Patents by Inventor Babita Agrawal

Babita Agrawal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunomodulatory compositions and methods of use thereof
    Patent number: 11701393
    Abstract: The present disclosure provides immunomodulatory compositions comprising live Caulobacter crescentus (CC). Immunomodulatory compositions of the present disclosure are useful for modulating an immune response in an individual. The present disclosure thus provides methods of modulating an immune response in an individual, involving administering an immunomodulatory composition comprising live CC to the individual.
    Type: Grant
    Filed: August 11, 2022
    Date of Patent: July 18, 2023
    Inventors: Babita Agrawal, Rakesh Kumar, Nancy Gupta
  • IMMUNOMODULATORY COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20230084577
    Abstract: The present disclosure provides immunomodulatory compositions comprising live Caulobacter crescentus (CC). Immunomodulatory compositions of the present disclosure are useful for modulating an immune response in an individual. The present disclosure thus provides methods of modulating an immune response in an individual, involving administering an immunomodulatory composition comprising live CC to the individual.
    Type: Application
    Filed: August 11, 2022
    Publication date: March 16, 2023
    Inventors: Babita AGRAWAL, Rakesh KUMAR, Nancy GUPTA
  • Immunomodulatory compositions and methods of use thereof
    Patent number: 11419904
    Abstract: The present disclosure provides immunomodulatory compositions comprising live Caulobacter crescentus (CC). Immunomodulatory compositions of the present disclosure are useful for modulating an immune response in an individual. The present disclosure thus provides methods of modulating an immune response in an individual, involving administering an immunomodulatory composition comprising live CC to the individual.
    Type: Grant
    Filed: July 12, 2021
    Date of Patent: August 23, 2022
    Inventors: Babita Agrawal, Rakesh Kumar, Nancy Gupta
  • IMMUNOMODULATORY COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20210369792
    Abstract: The present disclosure provides immunomodulatory compositions comprising live Caulobacter crescentus (CC). Immunomodulatory compositions of the present disclosure are useful for modulating an immune response in an individual. The present disclosure thus provides methods of modulating an immune response in an individual, involving administering an immunomodulatory composition comprising live CC to the individual.
    Type: Application
    Filed: July 12, 2021
    Publication date: December 2, 2021
    Inventors: Babita AGRAWAL, Rakesh KUMAR, Nancy GUPTA
  • Immunomodulatory compositions and methods of use thereof
    Patent number: 11065283
    Abstract: The present disclosure provides immunomodulatory compositions comprising live Caulobacter crescentus (CC). Immunomodulatory compositions of the present disclosure are useful for modulating an immune response in an individual. The present disclosure thus provides methods of modulating an immune response in an individual, involving administering an immunomodulatory composition comprising live CC to the individual.
    Type: Grant
    Filed: August 22, 2016
    Date of Patent: July 20, 2021
    Inventors: Babita Agrawal, Rakesh Kumar, Nancy Gupta
  • Immunomodulatory compositions and methods of use thereof
    Patent number: 10946082
    Abstract: The present disclosure provides immunomodulatory compositions comprising heat-killed Caulobacter crescentus (HKCC). Immunomodulatory compositions of the present disclosure are useful for modulating an immune response in an individual. The present disclosure thus provides methods of modulating an immune response in an individual, involving administering an immunomodulatory composition comprising HKCC to the individual.
    Type: Grant
    Filed: July 15, 2019
    Date of Patent: March 16, 2021
    Inventors: Babita Agrawal, Rakesh Kumar
  • IMMUNOMODULATORY COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20200054731
    Abstract: The present disclosure provides immunomodulatory compositions comprising heat-killed Caulobacter crescentus (HKCC). Immunomodulatory compositions of the present disclosure are useful for modulating an immune response in an individual. The present disclosure thus provides methods of modulating an immune response in an individual, involving administering an immunomodulatory composition comprising HKCC to the individual.
    Type: Application
    Filed: July 15, 2019
    Publication date: February 20, 2020
    Inventors: Babita AGRAWAL, Rakesh KUMAR
  • Immunomodulatory compositions and methods of use thereof
    Patent number: 10369205
    Abstract: The present disclosure provides immunomodulatory compositions comprising heat-killed Caulobacter crescentus (HKCC). Immunomodulatory compositions of the present disclosure are useful for modulating an immune response in an individual. The present disclosure thus provides methods of modulating an immune response in an individual, involving administering an immunomodulatory composition comprising HKCC to the individual.
    Type: Grant
    Filed: January 7, 2015
    Date of Patent: August 6, 2019
    Inventors: Babita Agrawal, Rakesh Kumar
  • IMMUNOMODULATORY COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20180243347
    Abstract: The present disclosure provides immunomodulatory compositions comprising live Caulobacter crescentus (CC). Immunomodulatory compositions of the present disclosure are useful for modulating an immune response in an individual. The present disclosure thus provides methods of modulating an immune response in an individual, involving administering an immunomodulatory composition comprising live CC to the individual.
    Type: Application
    Filed: August 22, 2016
    Publication date: August 30, 2018
    Inventors: Babita AGRAWAL, Rakesh KUMAR, Nancy GUPTA
  • METHODS OF INDUCING AN IMMUNE RESPONSE TO HEPATITIS C VIRUS
    Publication number: 20180000926
    Abstract: The present disclosure provides methods for inducing an immune response to hepatitis C virus (HCV) in an individual. The present disclosure provides methods for treating an HCV infection in an individual.
    Type: Application
    Filed: January 15, 2016
    Publication date: January 4, 2018
    Inventors: Babita Agrawal, Rakesh Kumar, Shakti Singh
  • IMMUNOMODULATORY COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20160317637
    Abstract: The present disclosure provides immunomodulatory compositions comprising heat-killed Caulobacter crescentus (HKCC). Immunomodulatory compositions of the present disclosure are useful for modulating an immune response in an individual. The present disclosure thus provides methods of modulating an immune response in an individual, involving administering an immunomodulatory composition comprising HKCC to the individual.
    Type: Application
    Filed: January 7, 2015
    Publication date: November 3, 2016
    Inventors: Babita Agrawal, Rakesh Kumar
  • Antiviral nucleosides
    Patent number: 8227594
    Abstract: Disclosed are nucleosides which are useful in diagnosing and treating viral infections, for example, infections caused by hepatitis B virus (HBV), and herpes viruses including Epstein Barr virus.
    Type: Grant
    Filed: May 18, 2009
    Date of Patent: July 24, 2012
    Inventors: Rakesh Kumar, Babita Agrawal, D. Lorne J. Tyrrell
  • ANTIVIRAL NUCLEOSIDES
    Publication number: 20100130440
    Abstract: Disclosed are nucleosides which are useful in diagnosing and treating viral infections, for example, infections caused by hepatitis B virus (HBV), and herpes viruses including Epstein Barr virus.
    Type: Application
    Filed: May 18, 2009
    Publication date: May 27, 2010
    Inventors: Rakesh Kumar, Babita Agrawal, D. Lorne J. Tyrrell
  • Antiviral nucleosides
    Patent number: 7589077
    Abstract: Disclosed are nucleosides which are useful in diagnosing and treating viral infections, for example, infections caused by hepatitis B virus (HBV), and herpes viruses including Epstein Barr virus.
    Type: Grant
    Filed: May 17, 2002
    Date of Patent: September 15, 2009
    Inventors: Rakesh Kumar, Babita Agrawal, D. Lorne J. Tyrrell
  • Antiviral nucleosides
    Publication number: 20040242533
    Abstract: Disclosed are nucleosides which are useful in dignosing and treating viral infections, for example, infections caused by hepatitis B virus (HBV), and herpes viruses including Epstein Barr virus.
    Type: Application
    Filed: June 29, 2004
    Publication date: December 2, 2004
    Inventors: Rakesh Kumar, Babita Agrawal, D. Orne J. Tyrrell
  • Methods of detecting T-cell activation
    Patent number: 6602660
    Abstract: Methods of detecting activated T-cells involve monitoring levels of MUC-1 mucin expression at the protein and/or mRNA level. Compositions for modulating immune function contain compounds that modulate the expression or function of MUC-1. Methods of treating disorders associated an inappropriate state of T-cell activation involve contacting a T-cell with a compound containing an inhibitor of MUC-1 expression or function.
    Type: Grant
    Filed: August 30, 2000
    Date of Patent: August 5, 2003
    Inventors: Babita Agrawal, B. Michael Longenecker
  • Lipid-modified muc-1 derivatives
    Patent number: 6600012
    Abstract: A method for generating a mixture of activated T-cells by combining a plurality of peripheral blood lymphocytes (PBLs) with an antigen-loaded liposome to produce antigen-loaded PBLs, and combining the antigen-loaded PBLs with a naive, anergic or memory T-cell, to produce an activated T-cell. Such activation is carried out in vivo or in vitro. The antigen-loaded PBLs and activated T-cells, prepared according to the methods of invention, have use as cellular vaccines for treatment of cancer and viral diseases.
    Type: Grant
    Filed: February 3, 2000
    Date of Patent: July 29, 2003
    Assignee: Biomira, Inc.
    Inventors: Babita Agrawal, Mark J. Krantz, Mark A. Reddish, B. Michael Longenecker
  • Small peptide-based therapeutics for reversing cancer-associated MUC-1 mucin-induced immunosuppression
    Publication number: 20020159969
    Abstract: The invention relates to derivatives of MUC-1 mucin which are particularly useful in relieving states of anergy or immunosuppression. MUC-1 derivatives, pharmaceutical compositions containing them, and methods of using them are also provided.
    Type: Application
    Filed: October 29, 2001
    Publication date: October 31, 2002
    Inventors: Babita Agrawal, Bryan Michael Longenecker, Mark Austin Reddish
  • MUC-1 antagonists and methods of treating immune disorders
    Publication number: 20020142983
    Abstract: The invention provides compounds and compositions of containing intracellular inhibitors of the mucin MUC-1. These intracellular MUC-1 inhibitors are exemplified by protein-based inhibitors that contain a targeting and/or an internalization domain, and by antisense nucleic acids. These inhibitors are useful in methods of treating autoimmune disorders.
    Type: Application
    Filed: October 29, 2001
    Publication date: October 3, 2002
    Applicant: BIOMIRA, INC.
    Inventors: Babita Agrawal, B. Michael Longenecker
  • Lipopeptide adjuvants
    Publication number: 20020018806
    Abstract: Vaccine compositions containing a MUC-1-based adjuvant and an antigen are useful in treating and preventing disorders such as cancer and viral diseases. Exemplary compositions contain a 25-amino acid lipopeptide adjuvant and an antigen of interest in association with a liposome.
    Type: Application
    Filed: March 23, 2001
    Publication date: February 14, 2002
    Inventors: Babita Agrawal, Michael B. Longenecker, Joanne Parker