Patents by Inventor Bailey Arruda

Bailey Arruda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240139306
    Abstract: Disclosed herein are methods for detecting and producing PoMV. Further, disclosed herein are immunogenic and/or vaccine compositions and methods for treating or preventing PoMV. The compositions and methods include immunogenic portions of PoMV including entry proteins. In at least particular cases, a mutated version of a portion of the PoMV is utilized, such as a deglycosylated, or amino acid substituted mutant of the spike protein.
    Type: Application
    Filed: March 1, 2022
    Publication date: May 2, 2024
    Inventors: Ganwu Li, Bailey Arruda, Huigang Shen, Ying Zheng
  • Patent number: 11896659
    Abstract: The present invention relates to the use of an immunogenic composition that comprises a porcine circovirus type 3 (PCV3) antigen for treatment of several clinical manifestations (diseases). Preferably, the clinical manifestations are associated with a PCV3 infection.
    Type: Grant
    Filed: November 23, 2022
    Date of Patent: February 13, 2024
    Inventors: Arun Iyer, Luis Alejandro Hernandez, Abby Patterson, Bailey Arruda, Luis Gabriel Gimenez-Lirola, Dave Michael Anstrom, Eric M. Vaughn, Pablo E Pineyro Pineiro, Troy James Kaiser, Joseph Ralph Hermann
  • Patent number: 11891417
    Abstract: The present invention is directed to novel polynucleotides, polypeptides, and polyproteins of Mycoplasma surface proteins, all of which are useful in detecting infection and for the preparation of vaccines for treating and preventing diseases in swine and other animals. Vaccines provided according to the practice of the invention are effective against Mycoplasma infections. Detection and therapeutic polyclonal and monoclonal antibodies are also a feature of the present invention. Assays, kits, systems, and nanoparticle encapsulated compositions related to the polynucleotides, polypeptides, polyproteins, antibodies or fragments, derivatives, and variants thereof are also disclosed.
    Type: Grant
    Filed: November 3, 2022
    Date of Patent: February 6, 2024
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Luis Gabriel Gimenez-Lirola, Bailey Arruda
  • Patent number: 11878116
    Abstract: A tracheal sampling device is used to collect or acquire cells from an animal, such as at or near the tracheo-bronchial or larynx of an animal. The device includes a flexible and elongated shaft or stem, and a collection member at a distal end of the device. The collection member could be a swab or other member to best collect mucus. The device is used by inserting the collection end into an animal to position the collection member at or near the cell collection site, which may be in or around the larynx. The collection member is removed after collecting cells, which can be reviewed, tested, or otherwise managed to determine the presence of a disease or other bacteria. The length of the shaft or stem allows for optimal positioning of the swab in a variety of animal species and ages. The device can be disposed after each use.
    Type: Grant
    Filed: October 30, 2020
    Date of Patent: January 23, 2024
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Maria J. Clavijo, Kevin J. Brownfield, John K. Jackman, Bailey Arruda
  • Publication number: 20230302113
    Abstract: The present invention relates to the use of an immunogenic composition that comprises a porcine circovirus type 3 (PCV3) antigen for treatment of several clinical manifestations (diseases). Preferably, the clinical manifestations are associated with a PCV3 infection.
    Type: Application
    Filed: November 23, 2022
    Publication date: September 28, 2023
    Inventors: Arun IYER, Luis Alejandro Hernandez, Abby Patterson, Bailey Arruda, Luis Gabriel Gimenez-Lirola, Dave Michael Anstrom, Eric M. Vaughn, Pablo E Pineyro Pineiro, Troy James Kaiser, Joseph Ralph Hermann
  • Patent number: 11701419
    Abstract: The present invention relates to the use of an immunogenic composition that comprises a porcine circovirus type 3 (PCV3) antigen for treatment of several clinical manifestations (diseases). Preferably, the clinical manifestations are associated with a PCV3 infection.
    Type: Grant
    Filed: April 6, 2020
    Date of Patent: July 18, 2023
    Inventors: Arun Iyer, Luis Alejandro Hernandez, Abby Patterson, Bailey Arruda, Luis Gabriel Gimenez-Lirola, Dave Michael Anstrom, Eric M. Vaughn, Pablo E. Pineyro Pineiro, Troy James Kaiser, Joseph Ralph Hermann
  • Publication number: 20230174594
    Abstract: The present invention is directed to novel polynucleotides, polypeptides, and polyproteins of Mycoplasma surface proteins, all of which are useful in detecting infection and for the preparation of vaccines for treating and preventing diseases in swine and other animals. Vaccines provided according to the practice of the invention are effective against Mycoplasma infections. Detection and therapeutic polyclonal and monoclonal antibodies are also a feature of the present invention. Assays, kits, systems, and nanoparticle encapsulated compositions related to the polynucleotides, polypeptides, polyproteins, antibodies or fragments, derivatives, and variants thereof are also disclosed.
    Type: Application
    Filed: November 3, 2022
    Publication date: June 8, 2023
    Inventors: Luis Gabriel Gimenez-Lirola, Bailey Arruda
  • Patent number: 11524982
    Abstract: The present invention is directed to novel polynucleotides, polypeptides, and polyproteins of Mycoplasma surface proteins, all of which are useful in detecting infection and for the preparation of vaccines for treating and preventing diseases in swine and other animals. Vaccines provided according to the practice of the invention are effective against Mycoplasma infections. Detection and therapeutic polyclonal and monoclonal antibodies are also a feature of the present invention. Assays, kits, systems, and nanoparticle encapsulated compositions related to the polynucleotides, polypeptides, polyproteins, antibodies or fragments, derivatives, and variants thereof are also disclosed.
    Type: Grant
    Filed: January 28, 2020
    Date of Patent: December 13, 2022
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Luis Gabriel Gimenez-Lirola, Bailey Arruda
  • Patent number: 11124777
    Abstract: The present invention is directed to novel nucleotide and amino acid sequences of Porcine Sapelovirus (“PSV”), including novel genotypes thereof, all of which are useful in the preparation of vaccines for treating and preventing diseases in swine and other animals. Vaccines provided according to the practice of the invention are effective against multiple swine PSV genotypes and isolates. Diagnostic and therapeutic polyclonal and monoclonal antibodies are also a feature of the present invention, as are infectious clones useful in the propagation of the virus and in the preparation of vaccines. Particularly important aspects of the invention include polynucleotide constructs that replicate in tissue culture and in host swine. The invention also provides for novel full-length PSV genomes that can replicate efficiently in host animals and tissue culture.
    Type: Grant
    Filed: December 3, 2019
    Date of Patent: September 21, 2021
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Qi Chen, Bailey Arruda, Kent Schwartz, Phillip Gauger, Jianqiang Zhang
  • Publication number: 20210128712
    Abstract: The present invention relates to the use of an immunogenic composition that comprises a porcine circovirus type 3 (PCV3) antigen for treatment of several clinical manifestations (diseases). Preferably, the clinical manifestations are associated with a PCV3 infection.
    Type: Application
    Filed: April 6, 2020
    Publication date: May 6, 2021
    Inventors: Arun IYER, Luis Alejandro Hernandez, Abby Patterson, Bailey Arruda, Luis Gabriel Gimenez-Lirola, Dave Michael Anstrom, Eric M. Vaughn
  • Publication number: 20210128858
    Abstract: A tracheal sampling device is used to collect or acquire cells from an animal, such as at or near the tracheo-bronchial or larynx of an animal. The device includes a flexible and elongated shaft or stem, and a collection member at a distal end of the device. The collection member could be a swab or other member to best collect mucus. The device is used by inserting the collection end into an animal to position the collection member at or near the cell collection site, which may be in or around the larynx. The collection member is removed after collecting cells, which can be reviewed, tested, or otherwise managed to determine the presence of a disease or other bacteria. The length of the shaft or stem allows for optimal positioning of the swab in a variety of animal species and ages. The device can be disposed after each use.
    Type: Application
    Filed: October 30, 2020
    Publication date: May 6, 2021
    Inventors: Maria J. Clavijo, Kevin J. Brownfield, John K. Jackman, Bailey Arruda
  • Publication number: 20200239526
    Abstract: The present invention is directed to novel polynucleotides, polypeptides, and polyproteins of Mycoplasma surface proteins, all of which are useful in detecting infection and for the preparation of vaccines for treating and preventing diseases in swine and other animals. Vaccines provided according to the practice of the invention are effective against Mycoplasma infections. Detection and therapeutic polyclonal and monoclonal antibodies are also a feature of the present invention. Assays, kits, systems, and nanoparticle encapsulated compositions related to the polynucleotides, polypeptides, polyproteins, antibodies or fragments, derivatives, and variants thereof are also disclosed.
    Type: Application
    Filed: January 28, 2020
    Publication date: July 30, 2020
    Inventors: Luis Gabriel Gimenez-Lirola, Bailey Arruda
  • Publication number: 20200172878
    Abstract: The present invention is directed to novel nucleotide and amino acid sequences of Porcine Sapelovirus (“PSV”), including novel genotypes thereof, all of which are useful in the preparation of vaccines for treating and preventing diseases in swine and other animals. Vaccines provided according to the practice of the invention are effective against multiple swine PSV genotypes and isolates. Diagnostic and therapeutic polyclonal and monoclonal antibodies are also a feature of the present invention, as are infectious clones useful in the propagation of the virus and in the preparation of vaccines. Particularly important aspects of the invention include polynucleotide constructs that replicate in tissue culture and in host swine. The invention also provides for novel full-length PSV genomes that can replicate efficiently in host animals and tissue culture.
    Type: Application
    Filed: December 3, 2019
    Publication date: June 4, 2020
    Inventors: Qi Chen, Bailey Arruda, Kent Schwartz, Phillip Gauger, Jianqiang Zhang