Abstract: This disclosure relates amide-sulfamide compounds disclosed herein and uses related to CXCR4 inhibition. In certain embodiments, the compounds have formula I, salts, derivatives, and prodrugs thereof wherein, A is a bridging aryl or heterocyclyl and R1 and R2 are further disclosed herein. In certain embodiments, the disclosure contemplates pharmaceutical compositions comprising compounds disclosed herein. In certain embodiments, the disclosure relates to methods of treating or preventing CXCR4 related diseases or conditions by administering an effective amount of a compound disclosed herein to a subject in need thereof.

Abstract: The present invention discloses a motor-magnetostrictive actuator hybrid brake-by-wire system. The system includes a motor, a transmission mechanism, a magnetostrictive-driving piston mechanism and a floating-caliper disc mechanism. The transmission mechanism includes a planetary gear set and a screw set, and is driven by the motor. The linear motion of the sleeve is achieved by the planetary gear set and screw set. The sleeve pushes forward the piston head of the magnetostrictive-driving piston mechanism and the piston head pushes forward the brake pad back plate of the floating-caliper disc mechanism to clamp the brake disc, which accomplishes braking.

Abstract: A polymer resin comprising: (a) quantum dots, (b) a compound of formula (I) (I) wherein R1 is hydrogen or methyl and R2 is a C6-C20 aliphatic polycyclic substituent, and (c) a block or graft copolymer having Mn from 50,000 to 400,000 and comprising from 10 to 100 wt % polymerized units of styrene and from 0 to 90 wt % of a non-styrene block; wherein the non-styrene block has a van Krevelen solubility parameter from 15.0 to 17.5 (J/cm3)1/2.

Abstract: The present disclosure provides a display substrate, a display panel and a display device. The display substrate forms a cell with an opposite substrate. A black matrix is arranged on the display substrate or the opposite substrate. The display substrate includes a base substrate and a photoluminescent device arranged on the base substrate. The photoluminescent device is arranged at a position corresponding to the black matrix and located at a side of the black matrix facing a backlight module. A projection of the photoluminescent device onto the base substrate at least partially overlaps a projection of the black matrix onto the base substrate. The photoluminescent device is configured to emit light under an excitation of a light beam.

Abstract: A food taste simulation method, applied in a food taste simulation system, comprising: determining food information of target food according to a food simulation trigger signal when receiving the food simulation trigger signal; determining airflow for simulating the taste of the target food according to the food information; and releasing the airflow through an airflow chip disposed in the oral cavity according to the airflow. The safety of food simulation is improved and the effect of food simulation is enriched in this method. A food taste simulation system is also provided.

Abstract: A method for determining a calibration parameter of a zero intermediate frequency radio receiver, and a zero intermediate frequency radio receiver are provided. The method includes: obtaining a plurality of sub-band training signals, where a sum of the plurality of sub-band training signals is a fullband training signal; determining a sub-band calibration parameter corresponding to each of the plurality of sub-band training signals; determining a fullband calibration signal according to the plurality of sub-band training signals and the sub-band calibration parameter corresponding to each of the plurality of sub-band training signals; and performing coefficient fitting on the fullband training signal and the fullband calibration signal, to determine a fullband calibration parameter. Because sub-band calibration parameters are obtained according to a plurality of different sub-band training signals, aliasing between an image signal and a training signal is reduced.

Abstract: A common-stator macro/micro integrated precision motion one-dimensional linear motor assembly, includes a base, linear guide rails, slide blocks, a U-shaped linear motor stator, a macro motion rotor, a micro motion rotor and a macro/micro integrated platform. A macro and micro motion platforms are connected to form an integrated platform through an elastic member, an outer frame of the macro/micro integrated platform is mounted on the linear guide rails and the slide blocks, the U-shaped linear motor stator is arranged on the base, rotors are respectively mounted on the macro and micro motion platforms, and large-scale overall high-speed motion can be realized when macro and micro rotors are simultaneously driven, and when a motion deviation occurs, the micro motion platform realizes precise displacement output by virtue of elastic deformation due to small inertia and zero friction, and high-frequency motion deviation compensation can be realized by virtue of individual drive.

Abstract: In an embodiment, a processor includes: a plurality of first cores to independently execute instructions, each of the plurality of first cores including a plurality of counters to store performance information; at least one second core to perform memory operations; and a power controller to receive performance information from at least some of the plurality of counters, determine a workload type executed on the processor based at least in part on the performance information, and based on the workload type dynamically migrate one or more threads from one or more of the plurality of first cores to the at least one second core for execution during a next operation interval. Other embodiments are described and claimed.

Abstract: The present invention relates to the field of drilling fluids, and discloses a drilling fluid that can inhibit surface hydration of clay and a preparation method of the drilling fluid. The drilling fluid contains water, bentonite, an intercalation inhibitor, a tackifier, a flow pattern regulator, a filtrate reducer, a lubricant, and a weighting agent, wherein, based on 100 parts by weight of water, the content of the bentonite is 2-9 parts by weight, the content of the intercalation inhibitor is 0.3-4 parts by weight, the content of the tackifier is 1-10 parts by weight, the content of the flow pattern regulator is 0.8-7 parts by weight, the content of the filtrate reducer is 1-8 parts by weight, the content of the lubricant is 0.

Abstract: The present invention is concerned with PCR-based detection methods and kits for the identification, differentiation, and quantification of different bacterial strains (e.g., Gram-negative bacterial strains), and also association of two or more PCR-positive genes to a single genome. The methods generally comprise carrying out PCR reactions using at least a first PCR primer set and/or probe for at least one target nucleic acid; and a second PCR primer set and/or probe for at least a second target nucleic acid. Positive PCR reaction products are then detected to determine test samples containing positive PCR reaction products for both the first and second target nucleic acids. This information can be used to calculate the gene association rate to determine whether the sample contains, for example, Shiga toxin-producing E. coli of the O-type serogroup.

Abstract: A gel plugging slurry for well drilling, comprising water, special gel, bridging material, linking material, and packing material, wherein based on 100 parts by weight of the water, the amount of the special gel is 1-15 parts by weight, the amount of the bridging material is 8-20 parts by weight, the amount of the linking material is 20-40 parts by weight, and the amount of the packing material is 25-45 parts by weight. The gel slug plugging method including simple operation and low requirement for ambient environment; besides, the bridging material, linking material and packing material in the gel plugging slurry form stable structures in the gel, and thereby the gel plugging effect can be improved effectively.

Abstract: The present invention proposes a macro-micro integrated compound platform with adjustable dynamic characteristics. When a macro platform mover and a micro platform mover are driven at the same time, the whole large-scale high-speed motion can be realized; when a motion deviation occurs, a micro motion platform can be driven separately to realize the high-frequency motion deviation compensation, because the micro motion platform has small inertia and zero friction and achieves precision displacement output through elastic deformation.

Abstract: The present invention provides an apparatus and a method in a radio communications system. The apparatus in a radio communications system comprises an estimation unit and a statistics collection unit. The estimation unit is used for estimating a signal receiving strength of each of multiple transmission positions, compared with a signal transmission strength of each of one or more possible transmission positions of a first-type node of a to-be-test communications system on a transmission resource block. The statistics collection unit is used for collecting, according the estimation result, statistics on power space distribution of the first-type node of the to-be-tested communications system.

Abstract: The present application discloses A thin film transistor (TFT), including: a substrate; a source-drain layer comprising a source electrode and a drain electrode over the substrate; and an active layer comprising a poly-Si pattern and an amorphous-Si pattern having contact with the poly-Si pattern over the substrate. The amorphous-Si pattern is between the poly-Si pattern and the source-drain layer; the source electrode overlaps with the poly-Si pattern and the amorphous-Si pattern respectively in a direction substantially perpendicular to a surface of the substrate; and the drain electrode overlaps with the poly-Si pattern and the amorphous-Si pattern respectively in the direction substantially perpendicular to the surface of the substrate.

Abstract: A method to estimate range to a moving rigid body from a moving platform using a monocular camera. The method does not require the camera platform to maneuver in order to estimate range. The method relies on identification and tracking of certain principal features of the object. The method extracts a silhouette of an object from an obtained image and identifies two principal linear components of the silhouette. A normalized distance between the point of intersection of the two linear components and a centroid of the silhouette is computed, compared to a data set and used to determine a direction of movement of the object.

Abstract: A method for processing session and a device thereof, a server and a storage medium are provided. The method includes: capturing packets sent from a client associated with the session; reconstituting a packet flow of the session from the captured packets based on quintets of the packets, wherein the quintet comprises a source address, a destination address, a source port, a destination port and a protocol number of the packet; extracting a behavior attribute of the client from the packet flow; determining that the behavior attribute of the client is beyond a baseline; and interrupting the session with the client.

Abstract: A computing device receives a voice command to perform an action within a document. An interpretation of the voice command is mapped to a set of commands. Disambiguation is automatically performed by conducting a user experience to receive additional information.

Abstract: A wireless positioning apparatus is disclosed, which includes at least one first device and at least one second device. Each first device is disposed on each moving object and is configured to transmit a wireless signal. Each second device is disposed on a fixed position and is configured to detect a strength of the wireless signal of each first device. The wireless positioning apparatus further includes a data processor, which is configured to receive the strength of the wireless signal of each first device detected by each second device, to calculate a distance between each first device and each second device, and to ultimately determine a position of each first device to thereby realize the positioning of each moving object. A wireless positioning method and a sports training apparatus comprising the wireless positioning apparatus are also provided in the disclosure.