Patents by Inventor Bagirath Gangadharan

Bagirath Gangadharan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ADENO-ASSOCIATED VIRUS VECTORS BASED GENE THERAPY FOR HEREDITARY ANGIOEDEMA
    Publication number: 20230043051
    Abstract: The present disclosure provides, among other things, a recombinant adeno-associated virus (rAAV) vector comprising an AAV8 capsid and a codon-optimized SERPING1 sequence encoding a human C1-esterase inhibitor. The disclosure also provides a method of treating a subject having Hereditary angioedema (HAE), comprising administering to the subject in need thereof a recombinant adeno-associated virus (rAAV) vector comprising an AAV8 capsid, and codon-optimized SERPING1 sequences encoding a human C1-esterase inhibitor.
    Type: Application
    Filed: October 23, 2020
    Publication date: February 9, 2023
    Inventors: Matthias Klugmann, Franziska Horling, Johannes Lengler, Patrice Douillard, Friedrich Scheiflinger, Hanspeter Rottensteiner, Bagirath Gangadharan