Patents by Inventor B. Nicholas Oray
B. Nicholas Oray has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20120197272Abstract: A staple line buttress material having an adhesive surface, packaged and provided in sterile, ready-to-use form. The material can be used to retrofit surgical staplers to provide an improved staple line, and with improved ease of use.Type: ApplicationFiled: February 6, 2012Publication date: August 2, 2012Applicant: SYNOVIS LIFE TECHNOLOGIES, INC.Inventors: B. Nicholas Oray, Daniel L. Mooradian
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Publication number: 20100234861Abstract: A staple line buttress material having an adhesive surface, packaged and provided in sterile, ready-to-use form. The material can be used to retrofit surgical staplers to provide an improved staple line, and with improved ease of use.Type: ApplicationFiled: March 22, 2010Publication date: September 16, 2010Applicant: SYNOVIS LIFE TECHNOLOGIES, INC.Inventors: B. Nicholas Oray, Daniel L. Mooradian
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Patent number: 7776060Abstract: A combination medical device comprising a circular stapler instrument (4) and one or more portions of preformed buttress material (16) adapted to be stably positioned upon the staple cartridge (12) and/or anvil (14) components of the stapler (4) prior or at the time of use. Positioned buttress material(s) (16) are delivered to a tissue site where the circular stapler (4) is actuated to connect previously severed tissue portions. An embodiment of the invention allows tissue portions to be joined without the use of sutures. The buttress material (16) is made up of two regions, one of which serves primarily to secure the buttress material (16) to the stapler (4) prior to actuation, and one of which serves primarily to form the improved seal. The former region is severed and discarded upon activation of the circular stapler (4) to form anastomoses, while the remaining material secures and seals the newly connected tissue. Methods of use and preparation of the buttress material (16) are also described.Type: GrantFiled: March 21, 2003Date of Patent: August 17, 2010Assignee: Synovis Life Technologies, Inc.Inventors: Daniel L. Mooradian, B. Nicholas Oray, William F. Kuester
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Patent number: 7144588Abstract: The present invention relates to a method and composition for preventing surgical adhesions during surgery. Tissue surfaces and/or surgical articles involved in the surgery are separated by a biomaterial provided in the form of a non-crosslinked, decellularized and purified mammalian tissue (e.g. bovine pericardium). The biomaterial effectively inhibits fibrosis, scar formation, and surgical adhesions, while also serving as a scaffold for recellularization of the tissue site.Type: GrantFiled: January 17, 2003Date of Patent: December 5, 2006Assignee: Synovis Life Technologies, Inc.Inventors: B. Nicholas Oray, Daniel Mooradian
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Patent number: 7128748Abstract: A combination medical device comprising a circular stapler instrument and one or more portions of preformed buttress material adapted to be stably positioned upon the staple cartridge and/or anvil components of the stapler prior or at the time of use. Positioned buttress material(s) are delivered to a tissue site where the circular stapler is actuated to connect previously severed tissue portions. The buttress material is retained and provides an improved seal between the joined tissue sections. The buttress material is made up of two regions, one of which serves primarily to secure the buttress material to the stapler prior to actuation, and one of which serves primarily to form the improved seal. The former region is severed and discarded upon activation of the circular stapler to form an anastomoses. Methods of use and preparation of the buttress material are also described.Type: GrantFiled: March 26, 2002Date of Patent: October 31, 2006Assignee: Synovis Life Technologies, Inc.Inventors: Daniel L. Mooradian, B. Nicholas Oray
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Publication number: 20050228446Abstract: A combination medical device comprising a circular stapler instrument (4) and one or more portions of preformed buttress material (16) adapted to be stably positioned upon the staple cartridge (12) and/or anvil (14) components of the stapler (4) prior or at the time of use. Positioned buttress material(s) (16) are delivered to a tissue site where the circular stapler (4) is actuated to connect previously severed tissue portions. An embodiment of the invention allows tissue portions to be joined without the use of sutures. The buttress material (16) is made up of two regions, one of which serves primarily to secure the buttress material (16) to the stapler (4) prior to acuation, and one of which serves primarily to form the improved seal. The former region is severed and discarded upon activation of the circular stapler (4) to form anastomoses, while the remaining material secures and seals the newly connected tissue. Methods of use and preparation of the buttress material (16) are also described.Type: ApplicationFiled: March 21, 2003Publication date: October 13, 2005Inventors: Daniel Mooradian, B. Nicholas Oray, William Kuester
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Publication number: 20040141956Abstract: The present invention relates to a method and composition for preventing surgical adhesions during surgery. Tissue surfaces and/or surgical articles involved in the surgery are separated by a biomaterial provided in the form of a non-crosslinked, decellularized and purified mammalian tissue (e.g. bovine pericardium). The biomaterial effectively inhibits fibrosis, scar formation, and surgical adhesions, while also serving as a scaffold for recellularization of the tissue site.Type: ApplicationFiled: January 17, 2003Publication date: July 22, 2004Applicant: Synovis Life Technologies, Inc.Inventors: B. Nicholas Oray, Daniel Mooradian
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Publication number: 20040107006Abstract: A non-crosslinked, decellularized and purified mammalian tissue (e.g., bovine pericardium) having particular use as an implantable resorbable material. The material is treated by alkylating its primary amine groups in a manner sufficient to reduce the antigenicity of the tissue, permitting the treated tissue to be used in vivo and without crosslinking, and in turn, permitting it to be resorbable. The material can be used in surgical repair of soft tissue deficiencies for a certain period of time while the implant itself is gradually remodeled or absorbed by the host. Also provided are a method of preparing such a material, as well as a method of using such a material for surgical repair.Type: ApplicationFiled: November 24, 2003Publication date: June 3, 2004Inventors: Ralph T. Francis, Qing Hong Zhao, Amy Desmith, B. Nicholas Oray
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Patent number: 6652594Abstract: A non-crosslinked, decellularized and purified mammalian tissue (e.g., bovine pericardium) having particular use as an implantable resorbable material. The material is treated by alkylating its primary amine groups in a manner sufficient to reduce the antigenicity of the tissue, permitting the treated tissue to be used in vivo and without crosslinking, and in turn, permitting it to be resorbable. The material can be used in surgical repair of soft tissue deficiencies for a certain period of time while the implant itself is gradually remodeled or absorbed by the host. Also provided are a method of preparing such a material, as well as a method of using such a material for surgical repair.Type: GrantFiled: March 14, 2002Date of Patent: November 25, 2003Assignee: Synovis Life Technologies, Inc.Inventors: Ralph T. Francis, Qing Hong Zhao, Amy DeSmith, B. Nicholas Oray
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Publication number: 20030183671Abstract: A combination medical device comprising a circular stapler instrument and one or more portions of preformed buttress material adapted to be stably positioned upon the staple cartridge and/or anvil components of the stapler prior or at the time of use. Positioned buttress material(s) are delivered to a tissue site where the circular stapler is actuated to connect previously severed tissue portions. The buttress material is retained and provides an improved seal between the joined tissue sections. The buttress material is made up of two regions, one of which serves primarily to secure the buttress material to the stapler prior to actuation, and one of which serves primarily to form the improved seal. The former region is severed and discarded upon activation of the circular stapler to form an anastomoses. Methods of use and preparation of the buttress material are also described.Type: ApplicationFiled: March 26, 2002Publication date: October 2, 2003Inventors: Daniel L. Mooradian, B. Nicholas Oray
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Publication number: 20020138152Abstract: A non-crosslinked, decellularized and purified mammalian tissue (e.g., bovine pericardium) having particular use as an implantable resorbable material. The material is treated by alkylating its primary amine groups in a manner sufficient to reduce the antigenicity of the tissue, permitting the treated tissue to be used in vivo and without crosslinking, and in turn, permitting it to be resorbable. The material can be used in surgical repair of soft tissue deficiencies for a certain period of time while the implant itself is gradually remodeled or absorbed by the host. Also provided are a method of preparing such a material, as well as a method of using such a material for surgical repair.Type: ApplicationFiled: March 14, 2002Publication date: September 26, 2002Inventors: Ralph T. Francis, Qing Hong Zhao, Amy DeSmith, B. Nicholas Oray
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Publication number: 20020123789Abstract: A stent cover useful as a barrier between an expandable stent and the vascular surface. The cover provides an optimal combination of such properties as thickness, physical characteristics and biocompatability. The cover can be formed to and positioned upon the size and shape of the unexpanded stent, and to then be expanded in situ upon expansion of the stent itself. The cover is prepared from natural tissues such as umbilical arteries, bovine pericardium, and porcine peritoneum.Type: ApplicationFiled: May 31, 2001Publication date: September 5, 2002Inventors: Ralph T. Francis, Qing Hong Zhao, B. Nicholas Oray, Anne E. Metzger
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Patent number: 6312474Abstract: A non-crosslinked, decellularized and purified mammalian tissue (e.g., bovine pericardium) having particular use as an implantable resorbable material. The material is treated by alkylating its primary amine groups in a manner sufficient to reduce the antigenicity of the tissue, permitting the treated tissue to be used in vivo and without crosslinking, and in turn, permitting it to be resorbable. The material can be used in surgical repair of soft tissue deficiencies for a certain period of time while the implant itself is gradually remodeled or absorbed by the host. Also provided are a method of preparing such a material, as well as a method of using such a material for surgical repair.Type: GrantFiled: September 15, 1999Date of Patent: November 6, 2001Assignee: Bio-Vascular, Inc.Inventors: Ralph T. Francis, Qing Hong Zhao, Amy Desmith, B. Nicholas Oray