Patents by Inventor Béatrice Cameron

Béatrice Cameron has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified soluble FGF receptor Fc fusions with improved biological activity
    Patent number: 8119770
    Abstract: The invention relates to modified soluble FGF receptor Fc fusions comprising a fusion of a soluble fragment or domain of the FGF receptor part (targeting or binding moiety) with an Fc region of an immunoglobulin part (effector function moiety), having improved biological activity including ADCC/CDC activities, compositions containing them, and method of producing such modified soluble FGF receptor Fc fusion molecules.
    Type: Grant
    Filed: November 28, 2007
    Date of Patent: February 21, 2012
    Assignee: Aventis Pharma SA
    Inventors: Francis Blanche, Beatrice Cameron, Mark Nesbit, Sylvie Sordello, Celine Nicolazzi, Marc Trombe
  • PURIFICATION OF A TRIPLE HELIX FORMATION WITH AN IMMOBILIZED OLIGONUCLEOTIDE
    Publication number: 20110319605
    Abstract: Method for double-stranded DNA purification, by which a solution containing said DNA in a mixture with other components is passed over a support on which is covalently coupled in oligonucleotide capable of hybridizing with a specific sequence present on said DNA to form a triple helix.
    Type: Application
    Filed: August 8, 2011
    Publication date: December 29, 2011
    Applicant: Centelion
    Inventors: Joël CROUZET, Daniel Scherman, Pierre Wils, Françis Blanche, Béatrice Cameron
  • Purification of a triple helix formation with an immobilized oligonucleotide
    Patent number: 8017744
    Abstract: A method for double-stranded DNA purification, by which a solution containing DNA in a mixture with other components is passed over a support on which is covalently coupled an oligonucleotide capable of hybridizing with a specific sequence present on the DNA to form a triple helix.
    Type: Grant
    Filed: June 4, 2009
    Date of Patent: September 13, 2011
    Assignee: Centelion
    Inventors: Joël Crouzet, Daniel Scherman, Pierre Wils, Françis Blanche, Béatrice Cameron
  • FGF-R4 RECEPTOR-SPECIFIC ANTAGONISTS
    Publication number: 20110150903
    Abstract: The present invention relates to FGF-R4 receptor-specific antagonist molecules enabling the inhibition of the activity of said receptor. Said antagonists are, particularly, FGF-R4-specific antibodies enabling the inhibition of the activity of said receptor. The present invention also relates to the therapeutic use of said antibodies, particularly in the field of angiogenesis and in the treatment of certain types of cancer.
    Type: Application
    Filed: July 7, 2009
    Publication date: June 23, 2011
    Applicant: SANOFI-AVENTIS
    Inventors: Nicolas Baurin, Pierre-Francois Berne, Francis Blanche, Francoise Bono, Beatrice Cameron, Tarik Dabdoubi, Corentin Herbert, Vincent Mikol, Elisabeth Remy
  • Humanized anti-CXCR5 antibodies, derivatives thereof and their use
    Publication number: 20110027266
    Abstract: The present invention relates to humanized antibodies that specifically bind to CXCR5 and can, for example, inhibit CXCR5 function. The invention also includes uses of the antibodies to treat or prevent CXCR5 related diseases or disorders.
    Type: Application
    Filed: August 27, 2008
    Publication date: February 3, 2011
    Applicant: SANOFI-AVENTIS
    Inventors: Renata Lee, Vincent Mikol, Elizabeth Allen, Norman Ruetsch, Beatrice Cameron, Thomas Oligino, Nicolas Baurin
  • MODIFIED SOLUBLE FGF RECEPTOR FC FUSIONS WSITH IMPROVED BIOLOGICAL ACTIVITY
    Publication number: 20100061979
    Abstract: The invention relates to modified soluble FGF receptor Fc fusions comprising a fusion of a soluble fragment or domain of the FGF receptor part (targeting or binding moiety) with an Fc region of an immunoglobulin part (effector function moiety), having improved biological activity including ADCC/CDC activities, compositions containing them, and method of producing such modified soluble FGF receptor Fc fusion molecules.
    Type: Application
    Filed: November 22, 2007
    Publication date: March 11, 2010
    Applicant: CENTELION
    Inventors: Francis Blanche, Beatrice Cameron, Mark Nesbit, Sylvie Sordello, Celine Nicolazzi, Marc Trombe
  • PURIFICATION OF A TRIPLE HELIX FORMATION WITH AN IMMOBILIZED OLIGONUCLEOTIDE
    Publication number: 20100010208
    Abstract: Method for double-stranded DNA purification, by which a solution containing said DNA in a mixture with other components is passed over a support on which is covalently coupled in oligonucleotide capable of hybridizing with a specific sequence present on said DNA to form a triple helix.
    Type: Application
    Filed: June 4, 2009
    Publication date: January 14, 2010
    Applicant: Centelion
    Inventors: Joël CROUZET, Daniel Scherman, Pierre Wils, Françis Blanche, Béatrice Cameron
  • Processes for purifying and for detecting target double-stranded DNA sequences by triple helix interaction
    Patent number: 7514218
    Abstract: The present invention relates to novel target double-stranded DNA sequences capable of interacting with a third strand and of forming a stable triple helix. The present invention also relates to a process for purifying a double-stranded DNA molecule, according to which a solution containing said DNA molecule is brought into contact with a third DNA strand capable of forming, by hybridization, a triple helix structure with a target double-stranded DNA sequence carried by said DNA molecule.
    Type: Grant
    Filed: March 20, 2006
    Date of Patent: April 7, 2009
    Assignee: Centelion
    Inventors: Francis Blanche, Beatrice Cameron
  • Processes for purifying and for detecting target double-stranded DNA sequences by triple helix interaction
    Publication number: 20080064031
    Abstract: The present invention relates to novel target double-stranded DNA sequences capable of interacting with a third strand and of forming a stable triple helix. The present invention also relates to a process for purifying a double-stranded DNA molecule, according to which a solution containing said DNA molecule is brought into contact with a third DNA strand capable of forming, by hybridization, a triple helix structure with a target double-stranded DNA sequence carried by said DNA molecule.
    Type: Application
    Filed: March 20, 2006
    Publication date: March 13, 2008
    Inventors: Francis Blanche, Beatrice Cameron
  • Processes for purifying and for detecting target double-stranded DNA sequences by triple helix interaction
    Publication number: 20060205000
    Abstract: The present invention relates to novel target double-stranded DNA sequences capable of interacting with a third strand and of forming a stable triple helix. The present invention also relates to a process for purifying a double-stranded DNA molecule, according to which a solution containing said DNA molecule is brought into contact with a third DNA strand capable of forming, by hybridization, a triple helix structure with a target double-stranded DNA sequence carried by said DNA molecule.
    Type: Application
    Filed: March 20, 2006
    Publication date: September 14, 2006
    Inventors: Francis Blanche, Beatrice Cameron
  • Processes for purifying and for detecting target double-stranded DNA sequences by triple helix interaction
    Patent number: 7052838
    Abstract: The present invention relates to novel target double-stranded DNA sequences capable of interacting with a third strand and of forming a stable triple helix. The present invention also relates to a process for purifying a double-stranded DNA molecule, according to which a solution containing said DNA molecule is brought into contact with a third DNA strand capable of forming, by hybridization, a triple helix structure with a target double-stranded DNA sequence carried by said DNA molecule.
    Type: Grant
    Filed: March 25, 2002
    Date of Patent: May 30, 2006
    Assignee: Centelion
    Inventors: Francis Blanche, Béatrice Cameron
  • Purification of a triple heli formation with an immobilized oligonucleotide
    Patent number: 7038026
    Abstract: Method for double-stranded DNA purification, by which a solution containing said DNA in a mixture with other components is passed over a support on which is covalently coupled in oligonucleotide capable of hybridizing with a specific sequence present on said DNA to form a triple helix.
    Type: Grant
    Filed: May 25, 2001
    Date of Patent: May 2, 2006
    Assignee: Centelion
    Inventors: Joël Crouzet, Daniel Scherman, Pierre Wils, Françis Blanche, Béatrice Cameron
  • Purification of a triple helix formation with an immobilized oligonucleotide
    Publication number: 20060036085
    Abstract: Method for double-stranded DNA purification, by which a solution containing said DNA in a mixture with other components is passed over a support on which is covalently coupled in oligonucleotide capable of hybridizing with a specific sequence present on said DNA to form a triple helix.
    Type: Application
    Filed: October 20, 2005
    Publication date: February 16, 2006
    Applicant: Centelion
    Inventors: Joel Crouzet, Daniel Scherman, Pierre Wils, Francis Blanche, Beatrice Cameron
  • Methods of increasing the production of cobalamins using cob gene expression
    Publication number: 20060019352
    Abstract: Novel polypeptides involved in the biosynthesis of cobalamines and/or cobamides, in particular coenzyme B12, genetic material responsible for expressing these polypeptides, and a method for preparing them, are described. A method for amplifying the production of cobalamines, and particularly coenzyme B12, using recombinant DNA techniques, are also described.
    Type: Application
    Filed: December 1, 2003
    Publication date: January 26, 2006
    Inventors: Francis Blanche, Beatrice Cameron, Joel Crouzet, Laurent Debussche, Sophie Levy Schil, Denis Thibaut
  • DNA molecules, preparation and use in gene therapy
    Patent number: 6825012
    Abstract: The invention provides double-stranded circular DNA molecules having one or more genes of interest, but lacking an origin of replication and a selectable marker, and methods for making such molecules.
    Type: Grant
    Filed: October 19, 2001
    Date of Patent: November 30, 2004
    Assignee: Gencell S.A.
    Inventors: Francis Blanche, Béatrice Cameron
  • Novel topoisomerase IV, corresponding nucleotide sequences and uses thereof
    Publication number: 20040077005
    Abstract: The present invention generally relates to a novel topoisomerase IV, the nucleotide sequences encoding this enzyme, their corresponding vectors, and the use of this enzyme for screening biologically active products.
    Type: Application
    Filed: August 25, 2003
    Publication date: April 22, 2004
    Applicant: Aventis Pharma S.A.
    Inventors: Francis Blanche, Beatrice Cameron, Joel Crouzet, Alain Famechon, Lucia Ferrero
  • Abrogen polypeptides, nucleic acids encoding them and methods for using them to inhibit angiogenesis
    Publication number: 20040052810
    Abstract: The present invention relates to novel nucleic acids encoding novel amino acid fragments of polypeptides, called abrogens. The present invention also relates to novel, potent in vitro and in vivo inhibitors of endothelial cell proliferation, and compositions of them and their use. The present invention further provides methods for modulating angiogenesis and/or inhibiting unwanted angiogenesis. Polypeptides according to the present invention are useful for developing cell growth-modulating compositions and methods and for treating and/or preventing cancer, tumor growth, or other angiogenic dependent or angiogenesis associated diseases.
    Type: Application
    Filed: April 29, 2003
    Publication date: March 18, 2004
    Inventors: Mark Nesbit, Beatrice Cameron, Francis Blanche
  • Kringle polypeptides and methods for using them to inhibit angiogenesis
    Publication number: 20040052777
    Abstract: The present invention relates to kringle polypeptides and polynucleotides encoding kringle polypeptides and their use as therapeutic agents and in methods of identifying agonist compounds. In effect, the kringle polypeptides according to the present invention are particularly useful for inhibiting in vitro and in vivo proliferation, migration and/or invasion of endothelial cells, recruitment of smooth muscle cells, and/or the formation of vasculature in a tissue. The present invention also relates to the use of kringle polypeptides for treating and/or preventing angiogenesis in tumors and inhibiting the growth of tumors. The present invention further relates to a method of modulating angiogenesis in cells affected by an angiogenic-dependent process and inhibiting unwanted or unregulated angiogenesis in an angiogenesis-associated disease. The present invention also concerns a method of production and purification of kringle polypeptides in a soluble and active form.
    Type: Application
    Filed: April 29, 2003
    Publication date: March 18, 2004
    Inventors: Mark Nesbit, Beatrice Cameron, Francis Blanche
  • Methods of increasing the production of cobalamins using cob gene expression
    Patent number: 6656709
    Abstract: Novel polypeptides involved in the biosynthesis of cobalamines and/or cobamides, in particular coenzyme B12, genetic material responsible for expressing these polypeptides, and a method for preparing them, are described. A method for amplifying the production of cobalamines, and particularly coenzyme B12, using recombinant DNA techniques, are also described.
    Type: Grant
    Filed: April 21, 1995
    Date of Patent: December 2, 2003
    Assignee: Rhone-Poulenc Biochimie, et al.
    Inventors: Francis Blanche, Beatrice Cameron, Joel Crouzet, Laurent Debussche, Sophie Levy Schil, Denis Thibaut
  • Cells with altered betaine catabolism and their use in producing metabolites or enzymes
    Patent number: RE38331
    Abstract: Cells with an alteration at least in the gene involved in betaine catabolism, their preparation and their use, in particular for producing metabolites and/or enzymes, are disclosed.
    Type: Grant
    Filed: May 9, 2001
    Date of Patent: November 25, 2003
    Assignee: Rhone-Poulenc Biochimie
    Inventors: Beatrice Cameron, Joel Crouzet