Patents by Inventor Bailin Liang

Bailin Liang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating conditions using anti-IL-6 antibodies
    Patent number: 8067003
    Abstract: Anti-IL-6 antibodies are used to treat IL-6 related conditions, such as rheumatoid arthritis, osteoarthritis, osteolysis, aseptic loosening of orthopedic implants, systemic lupus erythematosus, cutaneous lupus erythematosus, lupus nephritis, type 2 diabetes mellitus, chronic obstructive pulmonary disease, and renal cell carcinoma.
    Type: Grant
    Filed: October 8, 2010
    Date of Patent: November 29, 2011
    Assignees: Centocor, Inc., Applied Molecular Evolution, Inc.
    Inventors: Yan Chen, Debra Gardner, David M. Knight, Michael W. Lark, Bailin Liang, David J. Shealy, Xiao-Yu R. Song, Vedrana Stojanovic-Susulic, Raymond W. Sweet, Susan H. Tam, Sheng-Jiun Wu, Jing Yang, David Matthew Marquis, Eric Michael Smith, Alain Philippe Vasserot
  • Methods of Diagnosing and Treating Conditions Using Anti-IL-6 Antibodies
    Publication number: 20110081355
    Abstract: Anti-IL-6 antibodies are used to treat IL-6 related conditions, such as rheumatoid arthritis, osteoarthritis, osteolysis, aseptic loosening of orthopedic implants, systemic lupus erythematosus, cutaneous lupus erythematosus, lupus nephritis, type 2 diabetes mellitus, chronic obstructive pulmonary disease, and renal cell carcinoma.
    Type: Application
    Filed: October 8, 2010
    Publication date: April 7, 2011
    Inventors: YAN CHEN, DEBRA GARDNER, DAVID M. KNIGHT, MICHAEL W. LARK, BAILIN LIANG, DAVID J. SHEALY, XIAO-YU R. SONG, VEDRANA STOJANOVIC-SUSULIC, RAYMOND W. SWEET, SUSAN H. TAM, SHENG-JIUN WU, JING YANG, DAVID MATTHEW MARQUIS, ERIC MICHAEL SMITH, ALAIN PHILIPPE VASSEROT
  • Anti-IL-6 antibody nucleic acid molecules and methods
    Patent number: 7833755
    Abstract: Anti-IL-6 antibody nucleic acids, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
    Type: Grant
    Filed: May 22, 2009
    Date of Patent: November 16, 2010
    Inventors: Yan Chen, Debra Gardner, David M. Knight, Michael W. Lark, Bailin Liang, David J. Shealy, Xiao-Yu R. Song, Vedrana Stojanovic-Susulic, Raymond W. Sweet, Susan H. Tam, Sheng-Jiun Wu, Jing Yang, David Matthew Marquis, Eric Michael Smith, Alain Philippe Vasserot
  • Anti-IL-6 Antibody Nucleic Acid Molecules and Methods
    Publication number: 20090239258
    Abstract: Anti-IL-6 antibody nucleic acids, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
    Type: Application
    Filed: May 22, 2009
    Publication date: September 24, 2009
    Inventors: Yan Chen, Debra Gardner, David M. Knight, Michael W. Lark, Bailin Liang, David J. Shealy, Xiao-Yu R. Song, Vedrana Stojanovic-Susulic, Raymond W. Sweet, Susan H. Tam, Sheng-Jiun Wu, Jing Yang, David Matthew Marquis, Eric Michael Smith, Alain Philippe Vasserot
  • Anti-il-6 antibodies, compositions, methods and uses
    Patent number: 7560112
    Abstract: An anti-IL-6 antibody, including isolated nucleic acids that encode at least one anti-IL-6 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
    Type: Grant
    Filed: April 28, 2006
    Date of Patent: July 14, 2009
    Assignees: Applied Molecular Evolution, Inc., Centocor Ortho Biotech Inc.
    Inventors: Yan Chen, Debra Gardner, David M. Knight, Michael W. Lark, Bailin Liang, David J. Shealy, Xiao-Yu R. Song, Vedrana Stojanovic-Susulic, Raymond W. Sweet, Susan H. Tam, Sheng-Jiun Wu, Jing Yang, David Matthew Marquis, Eric Michael Smith, Alain Philippe Vasserot
  • CNGH0010 Specific Polynucleotides, Polypeptides, Antibodies, Compositions, Methods and Uses
    Publication number: 20090137783
    Abstract: Novel polypeptides (CNGH0010) and antibodies, including specified portions or variants, specific for at least one such CNGH0010 polypeptide, variant, or fragment thereof, as well as nucleic acids encoding such CNGH0010 polypeptides and antibodies, complementary nucleic acids, vectors, host cells, and methods of making and using thereof, are useful for therapeutic and diagnostic formulations, administration and devices. The aforesaid polypeptides can be used to generate human, primate, rodent, mammalian, chimeric, humanized and/or CDR-grafted anti-CNGH0010 antibodies. The CNGH0010 polypeptides and antibodies are used in modulating or treating at least one CNGH0010-related disease in a cell, tissue, organ, animal, or patient.
    Type: Application
    Filed: January 13, 2009
    Publication date: May 28, 2009
    Inventors: Xiao-yu R. Song, Chong Huang, Keying Ma, Bailin Liang, Michael Naso
  • CXCL13 Antagonists and Their Use for the Treatment of Inflammatory Diseases
    Publication number: 20090136512
    Abstract: Methods of treating disorders related to CXCL13 activity utilize CXCL13 antagonists and, optionally, TNF? antagonists, such as antibodies, including specified portions or variants, polypeptides, polynucleotides, siRNA, shRNA, ribozymes, and DNAzymes. Disorders related to CXCL13 activity include inflammatory disorders, such as pulmonary disorders, for example, asthma, emphysema, and COPD, and systemic lupus erythematosus.
    Type: Application
    Filed: March 31, 2008
    Publication date: May 28, 2009
    Inventors: Peter Bugelski, Deg Griswold, Bailin Liang, Robert T. Sarisky
  • CNGH0010 specific polynucleotides, polypeptides, antibodies, compositions, methods and uses
    Patent number: 7479479
    Abstract: Novel polypeptides (CNGH0010) and antibodies, including specified portions or variants, specific for at least one such CNGH0010 polypeptide, variant, or fragment thereof, as well as nucleic acids encoding such CNGH0010 polypeptides and antibodies, complementary nucleic acids, vectors, host cells, and methods of making and using thereof, are useful for therapeutic and diagnostic formulations, administration and devices. The aforesaid polypeptides can be used to generate human, primate, rodent, mammalian, chimeric, humanized and/or CDR-grafted anti-CNGH0010 antibodies. The CNGH0010 polypeptides and antibodies are used in modulating or treating at least one CNGH0010-related disease in a cell, tissue, organ, animal, or patient.
    Type: Grant
    Filed: February 28, 2007
    Date of Patent: January 20, 2009
    Assignee: Centocor, Inc.
    Inventors: Xiao-yu R. Song, Chong Huang, Keying Ma, Bailin Liang, Michael Naso
  • CNGH0010 Specific Polynucleotides, Polypeptides, Antibodies, Compositions, Methods and Uses
    Publication number: 20080044422
    Abstract: Novel polypeptides (CNGH0010) and antibodies, including specified portions or variants, specific for at least one such CNGH0010 polypeptide, variant, or fragment thereof, as well as nucleic acids encoding such CNGH0010 polypeptides and antibodies, complementary nucleic acids, vectors, host cells, and methods of making and using thereof, are useful for therapeutic and diagnostic formulations, administration and devices. The aforesaid polypeptides can be used to generate human, primate, rodent, mammalian, chimeric, humanized and/or CDR-grafted anti-CNGH0010 antibodies. The CNGH0010 polypeptides and antibodies are used in modulating or treating at least one CNGH0010-related disease in a cell, tissue, organ, animal, or patient.
    Type: Application
    Filed: February 28, 2007
    Publication date: February 21, 2008
    Inventors: Xiao-yu Song, Chong Huang, Keying Ma, Bailin Liang, Michael Naso
  • CNGH0010 specific polynucleotides, polypeptides, antibodies, compositions, methods and uses
    Patent number: 7326687
    Abstract: Novel polypeptides (CNGH0010) and antibodies, including specified portions or variants, specific for at least one such CNGH0010 polypeptide, variant, or fragment thereof, as well as nucleic acids encoding such CNGH0010 polypeptides and antibodies, complementary nucleic acids, vectors, host cells, and methods of making and using thereof, are useful for therapeutic and diagnostic formulations, administration and devices. The aforesaid polypeptides can be used to generate human, primate, rodent, mammalian, chimeric, humanized and/or CDR-grafted anti-CNGH0010 antibodies. The CNGH0010 polypeptides and antibodies are used in modulating or treating at least one CNGH0010-related disease in a cell, tissue, organ, animal, or patient.
    Type: Grant
    Filed: April 30, 2004
    Date of Patent: February 5, 2008
    Assignee: Centocor, Inc.
    Inventors: Xiao-Yu Song, Chris Huang, Keying Ma, Bailin Liang, Michael Naso
  • CXCL13 Antagonists and Their Use for the Treatment of Inflammatory Diseases
    Publication number: 20080014201
    Abstract: Methods of treating disorders related to CXCL13 activity utilize CXCL13 antagonists and, optionally, TNF? antagonists, such as antibodies, including specified portions or variants, polypeptides, polynucleotides, siRNA, shRNA, ribozymes, and DNAzymes. Disorders related to CXCL13 activity include inflammatory disorders, such as pulmonary disorders, for example, asthma, emphysema, and COPD, and systemic lupus erythematosus.
    Type: Application
    Filed: April 20, 2007
    Publication date: January 17, 2008
    Inventors: Peter Bugelski, Anuk Das, Donald Griswold, Bailin Liang, Li Li, Robert Sarisky, Xiaozhou Shang
  • Anti-IL-6 antibodies, compositions, methods and uses
    Publication number: 20060257407
    Abstract: An anti-IL-6 antibody, including isolated nucleic acids that encode at least one anti-IL-6 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
    Type: Application
    Filed: April 28, 2006
    Publication date: November 16, 2006
    Inventors: Yan Chen, Debra Gardner, David Knight, Michael Lark, Bailin Liang, David Shealy, Xiao-Yu Song, Vedrana Stojanovic-Susulic, Raymond Sweet, Susan Tam, Sheng-Jiun Wu, Jing Yang, David Marquis, Eric Smith, Alain Vasserot
  • CNGH0010 specific polynucleotides, polypeptides, antibodies, compositions, methods and uses
    Publication number: 20060141479
    Abstract: Novel polypeptides (CNGH0010) and antibodies, including specified portions or variants, specific for at least one such CNGH0010 polypeptide, variant, or fragment thereof, as well as nucleic acids encoding such CNGH0010 polypeptides and antibodies, complementary nucleic acids, vectors, host cells, and methods of making and using thereof, are useful for therapeutic and diagnostic formulations, administration and devices. The aforesaid polypeptides can be used to generate human, primate, rodent, mammalian, chimeric, humanized and/or CDR-grafted anti-CNGH0010 antibodies. The CNGH0010 polypeptides and antibodies are used in modulating or treating at least one CNGH0010-related disease in a cell, tissue, organ, animal, or patient.
    Type: Application
    Filed: April 30, 2004
    Publication date: June 29, 2006
    Inventors: Xiao-Yu Song, Chris Huang, Keying Ma, Bailin Liang, Michael Naso