors: KIM VOLZ, Azita Soltani
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Publication number: 20090018472Abstract: In one embodiment of the present invention, a method of applying ultrasonic energy to a treatment site within a patient's vasculature comprises positioning an ultrasound radiating member at a treatment site within a patient's vasculature. The method further comprises activating the ultrasound radiating member to produce pulses of ultrasonic energy at a cycle period T?1 second. The acoustic parameters such as peak power, pulse width, pulse repetition frequency and frequency or any combination of them can be varied non-linearly.Type: ApplicationFiled: July 9, 2008Publication date: January 15, 2009Inventors: Azita Soltani, Kim R. Volz
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Publication number: 20080208109Abstract: In one embodiment of the present invention, a method of treating a vascular occlusion located at a treatment site within a patient's vasculature comprises positioning an ultrasound catheter at the treatment site. The method further comprises delivering a microbubble therapeutic compound from the ultrasound catheter to the vascular occlusion during a first treatment phase. The method further comprises pausing the delivery of the microbubble therapeutic compound and delivering ultrasonic energy from the ultrasound catheter to the vascular occlusion during a second treatment phase while the delivery of microbubble therapeutic compound remains paused.Type: ApplicationFiled: March 11, 2008Publication date: August 28, 2008Applicant: Ekos CorporationInventors: Azita Soltani, Douglas R. Hansmann
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Publication number: 20080171965Abstract: In one embodiment of the present invention, a method of applying ultrasonic energy to a treatment site within a patient's vasculature comprises positioning an ultrasound radiating member at a treatment site within a patient's vasculature. The method further comprises activating the ultrasound radiating member to produce pulses of ultrasonic energy at a cycle period T?1 second. The acoustic parameters such as peak power, pulse width, pulse repetition frequency and frequency or any combination of them can be varied non-linearly.Type: ApplicationFiled: January 8, 2008Publication date: July 17, 2008Applicant: EKOS CORPORATIONInventors: Azita Soltani, Kim R. Volz
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Publication number: 20080103417Abstract: A catheter system for delivering ultrasonic energy to a treatment site includes a tubular body having a proximal end, a distal end and a treatment zone located between the distal end and the proximal end. An ultrasonic assembly is positioned within the treatment zone and provides providing an average longitudinal power density between about 0.2 and about 1.0 W/cm within the treatment zone.Type: ApplicationFiled: October 25, 2007Publication date: May 1, 2008Inventors: Azita Soltani, Robert Wilcox
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Patent number: 7341569Abstract: In one embodiment of the present invention, a method of treating a vascular occlusion located at a treatment site within a patient's vasculature comprises positioning an ultrasound catheter at the treatment site. The method further comprises delivering a microbubble therapeutic compound from the ultrasound catheter to the vascular occlusion during a first treatment phase. The method further comprises pausing the delivery of the microbubble compound and delivering ultrasonic energy from the ultrasound catheter in combination with other therapeutic compounds to the vascular occlusion during a second treatment phase while the delivery of microbubble therapeutic compound remains paused.Type: GrantFiled: January 28, 2005Date of Patent: March 11, 2008Assignee: EKOS CorporationInventors: Azita Soltani, Douglas R. Hansmann
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Publication number: 20070265560Abstract: In one embodiment of the present invention, a system for treating an occlusion within a patient's vasculature with ultrasonic energy comprises a catheter configured to be passed through the patient's vasculature such that a portion of the catheter is positioned at an intravascular treatment site. The system further comprises an ultrasound radiating member, an ultrasound signal generator configured to supply a drive signal to the ultrasound radiating member, an infusion pump configured to pump a therapeutic compound into the fluid delivery lumen so as to cause the therapeutic compound to be delivered to the treatment site and a controller configured to control the ultrasound signal generator and the infusion pump.Type: ApplicationFiled: April 24, 2007Publication date: November 15, 2007Applicant: EKOS CORPORATIONInventors: Azita Soltani, Adrian Prokop
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Publication number: 20060264809Abstract: In one embodiment of the present invention, a method of applying ultrasonic energy to a treatment site within a patient's vasculature comprises positioning an ultrasound radiating member at a treatment site within a patient's vasculature. The method further comprises activating the ultrasound radiating member to produce pulses of ultrasonic energy at a cycle period T?1 second. Each pulse of ultrasonic energy has a first peak amplitude for a first duration, and a second reduced amplitude that is less than the first peak amplitude for a second duration.Type: ApplicationFiled: April 12, 2006Publication date: November 23, 2006Inventors: Douglas Hansmann, Azita Soltani
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Publication number: 20050192556Abstract: In one embodiment of the present invention, a method of treating a vascular occlusion located at a treatment site within a patient's vasculature comprises positioning an ultrasound catheter at the treatment site. The method further comprises delivering a microbubble therapeutic compound from the ultrasound catheter to the vascular occlusion during a first treatment phase. The method further comprises pausing the delivery of the microbubble compound and delivering ultrasonic energy from the ultrasound catheter in combination with other therapeutic compounds to the vascular occlusion during a second treatment phase while the delivery of microbubble therapeutic compound remains paused.Type: ApplicationFiled: January 28, 2005Publication date: September 1, 2005Inventors: Azita Soltani, Douglas Hansmann