Patents by Inventor B. Vishnuvajjala

B. Vishnuvajjala has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrrolobenzodiazepines
    Publication number: 20080039448
    Abstract: A compound of formula I: or solvate thereof, wherein n is 1 to 10, and M and M? are independently selected from monovalent pharmaceutically acceptable cations, or together represent a divalent pharmaceutically acceptable cation.
    Type: Application
    Filed: January 20, 2006
    Publication date: February 14, 2008
    Applicant: GOVERNMENT OF THE U.S.A. REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES
    Inventors: Paul Liu, B. Vishnuvajjala, Kenneth Snader, David Thurston, Philip Howard, Stephen Gregson
  • Pyrrolobenzodiazepine derivatives, compositions comprising the same and methods related thereto
    Publication number: 20070072846
    Abstract: Disclosed are compounds of Formula (I) wherein X, Y, Ri-R7,T1, T2, Z, and p are as described herein; a pharmaceutical composition comprising a compound of Formula (I) and a carrier; a method of inhibiting growth of a cell, which method comprises administering in an amount effective to inhibit growth a compound of Formula (I); a method of treating cancer in a mammal, which method comprises administering in an amount effective to treat cancer a compound of Formula (I); a method of treating a viral, parasitic, or bacterial infection of a cell, which method comprises administering in an amount effective to treat a viral, parasitic, or bacterial infection a compound of Formula (I); and a method of preparing a compound of Formula (I) as described herein.
    Type: Application
    Filed: October 22, 2004
    Publication date: March 29, 2007
    Inventors: B. Vishnuvajjala, Paul Liu, Kenneth Snader, David Thurston, Philip Howard, Luke Hsiao, Gregory Turner
  • Pyrrolobenzodiazepines
    Publication number: 20060270661
    Abstract: A compound of formula I: or solvate thereof, wherein n is 1 to 10, and M and M? are independently selected from monovalent pharmaceutically acceptable cations, or together represent a divalent pharmaceutically acceptable cation.
    Type: Application
    Filed: May 13, 2005
    Publication date: November 30, 2006
    Applicant: GOVERNMENT OF THE USA, REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES
    Inventors: Paul Liu, B. Vishnuvajjala, Kenneth Snader, David Thurston, Philip Howard, Stephen Gregson
  • Pharmaceutical compositions of safingol and methods of using the same
    Publication number: 20050187186
    Abstract: The present invention provides stable aqueous solutions consisting essentially of: (a) a sphingolipid; (b) lactic acid; and (c) optionally a stabilizing agent; wherein the solution has a molar ratio of lactic acid to sphingolipid of 1:1 to 10:1. The present invention further provides an emulsion formulation consisting essentially of: (a) lactic acid; (b) a sphingolipid, wherein the sphingolipid is present in an amount of about 0.1 to about 30 mg/ml of emulsion; (b) optionally an isotonic agent; and (c) a phospholipid present in an amount of about 0.2 to about 200 mg/ml of emulsion. Methods of making and using the compositions are also provided.
    Type: Application
    Filed: February 19, 2004
    Publication date: August 25, 2005
    Inventors: Barry Maurer, Shanker Gupta, C. Reynolds, B. Vishnuvajjala