Patents by Inventor Baerbel Rohrer

Baerbel Rohrer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ISATIN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF DEGENERATIVE DISEASES AND DISORDERS
    Publication number: 20140275075
    Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of degenerative diseases and disorders.
    Type: Application
    Filed: March 13, 2013
    Publication date: September 18, 2014
    Applicant: MUSC FOUNDATION FOR RESEARCH DEVELOPMENT
    Inventors: Craig C. BEESON, Christopher C. LINDSEY, Yuri K. PETERSON, Baerbel ROHRER
  • TARGETING COMPLEMENT FACTOR H FOR TREATMENT OF DISEASES
    Publication number: 20140073572
    Abstract: The invention provides a CR2-FH molecule comprising a CR2 portion comprising CR2 protein or a fragment thereof and a FH portion comprising a factor H protein or a fragment thereof, and pharmaceutical compositions comprising a CR2-FH molecule. Also provided are methods of using the compositions for treatment diseases in which the alternative complement pathway is implicated, such as age-related macular degeneration, rheumatoid arthritis, and ischemia reperfusion.
    Type: Application
    Filed: October 1, 2013
    Publication date: March 13, 2014
    Applicants: MUSC Foundation for Research Development, The Regents of the University of Colorado, a Body Corporate
    Inventors: Gary GILKESON, Stephen Tomlinson, V. Michael Holers, Baerbel Rohrer
  • ALPHA CONNEXIN C-TERMINAL (ACT) PEPTIDES FOR TREATING AGE-RELATED MACULAR DEGENERATION
    Publication number: 20140018305
    Abstract: Provided herein are compositions and methods for use in treating or preventing macular degeneration in a subject.
    Type: Application
    Filed: July 5, 2013
    Publication date: January 16, 2014
    Inventors: Baerbel ROHRER, Robert GOURDIE, Gautam GHATNEKAR
  • Targeting complement factor H for treatment of diseases
    Patent number: 8569225
    Abstract: The invention provides a CR2-FH molecule comprising a CR2 portion comprising CR2 protein or a fragment thereof and a FH portion comprising a factor H protein or a fragment thereof, and pharmaceutical compositions comprising a CR2-FH molecule. Also provided are methods of using the compositions for treatment diseases in which the alternative complement pathway is implicated, such as age-related macular degeneration, rheumatoid arthritis, and ischemia reperfusion.
    Type: Grant
    Filed: May 18, 2010
    Date of Patent: October 29, 2013
    Assignees: MUSC Foundation for Research Development, The Regents of the University of Colorado, a body corporate
    Inventors: Gary Gilkeson, Stephen Tomlinson, V. Michael Holers, Baerbel Rohrer
  • Compositions and Methods for the Treatment of Degenerative Diseases
    Publication number: 20130137728
    Abstract: Disclosed are compounds or pharmaceutically acceptable salts thereof, having the structure of formula I. Also disclosed are methods of preventing and/or treating degenerative disease in a subject, comprising administering to said subject a therapeutically effective amount of a compound of formula I, or a pharmaceutically acceptable salt thereof. Also disclosed are pharmaceutical compositions for preventing and/or treating de-generative disease in a subject comprising a therapeutically effective amount of a compound of formula I, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: March 24, 2011
    Publication date: May 30, 2013
    Applicant: MUSC Foundation For Research And Development
    Inventors: Craig Cano Beeson, Baerbel Rohrer, Nathan Perron
  • ALPHA CONNEXIN C-TERMINAL (ACT) PEPTIDES FOR TREATING AGE-RELATED MACULAR DEGENERATION
    Publication number: 20110130345
    Abstract: Provided herein are compositions and methods for use in treating or preventing macular degeneration in a subject.
    Type: Application
    Filed: June 23, 2008
    Publication date: June 2, 2011
    Inventors: Baerbel Rohrer, Robert Gourdie
  • TARGETING COMPLEMENT FACTOR H FOR TREATMENT OF DISEASES
    Publication number: 20110015127
    Abstract: The invention provides a CR2-FH molecule comprising a CR2 portion comprising CR2 protein or a fragment thereof and a FH portion comprising a factor H protein or a fragment thereof, and pharmaceutical compositions comprising a CR2-FH molecule. Also provided are methods of using the compositions for treatment diseases in which the alternative complement pathway is implicated, such as age-related macular degeneration, rheumatoid arthritis, and ischemia reperfusion.
    Type: Application
    Filed: May 18, 2010
    Publication date: January 20, 2011
    Inventors: Gary GILKESON, Stephen TOMLINSON, V. Michael HOLERS, Baerbel ROHRER
  • Targeting complement factor H for treatment of diseases
    Patent number: 7759304
    Abstract: The invention provides a CR2-FH molecule comprising a CR2 portion comprising CR2 protein or a fragment thereof and a FH portion comprising a factor H protein or a fragment thereof, and pharmaceutical compositions comprising a CR2-FH molecule. Also provided are methods of using the compositions for treatment diseases in which the alternative complement pathway is implicated, such as age-related macular degeneration, rheumatoid arthritis, and ischemia reperfusion.
    Type: Grant
    Filed: June 21, 2007
    Date of Patent: July 20, 2010
    Assignees: Regents of the University of Colorado, MUSC Foundation For Research Development
    Inventors: Gary Gilkeson, Stephen Tomlinson, V. Michael Holers, Baerbel Rohrer
  • Targeting complement factor H for treatment of diseases
    Publication number: 20080221011
    Abstract: The invention provides a CR2-FH molecule comprising a CR2 portion comprising CR2 protein or a fragment thereof and a FH portion comprising a factor H protein or a fragment thereof, and pharmaceutical compositions comprising a CR2-FH molecule. Also provided are methods of using the compositions for treatment diseases in which the alternative complement pathway is implicated, such as age-related macular degeneration, rheumatoid arthritis, and ischemia reperfusion.
    Type: Application
    Filed: June 21, 2007
    Publication date: September 11, 2008
    Inventors: Gary Gilkeson, Stephen Tomlinson, V. Michael Holers, Baerbel Rohrer