Patents by Inventor B. Nichols Majorie

B. Nichols Majorie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chicken monoclonal antibodies specific for coccidial antigens involved in invasion of host lymphocytes
    Patent number: 6451984
    Abstract: A stable chicken hybridoma secreting a monoclonal antibody (mAb) that detects the conoid structure of Eimeria acervulina (E. acervulina) sporozoites has been developed. The hybridoma is made by fusing a thymidine kinase (TK)-deficient chicken myeloma with spleen cells from chickens immunized with sporozoite antigen. The monoclonal antibody recognizes sporozoite proteins on the conoid of the anterior tip of E. acervulina sporozoites. The monoclonal antibody has been shown to inhibit the invasion of sporozoites into CD8+ T cells in vitro thereby indicating its role in the recognition of host cells during the invasion process following infection with Eimeria parasites.
    Type: Grant
    Filed: September 8, 1995
    Date of Patent: September 17, 2002
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventors: Hyun S. Lillehoj, B. Nichols Majorie