Patents by Inventor B. Mark Evers

B. Mark Evers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of predicting obesity comprising measuring neurotensin
    Patent number: 10473670
    Abstract: The presently disclosed subject matter relates to a method for predicting increased risk of obesity on a non-obese subject. More particularly, the presently disclosed subject matter relates to a method of predicting increased risk of obesity in a non-obese subject by determining a level of neurotensin expression in a biological sample from the subject and comparing the level of neurotensin expression in the sample with a control level. The presently disclosed subject matter further relates to a method of preventing and/or treating obesity in a subject in need thereof by administering to the subject an effective amount of an agent that inhibits neurotensin.
    Type: Grant
    Filed: February 27, 2017
    Date of Patent: November 12, 2019
    Assignees: University of Kentucky Research Foundation, University of Massachusetts
    Inventors: B. Mark Evers, Jing Li, Paul Dobner, Olle Melander
  • METHOD OF PREDICTING OBESITY
    Publication number: 20170248610
    Abstract: The presently disclosed subject matter relates to a method for predicting increased risk of obesity on a non-obese subject. More particularly, the presently disclosed subject matter relates to a method of predicting increased risk of obesity in a non-obese subject by determining a level of neurotensin expression in a biological sample from the subject and comparing the level of neurotensin expression in the sample with a control level. The presently disclosed subject matter further relates to a method of preventing and/or treating obesity in a subject in need thereof by administering to the subject an effective amount of an agent that inhibits neurotensin.
    Type: Application
    Filed: February 27, 2017
    Publication date: August 31, 2017
    Inventors: B. Mark Evers, Jing Li, Paul Dobner, Olle Melander
  • SIRNA INHIBITION OF P13K P85, PA110, AND AKT2 AND METHODS OF USE
    Publication number: 20100035965
    Abstract: The present invention provides polynucleotides, compositions including polynucleotides, and the uses thereof for treating cancer in a subject. The polynucleotides silence the expression of coding regions that encode polypeptides such as p85?, p110?, and Akt2. The cancers treatable using the methods described herein include colorectal cancer, breast cancer, lung cancer, and metastases thereof.
    Type: Application
    Filed: May 18, 2007
    Publication date: February 11, 2010
    Inventors: B. Mark Evers, Piotr G. Rychahou