Patents by Inventor Bailin Tu

Bailin Tu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TRUNCATED HUMAN VITAMIN D BINDING PROTEIN AND MUTATION AND FUSION THEREOF AND RELATED MATERIALS AND METHODS OF USE
    Publication number: 20130295593
    Abstract: Vitamin D binding proteins (DBP), in particular truncated DBP and mutated, truncated DBP, as well as fusion proteins thereof, nucleic acid molecules encoding same, vectors, host cells, and methods, kits and solid supports for determining the total amount of 25-hydroxy vitamin D2 and 25-hydroxy vitamin D3 in a test sample.
    Type: Application
    Filed: December 23, 2012
    Publication date: November 7, 2013
    Inventors: Christian Beckert, Susan E. Brophy, Jonathan Grote, Dagang Huang, Jan Schultess, Bailin Tu
  • ANTIBODIES WHICH DETECT PIVKAII AND METHODS OF USE THEREOF
    Publication number: 20130217145
    Abstract: The present invention relates to antibodies or binding proteins which bind to PIVKA II and may be used, for example, in the diagnosis, treatment and prevention of hepatocellular carcinoma (HCC), liver cancer and related conditions.
    Type: Application
    Filed: September 6, 2012
    Publication date: August 22, 2013
    Applicant: ABBOTT LABORATORIES
    Inventors: Toru Yoshimura, Sharmila Manoj, Bailin Tu, Barry L. Dowell, Gangamani Beligere, Qiaoqiao Ruan, Anthony S. Muehoff
  • Neutrophil gelatinase-associated lipocalin (NGAL) protein isoforms enriched from urine and recombinant chinese hamster ovary (CHO) cells and related compositions, antibodies, and methods of enrichment, analysis and use
    Patent number: 8394606
    Abstract: A composition comprising neutrophil gelatinase-associated lipocalin (NGAL), which has been enriched from urine, has a molecular weight of about 24.9 kDa to about 25.9 kDa, and comprises a plurality of isoforms having isoelectric points (pIs) ranging from about 5.9 to about 9.1; a composition comprising NGAL, which has been enriched from recombinant Chinese hamster ovary (CHO) cells, has a molecular weight of about 25.9 kDa to about 27.9 kDa, and comprises a plurality of isoforms having pIs ranging from about 5.6 to about 9.
    Type: Grant
    Filed: November 4, 2009
    Date of Patent: March 12, 2013
    Assignee: Abbott Laboratories
    Inventors: Salman Ali, Ryan M. Bonn, Frank C. Grenier, Tracey D. Rae, Kevin R. Rupprecht, Hina N. Syed, Bailin Tu, Joan D. Tyner, Ryan F. Workman
  • GLYCOSYLATED MAMMALIAN NGAL AND USE THEREOF
    Publication number: 20120142022
    Abstract: The present invention relates to glycosylated mammalian NGAL, and methods of using said glycosylated mammalian NGAL.
    Type: Application
    Filed: January 19, 2012
    Publication date: June 7, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Bailin Tu, Joan D. Tyner, Lowell J. Tyner
  • ANTI-T. CRUZI ANTIBODIES AND METHODS OF USE
    Publication number: 20120122125
    Abstract: The present disclosure is directed to reagents and methods of using the reagents to detect epitopes of Trypanosoma cruzi.
    Type: Application
    Filed: January 19, 2012
    Publication date: May 17, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Susan E. Brophy, David J. Hawksworth, Dinesh O. Shah, Robert W. Siegel, Bryan C. Tieman, Bailin Tu, Joan D. Tyner, Robert N. Ziemann
  • ANTIBODIES TO TROPONIN I AND METHODS OF USE THEREOF
    Publication number: 20120076803
    Abstract: The subject invention relates to antibodies to troponin I as well as methods of use thereof. In particular, such antibodies may be used to detect Troponin I in a patient and may also be used in the diagnosis of, for example, a myocardial infarction or acute coronary syndrome.
    Type: Application
    Filed: February 23, 2010
    Publication date: March 29, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Susan E. Brophy, Bailin Tu, Joan D. Tyner, Lowell J. Tyner, Dagang Huang, Robert N. Ziemann
  • RECOMBINANT ANTIBODIES AGAINST HEPATITIS C VIRUS AND METHODS OF OBTAINING AND USING SAME
    Publication number: 20110263436
    Abstract: Recombinant antibodies, including chimeric antibodies, specific for hepatitis C (HCV) antigenic proteins are provided. The recombinant antibodies specifically bind to diagnostically relevant regions of HCV proteins and are thus suitable for use, for example, as diagnostic reagents for the detection of HCV, and/or as standardization reagents or positive control reagents in assays for the detection of HCV. The recombinant antibodies can also be used in the treatment or prevention of a HCV infection.
    Type: Application
    Filed: November 22, 2010
    Publication date: October 27, 2011
    Applicant: ABBOTT LABORATORIES
    Inventors: Bailin Tu, Joan D. Tyner, James W. Scheffel, Michael K. White, Jeffrey M. Werneke, Robert N. Ziemann, David J. Hawksworth, Mary S. Pinkus, Robin A. Gutierrez
  • Antibodies to troponin I and methods of use thereof
    Patent number: 8030026
    Abstract: The subject invention relates to antibodies to troponin I as well as methods of use thereof. In particular, such antibodies may be used to detect Troponin I in a patient and may also be used in the diagnosis of, for example, a myocardial infarction or acute coronary syndrome.
    Type: Grant
    Filed: February 24, 2009
    Date of Patent: October 4, 2011
    Assignee: Abbott Laboratories
    Inventors: Susan E. Brophy, Bailin Tu, Joan D. Tyner, Lowell J. Tyner, legal representative, Dagang Huang, Robert N. Ziemann
  • Recombinant antibodies against hepatitis C virus and methods of obtaining and using same
    Patent number: 7858752
    Abstract: Recombinant antibodies, including chimeric antibodies, specific for hepatitis C (HCV) antigenic proteins are provided. The recombinant antibodies specifically bind to diagnostically relevant regions of HCV proteins and are thus suitable for use, for example, as diagnostic reagents for the detection of HCV, and/or as standardization reagents or positive control reagents in assays for the detection of HCV. The recombinant antibodies can also be used in the treatment or prevention of a HCV infection.
    Type: Grant
    Filed: December 5, 2006
    Date of Patent: December 28, 2010
    Assignee: Abbott Laboratories
    Inventors: Bailin Tu, Joan D. Tyner, James W. Scheffel, Michael K. White, Jeffrey M. Werneke, Robert N. Ziemann, David J. Hawksworth, Mary S. Pinkus, Robin A. Gutierrez
  • IMMUNOASSAYS AND KITS FOR THE DETECTION OF NGAL
    Publication number: 20100227775
    Abstract: The present invention relates to NGAL immunoassays and kits, and to methods of using glycosylated mammalian NGAL and antibodies that bind to mammalian NGAL in immunoassays and kits. Among other things, the methods and kits can be employed to determine the amount of human NGAL monomer in a test sample, as well as to determine the proportion of human NGAL monomer to human NGAL dimer contained in a test sample.
    Type: Application
    Filed: May 21, 2010
    Publication date: September 9, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Larry G. Birkenmeyer, Suresh M. Desai, Frank C. Grenier, David J. Hawksworth, Edward T. Olejniczak, Qiaoqiao Ruan, Robert W. Siegel, Sergey Y. Tetin, Bryan C. Tieman, Bailin Tu, Joan D. Tyner, Ryan F. Workman, Robert N. Ziemann
  • ANTIBODIES TO TROPONIN I AND METHODS OF USE THEREOF
    Publication number: 20100216720
    Abstract: The subject invention relates to antibodies to troponin I as well as methods of use thereof. In particular, such antibodies may be used to detect Troponin I in a patient and may also be used in the diagnosis of, for example, a myocardial infarction or acute coronary syndrome.
    Type: Application
    Filed: February 24, 2009
    Publication date: August 26, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Susan E. Brophy, Bailin Tu, Joan D. Tyner, Dagang Huang, Robert N. Ziemann, Lowell J. Tyner
  • NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN (NGAL) PROTEIN ISOFORMS ENRICHED FROM URINE AND RECOMBINANT CHINESE HAMSTER OVARY (CHO) CELLS AND RELATED COMPOSITIONS, ANTIBODIES, AND METHODS OF ENRICHMENT, ANALYSIS AND USE
    Publication number: 20100116662
    Abstract: A composition comprising neutrophil gelatinase-associated lipocalin (NGAL), which has been enriched from urine, has a molecular weight of about 24.9 kDa to about 25.9 kDa, and comprises a plurality of isoforms having isoelectric points (pIs) ranging from about 5.9 to about 9.1; a composition comprising NGAL, which has been enriched from recombinant Chinese hamster ovary (CHO) cells, has a molecular weight of about 25.9 kDa to about 27.9 kDa, and comprises a plurality of isoforms having pIs ranging from about 5.6 to about 9.
    Type: Application
    Filed: November 4, 2009
    Publication date: May 13, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Salman Ali, Ryan M. Bonn, Frank C. Grenier, Tracey D. Rae, Kevin R. Rupprecht, Hina N. Syed, Bailin Tu, Joan D. Tyner, Ryan F. Workman
  • PIGF-1 ASSAY AND KITS AND COMPONENTS THEREOF
    Publication number: 20100015637
    Abstract: The present disclosure relates to glycosylated and deglycosylated human PlGF-1, methods of using the glycosylated and deglycosylated human PlGF-1, antibodies that bind to human PlGF-1, methods of using the antibodies and human PlGF-1 immunoassays and kits.
    Type: Application
    Filed: June 16, 2009
    Publication date: January 21, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Susan E. Brophy, Lianli Chi, Saul A. Datwyler, David J. Hawksworth, Don M. Laird, Sharmila Manoj, Mary S. Pinkus, Dominick L. Pucci, Carol S. Ramsay, David C. Sogin, Bailin Tu, Joan D. Tyner, Lowell J Tyner, Zhiguang Yu, Robert N. Ziemann
  • IMMUNOASSAYS AND KITS FOR THE DETECTION OF NGAL
    Publication number: 20090269777
    Abstract: The present invention relates to NGAL immunoassays and kits, and to methods of using glycosylated mammalian NGAL and antibodies that bind to mammalian NGAL in immunoassays and kits. Among other things, the methods and kits can be employed to determine the amount of human NGAL monomer in a test sample, as well as to determine the proportion of human NGAL monomer to human NGAL dimer contained in a test sample.
    Type: Application
    Filed: April 16, 2008
    Publication date: October 29, 2009
    Applicant: Abbott Laboratories
    Inventors: Larry G. Birkenmeyer, Suresh M. Desai, Frank C. Grenier, David J. Hawksworth, Edward T. Olejniczak, Qiaoqiao Ruan, Robert W. Siegel, Sergey Y. Tetin, Bryan C. Tieman, Bailin Tu, Joan D. Tyner, Lowell J. Tyner, Ryan F. Workman, Robert N. Ziemann
  • ANTIBODIES THAT BIND TO MAMMALIAN NGAL AND USES THEREOF
    Publication number: 20090263894
    Abstract: The present invention relates to antibodies specific for glycosylated mammalian NGAL, and to methods of making and using such antibodies.
    Type: Application
    Filed: December 5, 2008
    Publication date: October 22, 2009
    Applicant: ABBOTT LABORATORIES
    Inventors: Larry G. Birkenmeyer, Suresh M. Desai, David J. Hawksworth, Edward T. Olejniczak, Qiaoqiao Ruan, Robert W. Siegel, Sergey Y. Tetin, Bryan C. Tieman, Bailin Tu, Joan D. Tyner, Robert N. Ziemann
  • Anti-T. Cruzi Antibodies and Methods of Use
    Publication number: 20090203037
    Abstract: The present disclosure is directed to reagents and methods of using the reagents to detect epitopes of Trypanosoma cruzi.
    Type: Application
    Filed: December 23, 2008
    Publication date: August 13, 2009
    Applicant: Abbott Laboratories
    Inventors: Susan E. Brophy, David J. Hawksworth, Dinesh O. Shah, Robert W. Siegel, Bryan C. Tieman, Bailin Tu, Joan D. Tyner, Lowell J. Tyner, Robert N. Ziemann
  • GLYCOSYLATED MAMMALIAN NGAL AND USE THEREOF
    Publication number: 20090176274
    Abstract: The present invention relates to glycosylated mammalian NGAL, and methods of using said glycosylated mammalian NGAL.
    Type: Application
    Filed: December 8, 2008
    Publication date: July 9, 2009
    Applicant: ABBOTT LABORATORIES
    Inventors: Bailin Tu, Joan D. Tyner
  • IMMUNOASSAYS AND KITS FOR THE DETECTION OF NGAL
    Publication number: 20090123946
    Abstract: The present invention relates to NGAL immunoassays and kits, and to methods of using glycosylated mammalian NGAL and antibodies that bind to mammalian NGAL in immunoassays and kits. Among other things, the methods and kits can be employed to determine the amount of human NGAL monomer in a test sample, as well as to determine the proportion of human NGAL monomer to human NGAL dimer contained in a test sample.
    Type: Application
    Filed: December 5, 2008
    Publication date: May 14, 2009
    Applicant: ABBOTT LABORATORIES
    Inventors: Larry G. Birkenmeyer, Suresh M. Desai, Frank C. Grenier, David J. Hawksworth, Edward T. Olejniczak, Qiaoqiao Ruan, Robert W. Siegel, Sergey Y. Tetin, Bryan C. Tieman, Bailin Tu, Joan D. Tyner, Ryan F. Workman, Robert N. Ziemann, Lowell J. Tyner
  • ANTIBODIES THAT BIND TO MAMMALIAN NGAL AND USES THEREOF
    Publication number: 20090124022
    Abstract: The present invention relates to antibodies specific for glycosylated mammalian NGAL, and to methods of making and using such antibodies.
    Type: Application
    Filed: April 16, 2008
    Publication date: May 14, 2009
    Applicant: Abbott Laboratories
    Inventors: Larry G. Birkenmeyer, Suresh M. Desai, David J. Hawksworth, Edward T. Olejniczak, Qiaoqiao Ruan, Robert W. Siegel, Sergey Y. Tetin, Bryan C. Tieman, Bailin Tu, Joan D. Tyner, Robert N. Ziemann, Lowell J. Tyner
  • GLYCOSYLATED MAMMALIAN NGAL AND USE THEREOF
    Publication number: 20090123970
    Abstract: The present invention relates to glycosylated mammalian NGAL, and methods of using said glycosylated mammalian NGAL.
    Type: Application
    Filed: December 5, 2008
    Publication date: May 14, 2009
    Applicant: ABBOTT LABORATORIES
    Inventors: Bailin Tu, Joan D. Tyner