Patents by Inventor Bachra Rokbi

Bachra Rokbi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Meningococcal vaccine based on lipooligosaccharide (LOS) originating from modified Neisseria meningitidis strains of immunotype L6
    Publication number: 20100330160
    Abstract: The invention especially relates to multivalent vaccine compositions that can treat or prevent at least 60, preferably 75% of infections caused by Neisseria meningitidis especially of serogroup B. To this end, the invention in particular provides a lipooligosaccharide (LOS) of N. meningitidis in particular constituted by a lipid A, an inner core, an ? chain of L6 or L8 type, in which the heptose II residue of the inner core bears in position O-3 and in position O-6 or O-7 a phosphoethanolamine (PEA) substituent, and also to the construction of the strain of N. meningitidis that is capable of expressing such an LOS. The invention also relates to a strain of N. meningitidis of serogroup A that bears a lipooligosaccharide (LOS) in particular constituted by a lipid A, an inner core, an ? chain of L6 type, in which the heptose II residue of the inner core bears in position O-3 a phosphoethanolamine (PEA) substituent and does not bear a PEA substituent in positions O-6 and O-7.
    Type: Application
    Filed: May 14, 2010
    Publication date: December 30, 2010
    Applicant: Sanofi Pasteur
    Inventors: Noëlle Mistretta, Monique Moreau, Geneviève Renauld-Mongenie, Bachra Rokbi
  • Method for the Production of Overproducing Staphylococcus Aureus Strains
    Publication number: 20100330656
    Abstract: The present invention relates to a method for the production of an overproducing Staphylococcus aureus strain comprising: (a) culturing a Staphylococcus aureus strain on a culture medium M1, M2 or M3, (b) optionally, recovering the strains thus produced from the culture medium, and also to the use of said strains for the production of polysaccharides.
    Type: Application
    Filed: September 13, 2010
    Publication date: December 30, 2010
    Applicant: SANOFI PASTEUR SA
    Inventors: Bachra Rokbi, Céline Lafont
  • NUCLEIC ACIDS AND POLYPEPTIDES SPECIFIC OF THE NEISSERIA GENUS PATHOGENIC STRAINS
    Publication number: 20100184639
    Abstract: The invention concerns nucleic acids coding for polypeptides specific of the Neisseria genus pathogenic strains, the corresponding polypeptides, and their diagnostic and therapeutic applications.
    Type: Application
    Filed: February 4, 2010
    Publication date: July 22, 2010
    Inventors: Luc AUJAME, Annabelle Bouchardon, Geneviève Renauld-Mongenie, Bachra Rokbi, Xavier Nassif, Colin Tinsley, Agnes Perrin
  • Nucleic acids and polypeptides specific for pathogenic strains of the genus
    Patent number: 7704513
    Abstract: The invention concerns nucleic acids coding for polypeptides specific of the Neisseria genus pathogenic strains, the corresponding polypeptides, and their diagnostic and therapeutic applications.
    Type: Grant
    Filed: March 27, 2008
    Date of Patent: April 27, 2010
    Assignees: Aventis Pasteur, Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Luc Aujame, Annabelle Bouchardon, Geneviève Renauld-Mongenie, Bachra Rokbi, Xavier Nassif, Colin Tinsley, Agnès Perrin
  • NUCLEIC ACIDS AND POLYPEPTIDES SPECIFIC FOR PATHOGENIC STRAINS OF THE NEISSERIA GENUS
    Publication number: 20090155886
    Abstract: The invention concerns nucleic acids coding for polypeptides specific of the Neisseria genus pathogenic strains, the corresponding polypeptides, and their diagnostic and therapeutic applications.
    Type: Application
    Filed: March 27, 2008
    Publication date: June 18, 2009
    Inventors: Luc AUJAME, Annabelle Bouchardon, Genevieve Renauld-Mongenie, Bachra Rokbi, Xavier Nassif, Colin Tinsley, Agnes Perrin
  • CULTURE MEDIUM FOR HAEMOPHILUS INFLUENZAE TYPE B
    Publication number: 20090017074
    Abstract: The invention relates to a culture medium for Haemophilus influenzae type b, characterized in that the source of protein nitrogen is of non-animal origin and comprises at least one plant peptone and in that the heme source consists of protoporphyrin IX. This medium serves in particular for the production of polyribosyl phosphate (PRP) and for the manufacture of a vaccine against Haemophilus influenzae type b meningitis.
    Type: Application
    Filed: July 10, 2008
    Publication date: January 15, 2009
    Applicant: SANOFI PASTEUR SA
    Inventors: Ghislaine Maitre-Wilmotte, Denis Speck, Bachra Rokbi
  • Nucleic acids and polypeptides specific for pathogenic strains of the genus
    Patent number: 7384768
    Abstract: The invention concerns nucleic acids coding for polypeptides specific of the Neisseria genus pathogenic strains, the corresponding polypeptides, and their diagnostic and therapeutic applications.
    Type: Grant
    Filed: August 3, 2004
    Date of Patent: June 10, 2008
    Assignees: Aventis Pasteur, Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Luc Aujame, Annabelle Bouchardon, Geneviève Renauld-Mongenie, Bachra Rokbi, Xavier Nassif, Colin Tinsley, Agnès Perrin
  • Method for the production of overproducing Staphylococcus aureus strains
    Publication number: 20070031939
    Abstract: The present invention relates to a method for the production of an overproducing Staphylococcus aureus strain comprising: (a) culturing a Staphylococcus aureus strain on a culture medium M1, M2 or M3, (b) optionally, recovering the strains thus produced from the culture medium, and also to the use of said strains for the production of polysaccharides.
    Type: Application
    Filed: April 21, 2006
    Publication date: February 8, 2007
    Applicant: Sanofi Pasteur SA
    Inventors: Bachra Rokbi, Celine Lafont
  • Nucleic acids and polypeptides specific for pathogenic strains of the Neisseria genus
    Publication number: 20050032103
    Abstract: The invention concerns nucleic acids coding for polypeptides specific of the Neisseria genus pathogenic strains, the corresponding polypeptides, and their diagnostic and therapeutic applications.
    Type: Application
    Filed: August 3, 2004
    Publication date: February 10, 2005
    Inventors: Luc Aujame, Annabelle Bouchardon, Genevieve Renauld-Mongenie, Bachra Rokbi, Xavier Nassif, Colin Tinsley, Agnes Perrin
  • Nucleic acids and polypeptides specific of the neisseria genus pathogenic strains
    Patent number: 6835384
    Abstract: The invention concerns nucleic acids coding for polypeptides specific of the Neisseria genus pathogenic strains, the corresponding polypeptides, and their diagnostic and therapeutic applications.
    Type: Grant
    Filed: August 16, 2001
    Date of Patent: December 28, 2004
    Assignees: Aventis Pasteur, Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Luc Aujame, Annabelle Bouchardon, Geneviève Renauld-Mongenie, Bachra Rokbi, Xavier Nassif, Colin Tinsley, Agnès Perrin