Patents by Inventor Bainian Feng

Bainian Feng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions utilizing quinazolinones
    Patent number: 7230000
    Abstract: Quinazolinones of formulae 1a, 1b, 1c and 1d are disclosed.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: June 12, 2007
    Assignee: Cytokinetics, Incorporated
    Inventors: Jeffrey T. Finer, Gustave Bergnes, Whitney W. Smith, John C. Chabala, Bainian Feng
  • Compounds, compositions, and methods
    Patent number: 7214800
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
    Type: Grant
    Filed: May 8, 2003
    Date of Patent: May 8, 2007
    Assignees: Cytokinetics, Inc., Smithkline Beecham Corporation
    Inventors: Bainian Feng, Gustave Bergnes, David J. Morgans, Jr., Dashyant Dhanak, Steven David Knight, Michael Gerard Darcy
  • Compositions and methods for treating heart failure
    Publication number: 20060173024
    Abstract: Certain substituted benzamide derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
    Type: Application
    Filed: February 14, 2006
    Publication date: August 3, 2006
    Applicant: Cytokinetics, Inc.
    Inventors: Fady Malik, Adam Tomasi, Bainian Feng, Erica Kraynack, Kathleen Elias, Pu-Ping Lu, Whitney Smith, Xiangping Qian, David Morgans
  • Compositions and methods for treating heart failure
    Patent number: 7053094
    Abstract: Certain substituted benzamide derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
    Type: Grant
    Filed: January 20, 2005
    Date of Patent: May 30, 2006
    Assignee: Cytokinetics, Inc.
    Inventors: Fady Malik, Adam Lewis Tomasi, Bainian Feng, Erica Anne Kraynack, Kathleen A. Elias, Pu-Ping Lu, Whitney Walter Smith, Xiangping Qian, David J. Morgans, Jr.
  • Compounds, compositions, and methods
    Publication number: 20060094735
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
    Type: Application
    Filed: October 27, 2005
    Publication date: May 4, 2006
    Inventors: Bainian Feng, Gustave Bergnes, David Morgans, Dashyant Dhanak, Steven Knight, Michael Darcy
  • Compounds, compositions and methods
    Publication number: 20060020008
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
    Type: Application
    Filed: June 15, 2005
    Publication date: January 26, 2006
    Inventors: Andrew McDonald, Gustave Bergnes, Bainian Feng, David Morgans, Steven Knight, Kenneth Newlander, Dashyant Dhanak, Christopher Brook
  • Inhibitors of IAP
    Publication number: 20060014700
    Abstract: The invention provides novel inhibitors of IAP that are useful as therapeutic agents for treating malignancies where the compounds have the general formula I: wherein X, Y, A, R1, R2, R3, R4, R4?, R5, R5?, R6 and R6? are as described herein.
    Type: Application
    Filed: July 5, 2005
    Publication date: January 19, 2006
    Applicant: Genentech, Inc.
    Inventors: Frederick Cohen, Kurt Deshayes, Wayne Fairbrother, Bainian Feng, John Flygare, Lewis Gazzard, Vickie Tsui
  • Heterocyclic self-immolative linkers and conjugates
    Publication number: 20050256030
    Abstract: The present invention provides heterocyclic linker compounds useful for linking drug moieties to ligands. The compounds also include drug-ligand conjugates comprising a ligand capable of targeting a selected cell population, and a drug connected to the ligand by a heterocyclic linker moiety. The linker moiety comprises a peptide sequence that is a substrate for an intracellular enzyme, for example a cathepsin, that cleaves the peptide at an amide bond. The peptide further contains a self-immolating moiety which connects the drug and the protein peptide sequence. Upon cleavage of the peptide sequence by an intracellular enzyme the self-immolating moiety cleaves itself from the drug moiety such that the drug moiety is in an underivatized and active form.
    Type: Application
    Filed: February 22, 2005
    Publication date: November 17, 2005
    Inventor: Bainian Feng
  • Methods and compositions utilizing quinazolinones
    Publication number: 20050187232
    Abstract: Quinazolinones of formulae 1a, 1b, 1c and 1d are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity.
    Type: Application
    Filed: March 21, 2005
    Publication date: August 25, 2005
    Inventors: Jeffrey Finer, Gustave Bergnes, Whitney Smith, John Chabala, Bainian Feng
  • Compounds, compositions and methods
    Patent number: 6924376
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
    Type: Grant
    Filed: April 11, 2003
    Date of Patent: August 2, 2005
    Assignees: Cytokinetics, Inc., Smithkline Beecham Corporation
    Inventors: Andrew McDonald, Gustave Bergnes, Bainian Feng, David J. Morgans, Jr., Steven David Knight, Kenneth A. Newlander, Dashyant Dhanak, Christopher A. Brook
  • Compositions and methods for treating heart failure
    Publication number: 20050148638
    Abstract: Certain substituted benzamide derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
    Type: Application
    Filed: January 20, 2005
    Publication date: July 7, 2005
    Applicant: Cytokinetics, Inc.
    Inventors: Fady Malik, Adam Tomasi, Bainian Feng, Erica Kraynack, Kathleen Elias, Pu-Ping Lu, Whitney Smith, Xiangping Qian, David Morgans
  • Compositions and methods for treating heart failure
    Patent number: 6908923
    Abstract: Certain substituted benzamide derivatives of Formula I: selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
    Type: Grant
    Filed: December 20, 2002
    Date of Patent: June 21, 2005
    Assignee: Cytokinetics, Inc.
    Inventors: Fady Malik, Adam Lewis Tomasi, Bainian Feng, Erica Anne Kraynack, Kathleen A. Elias, Pu-Ping Lu, Whitney Walter Smith, Xiangping Qian, David J. Morgans, Jr.
  • Methods and compositions utilizing quinazolinones
    Publication number: 20040254203
    Abstract: Quinazolinones of formulae 1a, 1b, 1c and 1d are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity.
    Type: Application
    Filed: July 20, 2004
    Publication date: December 16, 2004
    Applicant: Cytokinetics, Inc.
    Inventors: Jeffrey T. Finer, Gustave Bergnes, Whitney W. Smith, John C. Chabala, Bainian Feng
  • Compounds, compositions and methods
    Publication number: 20040082638
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
    Type: Application
    Filed: April 11, 2003
    Publication date: April 29, 2004
    Applicant: Cytokinetics, Inc.
    Inventors: Andrew McDonald, Gustave Bergnes, Bainian Feng, David J. Morgans, Steven David Knight, Kenneth A. Newlander, Dashyant Dhanak, Christopher A. Brook
  • Compounds, compositins, and methods
    Publication number: 20040077668
    Abstract: Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of KSP are disclosed.
    Type: Application
    Filed: May 8, 2003
    Publication date: April 22, 2004
    Applicants: Cytokinetics, Inc., SmithKline Beecham
    Inventors: Bainian Feng, Gustave Bergnes, David J. Morgans, Dashyant Dhanak, Steven David Knight, Michael Gerard Darcy
  • Methods and compositions utilizing quinazolinones
    Publication number: 20040023996
    Abstract: Quinazolinones of formulae (a, b, c and d) are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity.
    Type: Application
    Filed: August 15, 2003
    Publication date: February 5, 2004
    Inventors: Jeffrey T. Finer, Gustave Bergnes, Bainian Feng, Whitney W. Smith, John C. Chabala, David J. Morgans Jr
  • Methods and compositions utilizing quinazolinones
    Patent number: 6630479
    Abstract: Quinazolinones of formulae 1a, 1b, 1c and 1d are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: October 7, 2003
    Assignee: Cytokinetics, Inc.
    Inventors: Jeffrey T. Finer, Gustave Bergnes, Whitney W. Smith, John C. Chabala, Bainian Feng
  • Compositions and methods for treating heart failure
    Publication number: 20030158233
    Abstract: Certain substituted benzamide derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
    Type: Application
    Filed: December 20, 2002
    Publication date: August 21, 2003
    Inventors: Fady Malik, Adam Lewis Tomasi, Bainian Feng, Erica Anne Kraynack, Kathleen A. Elias, Pu-Ping Lu, Whitney Walter Smith, Xiangping Qian, David J. Morgans,
  • Compositions and methods for treating heart failure
    Publication number: 20030158186
    Abstract: Certain substituted benzamide derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
    Type: Application
    Filed: December 20, 2002
    Publication date: August 21, 2003
    Inventors: Fady Malik, Adam Lewis Tomasi, Bainian Feng, Bradley Paul Morgan, Han-Jie Zhou, Kathleen A. Elias, Pu-Ping Lu, Whitney Walter Smith, Xiangping Qian, David J. Morgans,
  • Methods and compositions utilizing quinazolinones
    Patent number: 6562831
    Abstract: Quinazolinones of formulae 1a, 1b, 1c and 1d are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: May 13, 2003
    Assignee: Cytokinetics, Inc.
    Inventors: Jeffrey T. Finer, Gustave Bergnes, Whitney W. Smith, John C. Chabala, Bainian Feng