Abstract: Aspects relate to calculating energy expenditure values from an apparatus configured to be worn on an appendage of a user. Steps counts may be quantified, such as by detecting arm swings peaks and bounce peaks in motion data. A search range of acceleration frequencies related to an expected activity may be established. Frequencies of acceleration data within a search range may be analyzed to identify one or more peaks, such as a bounce peak and an arm swing peak. Novel systems and methods may determine whether to utilize the arm swing data, bounce data, and/or other data or portions of data to quantify steps. The number of peaks (and types of peaks) may be used to choose a step frequency and step magnitude. At least a portion of the motion data may be classified into an activity category based upon the quantification of steps.

Abstract: A prime mover is shown which can be used in supplying power for a variety of roles in industrial applications, including oil and gas well operations, such as the prime mover which is used to operate a pump jack at a well site. It includes an internal combustion engine having an output shaft, the engine being cooled by engine oil supplied from an oil reservoir to the engine and circulated by an oil pump. A housing framework encloses the engine and supports an associated jack shaft bearing assembly, and includes a base, a hood and a plurality of upright supports which extend upwardly from the base in the direction of the hood. One or more of the uprights is a specially designed compartment having a plurality of opposing sides which define an initially open interior space, the interior space comprising an integral oil reservoir for storing and supplying oil to the engine during normal engine operation.

Abstract: A proprotor blade (27a, 27b, 127a, 127b) having a fixed, spanwise, leading edge slot (215) located in at least the inboard portion of the proprotor is disclosed. The slot (215) is formed by a selectively shaped slat (217) disposed in a selectively shaped recessed area (219) located at the leading edge (202) of the main portion of the proprotor blade. The slot (215) is selectively shaped so the a portion of the airflow over the lower airfoil surface of the proprotor blade is diverted between the main portion of the proprotor blade and the slat (217) and exits at the upper airfoil surface of the proprotor blade. The present invention may be used on both military-type tiltrotor aircraft (11) and civilian-type tiltrotor aircraft (111) with only minor variations to accommodate the different shapes of the proprotor blades.

Abstract: A prime mover is shown which can be used in supplying power for a variety of roles in industrial applications, including oil and gas well operations, such as the prime mover which is used to operate a pump jack at a well site. It includes an internal combustion engine having an output shaft, the engine being cooled by engine oil supplied from an oil reservoir to the engine and circulated by an oil pump. A housing framework encloses the engine and supports an associated jack shaft bearing assembly, and includes a base, a hood and a plurality of upright supports which extend upwardly from the base in the direction of the hood. One or more of the uprights is a specially designed compartment having a plurality of opposing sides which define an initially open interior space, the interior space comprising an integral oil reservoir for storing and supplying oil to the engine during normal engine operation.

Abstract: A proprotor blade (27a, 27b, 127a, 127b) having a fixed, spanwise, leading edge slot (215) located in at least the inboard portion of the proprotor is disclosed. The slot (215) is formed by a selectively shaped slat (217) disposed in a selectively shaped recessed area (219) located at the leading edge (202) of the main portion of the proprotor blade. The slot (215) is selectively shaped so the a portion of the airflow over the lower airfoil surface of the proprotor blade is diverted between the main portion of the proprotor blade and the slat (217) and exits at the upper airfoil surface of the proprotor blade. The present invention may be used on both military-type tiltrotor aircraft (11) and civilian-type tiltrotor aircraft (111) with only minor variations to accommodate the different shapes of the proprotor blades.

Abstract: This invention is directed generally to proteinase (also known as “protease”) inhibitors, and, more particularly, to piperidinyl- and piperazinyl-sulfonylmethyl hydroxamic acids that, inter alia, inhibit matrix metalloproteinase (also known as “matrix metalloprotease” or “MMP”) activity and/or aggrecanase activity. Such hydroxamic acids generally correspond in structure to the following formula: (wherein A1, A2, Y, E1, E2, E3, and Rx are as defined in this specification), and further include salts of such compounds. This invention also is directed to compositions of such hydroxamic acids, intermediates for the syntheses of such hydroxamic acids, methods for making such hydroxamic acids, and methods for treating conditions (particularly pathological conditions) associated with MMP activity and/or aggrecanase activity.

Abstract: A treatment process is disclosed that comprises administering an effective amount of an aromatic sulfone hydroxamic acid that exhibits excellent inhibitory activity of one or more matrix metalloprotease (MMP) enzymes, such as MMP-2, MMP-9, and MMP-13, while exhibiting substantially less inhibition at least of MMP-1 to a host having a condition associated with pathological matrix metalloprotease activity. The administered enzyme inhibitor corresponds in structure to formula (I), below, or a pharmaceutically acceptable salt thereof, wherein R1 and R2 are both hydrido or R1 and R2 together with the atoms to which they are bonded form a 5- to 8-membered ring containing one, two, or three heteroatoms in the ring that are oxygen, sulfur, or nitrogen. R3 in formula (I) is an optionally substituted aryl or optionally substituted heteroaryl radical.

Abstract: A treatment process is disclosed that comprises administering an effective amount of an aromatic sulfone hydroxamic acid that exhibits excellent inhibitory activity of one or more matrix metalloprotease (MMP) enzymes, such as MMP-2, MMP-9, and MMP-13, while exhibiting substantially less inhibition at least of MMP-1 to a host having a condition associated with pathological matrix metalloprotease activity. The administered enzyme inhibitor corresponds in structure to formula (I), below, or a pharmaceutically acceptable salt thereof, wherein R1 and R2 are both hydrido or R1 and R2 together with the atoms to which they are bonded form a 5- to 8-membered ring containing one, two, or three heteroatoms in the ring that are oxygen, sulfur, or nitrogen. R3 in formula (I) is an optionally substituted aryl or optionally substituted heteroaryl radical.

Abstract: This invention is directed to aromatic sulfone hydroxamates (also known as “aromatic sulfone hydroxamic acids”) and salts thereof that, inter alia, inhibit matrix metalloproteinase (also known as “matrix metalloprotease” or “MMP”) activity and/or aggrecanase activity. This invention also is directed to a prevention or treatment method that comprises administering such a compound or salt in an MMP-inhibiting and/or aggrecanase-inhibiting effective amount to an animal, particularly a mammal having (or disposed to having) a pathological condition associated with MMP and/or aggrecanase activity.

Abstract: A system and method for regulating an adjustable DC supply and continuously and remotely monitoring measurements of reference cell potential and/or current for cathodic protection of a structure is disclosed. Cathodic protection devices use a logic circuit and/or microprocessor based monitor for removing identifiable components and noise from the system to arrive at the DC bias. A method is implemented herein to arrive at the true value of a reference cell potential measurement determined within a sample collection point or window calculated for the reference cell signal while the impressed current is still being applied. This measurement can be compared to a calculated shutdown and is communicated to a central computer accessible via a network such as the Internet. All output is automatically regulated and checked for target window accuracy using an automated voting scheme.

Abstract: A process and system for recovering fine coal having a size at or below 400 mesh. The process and system includes a series of cyclone separators, a vibrating screen, a centrifuge and a flow path to clean, recover and dewater fine coal having a nominal size of 3 mm down to 400 mesh or below. The process and system includes the use of commercially available components arranged in a novel manner to efficiently recover fine coal for use in various energy supplying systems.

Abstract: A process and system for recovering fine coal having a size at or below 400 mesh. The process and system includes a series of cyclone separators, vibratory separators, centrifuges and a flow path to clean, recover and dewater fine coal having a nominal size of 3 mm down to 400 mesh or below. The process and system includes the use of commercially available components arranged in a novel manner to efficiently recover fine coal for use in various energy supplying systems.

Abstract: An N-hydroxy sulfonyl butanamide compound that inter alia inhibits matrix metalloprotease activity is disclosed as are a treatment process that comprises administering a contemplated N-hydroxy sulfonyl butanamide compound in a MMP enzyme-inhibiting effective amount to a host having a condition associated with pathological matrix metalloprotease activity.

Abstract: A tracked GPS guided ground clearing apparatus and method for clearing brush, small trees, snow, ice and other types of debris, dependent upon remote positioning data and radio communication signals, having an apparatus locator system for determining the location of the apparatus and a guidance system for navigating and maintaining the apparatus in a desired direction of travel along a particular line of travel and for traversing a plurality of specific data points along the particular line of travel, relative to the surface of the earth.

Abstract: A system and method for regulating an adjustable DC supply and continuously and remotely monitoring measurements of reference cell potential and/or current for cathodic protection of a structure is disclosed. Cathodic protection devices use a logic circuit and/or microprocessor based monitor for removing identifiable components and noise from the system to arrive at the DC bias. A method is implemented herein to arrive at the true value of a reference cell potential measurement determined within a sample collection point or window calculated for the reference cell signal while the impressed current is still being applied. This measurement can be compared to a calculated shutdown and is communicated to a central computer accessible via a network such as the Internet. All output is automatically regulated and checked for target window accuracy using an automated voting scheme.

Abstract: A method and apparatus for navigating a remotely guided brush cutting, chipping and clearing apparatus, dependent upon remote positioning data and radio communication signals, having an apparatus locator system for determining the location of the apparatus and a guidance system for navigating and maintaining the apparatus in a desired direction of travel along a particular line of travel and for traversing a plurality of specific data points along the particular line of travel, relative to the surface of the earth.

Abstract: The invention provides devices and methods for suture placement while performing less invasive surgical procedures within a body cavity. In an exemplary embodiment, the invention provides for the placement of sutures within the heart or a great vessel that is accessed from outside the closed chest. According to one exemplary method, the patient's heart valve is accessed through an intercostal port in the patient's chest. At least one needle having a suture is then directed into the annulus while visualizing through the port placement of the needle into the annulus. The needle is then passed through the annulus.

Abstract: An apparatus and method for leakage testing of a pressurized/suction piping system. The apparatus includes a pump assembly for pressurizing the test system formed by the apparatus and the piping system, a pressure source connected to at least one input line assembly, an input line for supplying test fluid to the apparatus, an output line for discharging test fluid, and suitable adapters for connecting the input line assembly to the pipes being tested. In use, the apparatus is installed near the pipeline system to be tested. After all system pumps are turned off and the crash valve on each line is closed, the apparatus is initialized and a test pressure ramping procedure is initiated. The test pressure is maintained for at least approximately 30 minutes. If the measured leakage rate over a 30-minute period is less than a preselected rate, the pipeline system meets applicable standards.

Abstract: A remotely guided brush cutting, chipping and clearing apparatus, dependent upon remote positioning data and radio communication signals, having an apparatus locator system for determining the location of the apparatus and a guidance system for achieving and maintaining the desired direction of travel for the apparatus, relative to the surface of the earth and method for guiding the apparatus.